Ibuprofen-Induced Liver Injury in an Adolescent Athlete

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References

Rubenstein JH , Laine L. Systematic review: the hepatoxicity of non-steroidal anti-inflammatory drugs. Aliment Pharmacol Ther. 2004;20:373-380.

Fries JF , Miller SR , Spitz PW , Williams CA , Hubert HB , Bloch DA Identification of patients at risk for gastropathy associated with NSAID use . J Rheumatol. Suppl. 1990;20:12-19.

Rostom A. , Goldkind L. , Laine L. Nonsteroidal anti-inflammatory drugs and hepatic toxicity: a systematic review of randomized controlled trials in arthritis patients. Clin Gastroenterol Hepatol. 2005;3:489-498.

Elkrief L. , Chryssostalis A. , Moachon L. , et al. Severe cholestatic hepatitis associated with a Stephens-Johnson syndrome after taking ibuprofen. Gastroenterol Clin Biol. 2007;31:1043-1045.

Javier Rodriguez-Gonzalez F. , Montero JL , Puente J. , et al. Orthotopic liver transplantation after subacute liver failure induced by therapeutic doses of ibuprofen. Am J Gastroenterol. 2002;97:2476-2477.

Laurent S. , Rahier J. , Geubel A. , Lerut J. , Horsmans Y. Subfulminant hepatitis requiring liver transplantation following ibuprofen overdose. Liver. 2000;20:93-94.

Taghian M. , Tran Ta T. , Bresson-Hadni S. , Menget A. , Felix S. , Jacquemin E. Acute vanishing bile duct syndrome after ibuprofen therapy in a child. J Pediatr. 2004;145:273-276.

Andrade RJ , Lucena MI , Garcia-Cortes M. , Garcia-Ruiz E. , Fernandez-Bonilla E. , Vasquez L. Chronic hepatitis C, ibuprofen, and liver damage. Am J Gastroenterol . 2002;97:1854-1855.

Kaplowitz N. Idiosyncratic drug hepatotoxicity. Nat Rev Drug Discov. 2005;4:489-499.

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Daly AK , Aithal GP , Leathart JB , Swainsbury RA , Dang TS , Day CP Genetic susceptibility to diclofenac-induced hepatoxicity: contribution of UGT2B7, CYP2C8, and ABCC2 genotypes. Gastroenterology. 2007;132:272-281.