Less Invasive Surfactant Administration for the Treatment of Neonatal Respiratory Distress Syndrome Combined With Noninvasive Ventilation in Anhui Province,China: A Retrospective Cohort Study
Restricted accessResearch articleFirst published online October, 2023
Less Invasive Surfactant Administration for the Treatment of Neonatal Respiratory Distress Syndrome Combined With Noninvasive Ventilation in Anhui Province,China: A Retrospective Cohort Study
The less invasive surfactant application (LISA) technology has been widely used to manage breathing in premature infants. Premature infants with respiratory distress syndrome (RDS) were retrospectively analyzed and divided into 2 groups according to the drug delivery methods used: LISA versus traditional pulmonary surfactant injection (INSURE). The decrease of transcutaneous saturation (TcSO2) and heart rate during surfactant delivery in the LISA group was higher than that in the INSURE group (P < .05). Between the 2 groups, there was no significant difference in the change in partial pressure of oxygen/fraction of inspired oxygen value before and after drug delivery; second-use pulmonary surfactant; noninvasive ventilation (NIV) failure rate; incidence of some complications; duration of NIV use; hospitalization time; and mortality (P > .05). However, the incidence of bronchopulmonary dysplasia (BPD) in the LISA group was lower than that in the INSURE group (P < .05). The clinical efficacy of LISA combined with the NIV treatment in premature infants with RDS was clear, and this treatment could reduce the incidence of BPD.
SweetDGCarnielliVGreisenG, et al. European consensus guidelines on the management of respiratory distress syndrome–2019 update. Neonatology. 2019;115(4):432-450.
2.
HertingEKribsAHärtelC, et al. Two-year outcome data suggest that less invasive surfactant administration (LISA) is safe. Results from the follow-up of the randomized controlled AMV (avoid mechanical ventilation) study. Eur J Pediatr. 2020;179(8):1309-1313.
3.
ConlonSMOsborneABodieJMaraschJRyanRMGlennT. Introducing less-invasive surfactant administration into a level IV NICU: a quality improvement initiative. Children. 2021;8(7):580.
4.
SteinbauerPKlebermass-SchrehofKCardonaF, et al. Impact of a multifactorial educational training on the management of preterm infants in the Central-Eastern European region. Front Pediatr. 2021;9:700226.
5.
SakonidouSDhaliwalJ. The management of neonatal respiratory distress syndrome in preterm infants (European Consensus Guidelines—2013 update). Arch Dis Child Educ Pract Ed. 2015;100(5):257-259.
6.
VerderHAgertoftLAlbertsenP, et al. Surfactant treatment of newborn infants with respiratory distress syndrome primarily treated with nasal continuous positive air pressure. A Pilot Study. Ugeskr Laeger. 1992;154(31):2136-2139.
7.
KribsAPillekampFHuenselerCVierzigARothB. Early administration of surfactant in spontaneous breathing with nCPAP: feasibility and outcome in extremely premature infants (postmenstrual age≤ 27 weeks). Paediatr Anaesth. 2007;17(4):364-369.
8.
KurepaDPerveenSLipenerYKakkilayaV. The use of less invasive surfactant administration (LISA) in the United States with review of the literature. J Perinatol. 2019;39(3):426-432.
9.
Márquez IsidroESanchez LunaMRamos-NavarroC. Long-term outcomes of preterm infants treated with less invasive surfactant technique (LISA). J Matern Fetal Neonatal Med. 2021;34(12):1919-1924.
10.
BhayatSKaurAPremadevaIReynoldsPGowdaH. Survey of less invasive surfactant administration in England, slow adoption and variable practice. Acta Paediatr. 2020;109(3):505-510.
11.
BuyuktiryakiMAlarcon-MartinezTSimsekGK, et al. Five-Year single center experience on surfactant treatment in preterm infants with respiratory distress syndrome: LISA vs INSURE. Early Hum Dev. 2019;135:32-36.
12.
MaiwaldCANeubergerPFranzAREngelCVochemMPoetsCF. Clinical evaluation of an application aid for less-invasive surfactant administration (LISA). Arch Dis Child Fetal Neonatal Ed. 2021;106(2):211-214.
13.
ListaGBresestiIFabbriL. Is less invasive surfactant administration necessary or “only” helpful or just a fashion?Am J Perinatol. 2018;35(06):530-533.
14.
SzczapaTHożejowskiRKrajewskiP; Study Group. Implementation of less invasive surfactant administration in clinical practice—experience of a mid-sized country. PLoS ONE. 2020;15(7):e0235363.
15.
MaiwaldCANeubergerPFranzAR, et al. Catheter insertion depths in less-invasive surfactant administration. Arch Dis Child fetal Neonatal Ed. 2022;107:222-224.
16.
HertingEHärtelCGöpelW. Less invasive surfactant administration (LISA): chances and limitations. Arch Dis Child Fetal Neonatal Ed. 2019;104(6):F655-F659.
17.
RigoVLefebvreCBrouxI. Surfactant instillation in spontaneously breathing preterm infants: a systematic review and meta-analysis. Eur J Pediatr. 2016;175(12):1933-1942.
18.
GortnerLSchüllerSSHertingE. Review demonstrates that less invasive surfactant administration in preterm neonates leads to fewer complications. Acta Paediatr. 2018;107(5):736-743.
19.
LauCSChamberlainRSSunS. Less invasive surfactant administration reduces the need for mechanical ventilation in preterm infants: a meta-analysis. Glob Pediatr Health. 2017;4:2333794X17696683.
20.
PareekPDeshpandeSSuryawanshiP, et al. Less invasive surfactant administration (LISA) vs. Intubation surfactant extubation (InSurE) in preterm infants with respiratory distress syndrome: a pilot randomized controlled trial. J Trop Pediatr. 2021;67(4):fmab086.
21.
Ramos-NavarroCSánchez-LunaMZeballos-SarratoSGonzález-PachecoN. Three-year perinatal outcomes of less invasive beractant administration in preterm infants with respiratory distress syndrome. J Matern Fetal Neonatal Med. 2020;33(16):2704-2710.
22.
ShettySEganHCornuaudPKulkarniADuffyDGreenoughA. Less invasive surfactant administration in very prematurely born infants. AJP Rep. 2021;11(3):e119-e122.
23.
LanghammerKRothBKribsAGöpelWKuntzLMiedanerF. Treatment and outcome data of very low birth weight infants treated with less invasive surfactant administration in comparison to intubation and mechanical ventilation in the clinical setting of a cross-sectional observational multicenter study. Eur J Pediatr. 2018;177(8):1207-1217.
24.
HärtelCPaulPHankeK, et al. Less invasive surfactant administration and complications of preterm birth. Sci Rep. 2018;8(1):1-7.
25.
Aldana-AguirreJCPintoMFeatherstoneRMKumarM. Less invasive surfactant administration versus intubation for surfactant delivery in preterm infants with respiratory distress syndrome: a systematic review and meta-analysis. Arch Dis Child Fetal Neonatal Ed. 2017;102(1):F17-F23.
26.
KaniewskaUGulczyńskaE. The influence of the technique of surfactant administration (LISA INSURE) on the outcomes of respiratory distress syndrome treatment in preterm infants. J Mother Child. 2019;23(3):163-171.
27.
SilahliMTekinM. The comparison of LISA and INSURE techniques in term of neonatal morbidities and mortality among premature infants. Acta Biomed. 2020;91(4):e2020189.
28.
Queliz PenaTPerezJCorriganM. A comparison of LISA versus insure: a single center experience. J Neonatal Perinatal Med. 2021;14:503-509.
29.
HanTLiuHZhangH, et al. Minimally invasive surfactant administration for the treatment of neonatal respiratory distress syndrome: a multicenter randomized study in China. Front Pediatr. 2020;8:182.
