Serum Sickness and Serum Sickness-Like Reactions Presenting to Pediatric Hospital

Lawley TJ Bielory L Gascon P , et al. A prospective clinical and immunologic analysis of patients with serum sickness. N Engl J Med. 1984;311:1407.

Heckbert SR Stryker WS Coltin KL Manson JE Platt R. Serum sickness in children after antibiotic exposure: estimates of occurrence and morbidity in a health maintenance organization population. Am J Epidemiol. 1990;132(2):336-342.

Del Pozzo-Magaña BR Abuzgaia A Murray B Rieder MJ Lazo-Langner A. Paediatric serum sickness-like reaction: a 10-year retrospective cohort study. Paediatr Child Health. 2021;26(7):428-435.

Chiong FJ Loewenthal M Boyle M Attia J. Serum sickness-like reaction after influenza vaccination. BMJ Case Rep. 2015;2015:bcr2015211917.

Tsabouri S Atanaskovic-Markovic M. Skin eruptions in children: drug hypersensitivity vs viral exanthema. Pediatr Allergy Immunol. 2021;32(5):824-834.

Zhang Z Xiang Y Wang B , et al. Intestinal mucosal permeability of children with cefaclor-associated serum sickness-like reactions. Eur J Pediatr. 2013;172(4):537-543.

Yorulmaz A Akın F Sert A , et al. Demographic and clinical characteristics of patients with serum sickness-like reaction. Clin Rheumatol. 2018;37(5):1389-1394.

Vial T Pont J Pham E Rabilloud M Descotes J. Cefaclor-associated serum sickness-like disease: eight cases and review of the literature. Ann Pharmacother. 1992;26(7-8):910-914.

Joubert GI Hadad K Matsui D Gloor J Rieder MJ. Selection of treatment of cefaclor-associated urticarial, serum sickness-like reactions and erythema multiforme by emergency pediatricians: lack of a uniform standard of care. Can J Clin Pharmacol. 1999;6(4):197-201.

Grammer LC. Cefaclor serum sickness. JAMA. 1996;275:1152.

Khan DA Banerji A Blumenthal KG , et al. Drug allergy: a 2022 practice parameter update. Practice guideline. J Allergy Clin Immunol. 2022;150(6):1333-13393.

Tatum AJ Ditto AM Patterson R. Severe serum sickness-like reaction to oral penicillin drugs: three case reports. Ann Allergy Asthma Immunol. 2001;86(3):330-334.

Delli Colli L Gabrielli S Abrams EM , et al. Differentiating between β-lactam-induced serum sickness-like reactions and viral exanthem in children using a graded oral challenge. J Allergy Clin Immunol Pract. 2021;9(2):916-921.

Fernandez E Koo G Stone C , et al. Optimal timing of graded oral challenge in children with serum sickness like reactions to antibiotics. J Allergy Clin Immunol. 2024;153(2):AB228.

Nelson WE. Nelson textbook of pediatrics. 21st ed. Amsterdam, the Netherlands: Elsevier. 2019; Chap. 175.

Fleisher G Ludwig S. Textbook of pediatric emergency medicine. 8th ed. Alphen aan den Rijn, the Netherlands: Wolters Kluwer Health. 2021; Chap. 84; p. 1816.