The objective of the study is to investigate the dietary inflammation index (DII) in children with celiac disease (CD) and its effect on clinic. This cross-sectional study involved 47 patients aged 5 to 18 diagnosed with CD, conducted from January 2024 to January 2025. Forty-seven patients with CD included in the study. The mean children-DII (c-DII) and energy consumption (e-c-DII) values of the study group were found to be 2.0 ± 1.0 and 2.7 ± 0.8, respectively. It was analyzed that c-DII and e-c-DII values were correlated significantly with tissue transglutaminase immunglobulin A and anti-endomysium antibody values. It was analyzed that the mean c-DII value was higher in patients with low waist circumference, mid-upper arm circumference, and skinfold thickness (<10% percentile), and the result was statistically significant. Anthropometric measurements, crucial indications of proper nutrition, were substantially correlated with the dietary inflammatory content in individuals with CD.
FurmanDCampisiJVerdinE, et al. Chronic inflammation in the etiology of disease across the life span. Nat Med. 2019;25(12):1822-1832.
2.
TilgHMoschenAR.Food, immunity, and the microbiome. Gastroenterology. 2015;148(6):1107-1119.
3.
ParzaneseIQehajajDPatrinicolaF, et al. Celiac disease: from pathophysiology to treatment. World J Gastrointest Pathophysiol. 2017;8(2):27-38.
4.
CavicchiaPPSteckSEHurleyTG, et al. A new dietary inflammatory index predicts interval changes in serum high-sensitivity C-reactive protein. J Nutr. 2009;139(12):2365-2372.
5.
SzypowskaAZatońskaKSzubaARegulska-IlowB.Dietary Inflammatory Index (DII)® and metabolic syndrome in the selected population of polish adults: results of the PURE Poland sub-study. Int J Environ Res Public Health. 2023;20(2):1056.
6.
KotemoriASawadaNIwasakiM, et al. Dietary inflammatory index is associated with inflammation in Japanese men. Front Nutr. 2021;8:604296.
7.
KęskaAPietrzakAIwańskaD.Use of the dietary inflammatory index to assess the diet of young physically active men. Int J Environ Res Public Health. 2022;19(11):6884.
8.
DehghanPNejatiMVahidF, et al. The association between dietary inflammatory index, dietary antioxidant index, and mental health in adolescent girls: an analytical study. BMC Public Health. 2022;22(1):1513.
9.
HébertJRShivappaNWirthMDHusseyJRHurleyTG.Perspective: the Dietary Inflammatory Index (DII)-lessons learned, improvements made, and future directions. Adv Nutr. 2019;10(2):185-195.
10.
HendricksonMAPittMB.Interpreting weight, height, and body mass index percentiles in the US Centers for Disease Control and Prevention growth charts-reply. JAMA Pediatr. 2022;176(4):425.
11.
HatipogluNOzturkAMaziciogluMMKurtogluSSeyhanSLokogluF.Waist circumference percentiles for 7- to 17-year-old Turkish children and adolescents. Eur J Pediatr. 2008;167(4):383-389.
12.
MrambaLNgariMMwangomeM, et al. A growth reference for mid upper arm circumference for age among school age children and adolescents, and validation for mortality: growth curve construction and longitudinal cohort study. BMJ. 2017;358:j3423.
13.
OzturkABudakNCicekBMaziciogluMMBayramFKurtogluS.Cross-sectional reference values for mid-upper arm circumference, triceps skinfold thickness and arm fat area of Turkish children and adolescents. Int J Food Sci Nutr. 2009;60(4):267-281.
14.
AddoOYHimesJH.Reference curves for triceps and subscapular skinfold thicknesses in US children and adolescents. Am J Clin Nutr. 2010;91(3):635-642.
15.
ShivappaNSteckSEHurleyTGHusseyJRHébertJR. Designing and developing a literature-derived, population-based dietary inflammatory index. Public Health Nutr. 2014;17(8):1689-1696.
16.
MartiniNKara TahhanNAldarwishMSMahmoudJ.Rectal prolapse as a manifestation of inflammatory bowel disease with celiac disease in a 2-year-old male: a rare case report. Ann Med Surg (Lond). 2023;85(4):1235-1239.
17.
LeonardMMWeirDCDeGrooteM, et al. Value of IgA tTG in predicting mucosal recovery in children with celiac disease on a gluten-free diet. J Pediatr Gastroenterol Nutr. 2017;64(2):286-291.
18.
TaşkınDGAtaA.The value of mid-upper arm circumference for malnutrition screening in pediatric celiac disease. Adv Clin Exp Med. 2023;32(12):1369-1375.
19.
LamersCRde RoosNMWittemanBJM. The association between inflammatory potential of diet and disease activity: results from a cross-sectional study in patients with inflammatory bowel disease. BMC Gastroenterol. 2020;20(1):316.
20.
AlshwaikiANakhalRMHDSNahleAAHamdarHMartiniNMahmodJ.Infantile inflammatory bowel disease in three Syrian infants: a case series. J Med Case Rep. 2024;18(1):160.
21.
MhannaAMartiniNHmaydooshG, et al. The correlation between gut microbiota and both neurotransmitters and mental disorders: a narrative review. Medicine. 2024;103(5):e37114.
22.
SilvesterJAKuradaSSzwajcerAKellyCPLefflerDADuerksenDR.Tests for serum transglutaminase and endomysial antibodies do not detect most patients with celiac disease and persistent villous atrophy on gluten-free diets: a meta-analysis. Gastroenterology. 2017;153(3):689-701.e1.
23.
SamascaGSurGLupanIDeleanuD.Gluten-free diet and quality of life in celiac disease. Gastroenterol Hepatol Bed Bench. 2014;7(3):139-143.
24.
HenriquesHKFFonsecaLMde AndradeKS, et al. Gluten-free diet reduces diet quality and increases inflammatory potential in non-celiac healthy women. J Am Nutr Assoc. 2022;41(8):771-779.
25.
AuricchioRCalabreseIGalatolaM, et al. Author correction: gluten consumption and inflammation affect the development of celiac disease in at-risk children. Sci Rep. 2022;12(1):8157.
