Erythema nodosum is an allergic response clinically associated with certain disease states, tuberculosis and streptococcal infec tions being most often incriminated. One family, including two siblings and their mother, developed erythema nodosum within one week of each other. The importance of primary tuberculosis as the etiology in the two sibs and the possibility of a double eti ology in one are stressed. This author also reviews this fascinating problem for us.
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References
1.
HeMman, Marvin D. and Skolnick, Marvin: Erythema nodosum and pulmonary tuberculosis in two sisters. Arch. Dermat.84: 402, Sept. 1961.
2.
Canfield, Craig J. and Loverholt, Edwin: Erythema ncsdosuan with bilateral hilar adenopathy, report of two cases. Med. Ann. D. C.33(5): 219, May 1964.
3.
Wedgwood, Ralph J.: Erythema nodosum. In the Textbook of Pediatrics , W. E. Nelson, ed. 8th Ed. Philadelphia, W. B. Saunders Company, 1964, p. 1001.
4.
Little, Joseph A. and Steigman, Alex J.: Erythema nodosum in primary histoplasmosis . JAMA173: 875, No. 8, June 25, 1960.
5.
Collis, W.R.F. : New conception of etiology of erythema nodosum . Quart. J. Med.1: 141, Jan. 1932.
Medeiros, Antone A., Marty, Sophocles D., Tash , Fred E. and Chin, Tom D. Y.: Erythema nodosum and erythema multiforme as clinical manifestations of histoplasmosis in a community outbreak. New Eng. J. Med.274: 415, No. 6, Feb. 24, 1966 .
8.
Pinsky, James Bernard and Stansifer , Philip D.: Erythema nodosum as the initial manifestation of leukemia. Arch. Dermat.89(3): 339, March 1964.
9.
Kerbel, Norman Carl: An unusual case of erythema nodosum. Canad. Med. Assn. J.83(15): 820, Oct. 8, 1960.
10.
Gordon, Harvey : Erythema nodosum, a review of 115 cases. Brit. J. Dermat.73: 393, Nov. 1961.
11.
Laurance, B. , Stone, D.G.H. et al.: Etiology of erythema, nodosum in children (a study by a group of pediatricians). Lancet281: 14, July 1, 1961.
12.
James, D. Geraint : Erythema nodosum. Brit. Med. J.1: 853, March 25, 1961.
13.
Telegdi, I. , Balint, J., Gorove , L., Mastuska, G., Pinter, G., Strebely, G. and Szeniczey, K.: Ob. servations on erythema nodosum tuberculosum in childhood. Z. Tuberk.115: 185, 1961.
14.
Rollof, S.I. : Course and prognosis in primary tuberculosis with erythema nodosum in children, in association with sulfathiozal (sulfonamide) in children, clinical investigation with special references to primary tuberculosis . Acta Tuberc. Scand. Suppl. 24, 1950.
15.
Booth, I.: Erythema nodosum. Amer. J. Dis. Child.85: 648, 1933.
16.
Doxiadis, S.A. : Etiology of erythema nodosum in children. Brit. Med. J.2: 844, 1949.
17.
Lorber, John : The changing etiology of erythema nodosum in children. Arch. Dis. Child.33: 137, 1958.
Holmdahl, K. : Course and prognosis in primary tuberculosis with erythema nodosum in children. Acta Tuberc. Scand. (supp. 22), pp. 1-179, 1950.
20.
Löfgren, S. : False positive seroreaction for syphilis in connection with erythema nodosum. Acta Dermat. Venereol.26: 243, Jan. 1946.
21.
Löfgren, S. : Studies on etiology and pathogenesis of erythema nodosum in 185 adult cases. Acta Med. Scand.124, Suppl. 174, 1946 .
22.
Löfgren, M. : Etiology and pathogenesis of erythema nodosum and erythema induratum. Nord. Med.46: 1069, July 1951.
23.
Sickerman, Mark J.: Septicemia due to group B Streptococcus, report of two siblings presenting with lesions resembling erythema nodosum . Pediatrics36: 937, 1965.