Chronic Hypervitaminosis A with Intracranial Hypertension and Low Cerebrospinal Fluid Concentration of Protein

Abstract

An unusually high dietary intake can lead to vitamin A intoxication. These two children had clinical and radiologic evidences of increased intracranial pressure and low cerebrospinal fluid protein concentrations.

Get full access to this article

View all access options for this article.

References

Quoted by Bloch, H.S. : Chronic Hypervitaminosis A. Minn. Med. 38: 627, 1955.

Rodahl, K. : Toxicity of Polar Bear Liver. Nature (London) 164, 530. 1949.

Josephs, H.W. : Hypervitaminosis A and Carotenemia. Am. J. Dis. Child. 67: 33, 1944.

Caffey, J. Chronic Poisoning Due to Excess of Vitamin A—Description of the Clinical and Roentgen Manifestations in Infants and Young Children. Pediatrics 5: 672, 1950.

Oliver, T.K. , Jr.: Chronic Vitamin A Intoxication: Report of a Case in an Older Child and Review of the Literature. Am. J. Dis. Child. 95: 57, 1958.

Stimson, W.H. : Vitamin A Intoxication in Adults —Report of a Case with Review of the Literature. N. Engl. J. Med. 265: 369, 1961.

Feldman, M.H. and Schlezinger, N.S. : Benign Intracranial Hypertension Associated with Hypervitaminosis A. Arch. Neurol. ( Chicago) 22: 1, (Jan.) 1970.

Rotnam, P.E. and Knudson, A.G. : Hypervitaminosis A: A Review with a Discussion of Vitamin A. Am. J. Dis. Child. 85: 316, 1953.

Bass, M.D. : The Relation of Vitamin A to Cerebrospinal Fluid Pressure—A Review. J. Mount Sinai Hospital N. Y. 24: 713, 1957 .

10.

Widell, S. : C.S.F. Protein Various Ages. Acta Paediatr. Scand. 47: 1, 1958 (Suppl. 115).

11.

Marie, J. and See, G. : Acute Hypervitaminosis of the Infant—A Clinical and Biological Study . Am. J. Dis. Child. 87: 731, 1954.

12.

Fried, C.T. and Grand, M.J.H. : Hypervitaminosis A. Am. J. Dis. Child. 79: 475, 1950.

13.

Gerber, A. , Raab, A.P. and Sobel, A.E. : Vitamin A Poisoning in Adults. Am. J. Med. 16: 729, 1954.

14.

Persson, B. , Tunnell, R. and Ekengren, K. : Chronic Vitamin A Intoxication During the First Half Year of Life. Acta Paediatr. Scand. 54: 49, 1965.

15.

Caffey. J. : Chronic Poisoning Due to Excess of Vitamin A. Am. J. Roentgcnol. 65: 12, 1951.

16.

Woodward, W.K. , Miller, J.J. and Legant, O. : Acute and Chronic Hypervitaminosis in a 4-month-old-infant . J. Pediatr. 59: 260, 1961.

17.

The Use and Abuse of Vitamin A. Report of the Nutrition Committee . Can. Med. Assoc. J. 104: 521, 1971.