The electrocardiograms of 60 children with severe chronic anemia of vari ous etiologies are reviewed. Twenty-five had repeated electrocardiograms during or after treatment. Abnormal electrocardiograms consistent with mild ischemia secondary to impaired oxygen delivery were found in 11 patients, ten of whom belonged to a low socioeconomic group. The elec trocardiographic changes were variable, relatively infrequent, and mild. They improved or disappeared in eight of the 11 patients, after treatment.
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