Two Teenagers With New-Onset,Ascending Weakness With Progressive Neurologic Deficits

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References

Lallas

Desai

Wernicke encephalopathy in children and adolescents. World J Pediatr. 2014;10(4):293-298. doi:10.1007/s12519-014-0506-9.

Morrissey

Ali

John

Pawar

McQuade

EA.

Beriberi neuropathy mimicking Guillian-Barre syndrome in a teenager with food restriction: a case report. Cureus. 2022;14(1):e21417. doi:10.7759/cureus.21417.

Mrowicka

Mrowicki

Dragan

Majsterek

The importance of thiamine (vitamin B1) in humans. Biosci Rep. 2023;43(10):BSR20230374. doi:10.1042/BSR20230374.

Wiley

Gupta

Vitamin B1 (Thiamine) Deficiency. Treasure Island, FL: StatPearls Publishing; 2023. Accessed May 6, 2025. Available at: https://www.ncbi.nlm.nih.gov/books/NBK537204/.

Shible

Ramadurai

Gergen

Reynolds

PM.

Dry Beriberi due to thiamine deficiency associated with peripheral neuropathy and Wernicke’s encephalopathy mimicking Guillain-Barré syndrome: a case report and review of the literature. Am J Case Rep. 2019;20:330-334. doi:10.12659/AJCR.914051

Shahrizaila

Lehmann

Kuwabara

Guillain-Barré syndrome. Lancet. 2021;397(10280):1214-1228. doi:10.1016/S0140-6736(21)00517-1.

Lineback

Brahmbhatt

Abbott

A case of non-alcoholic Wernicke’s encephalopathy and dry Beri-Beri with GI involvement following a period of prolonged gastrointestinal illness (1266). Gen Neurol Clin Case Rep. 2020;94(suppl 15). doi:10.1212/WNL.94.15_supplement.126.

Briani

Dalla Torre

Citton

, et al. Cobalamin deficiency: clinical picture and radiological findings. Nutrients. 2013;5(11):4521-4539. doi:10.3390/nu5114521.

Stabler

SP.

Clinical practice. Vitamin B12 deficiency. N Engl J Med. 2013;368(2):149-160. doi:10.1056/NEJMcp1113996.

10.

Oudman

Wijnia

Bidesie

, et al. Pediatric Wernicke encephalopathy: a systematic review. Pediatric Reports. 2025;17(1):15. doi:10.3390/pediatric17010015.

11.

Xing

Wernicke encephalopathy: a mini review of the clinical spectrum, atypical manifestations, and diagnostic challenges. Front Neurol. 2025;16:1566366. doi:10.3389/fneur.2025.1566366.

12.

Yuki

Hartung

HP.

Guillain-Barré syndrome. N Engl J Med. 2012;366(24):2294-2304. doi:10.1056/NEJMra1114525.

13.

Elendu

Osamuyi

Afolayan

, et al. Clinical presentation and symptomatology of Guillain-Barré syndrome: a literature review. Medicine. 2024;103(30):e38890. doi:10.1097/MD.0000000000038890.

14.

Slagle

Meece

Foster

Campbell

Tong

Drake

Altered mental status and cardiac failure due to thiamine deficiency in an overweight teen. Pediatrics. 2024;153(4):e2022060958. doi:10.1542/peds.2022-060958.

15.

Rakotoambinina

Hiffler

Gomes

Pediatric thiamine deficiency disorders in high-income countries between 2000 and 2020: a clinical reappraisal. Ann N Y Acad Sci. 2021;1498(1):5757-5776. doi:10.1111/nyas.14669.