Virchow R. Gesammalte Abhandlungen zur wissenschaftlichen Medtzin. Medinger Sohn. 1856:219-732.
2.
Federman DG, Kirsner RS. An update on hypercoagulable disorders. Arch Intern Med. 2001;161:1051-1056.
3.
Seligsohn U, Lubetsky A. Genetic susceptibility to venous thrombosis. N Engl J Med. 2001;344:1222-1231.
4.
Andrew M, David M, Adams M, et al.Venous thromboembolic complications (VTE) in children: First analyses of the Canadian Registry of VTE. Blood. 1994;83:1251-1257.
5.
Genetic susceptibility to venous thrombosis. N Engl J Med. 2001;344:1222-1231.
6.
Miller R, Kodish E. Causes of thrombosis. Contemp Pediatr. 1996;13:79-97.
7.
Nowak-Gottl U, von Kries R, Gobel U. Neonatal symptomatic thromboembolism in Germany: Two-year survey. Arch Dis Child Fetal Neonatal Ed. 1997;76:F163-F167.
8.
Schmidt B, Andrew M. Neonatal thrombosis: Report of a prospective Canadian and international registry. Pediatrics. 1995;96(5 Pt 1):939-943.
9.
van Ommen CH, Heijboer H, Buller HR, et al.Venous thromboembolism in childhood: A prospective two-year registry in The Netherlands. J Pediatr. 2001;139:676-681.
10.
Andrew M, Paes B, Johnston M. Development of the hemostatic system in the neonate and young infant. Am J Pediatr Hematol Oncol. 1990;12:95-104.
11.
Wenstrom K, ed. Danforth’s Obstetrics and Gynecology, ed 8.Philadelphia: Lippincott, Williams Wilkins; 1999:340.
12.
Crowther MA, Kelton JG. Congenital thrombophilic states associated with venous thrombosis: A qualitative overview and proposed classification system. Ann Intern Med. 2003;138:128-134.
13.
Mateo J, Oliver A, Borrell M, et al.Laboratory evaluation and clinical characteristics of 2,132 consecutive unselected patients with venous thromboembolism—results of the Spanish Multicentric Study on Thrombophilia (EMET-Study). Thromb Haemost. 1997;77:444-451.
14.
Ridker PM, Hennekens CH, Miletich JP. G20210A mutation in prothrombin gene and risk of myocardial infarction, stroke, and venous thrombosis in a large cohort of US men. Circulation. 1999;99:999-1004.
15.
Ben-Tal O, Zivelin A, Seligsohn U. The relative frequency of hereditary thrombotic disorders among 107 patients with thrombophilia in Israel. Thromb Haemost. 1989;61:50-54.
16.
Wells PS, Blajchman MA, Henderson P, et al.Prevalence of antithrombin deficiency in healthy blood donors: A cross-sectional study. Am J Hematol. 1994;45:321-324.
17.
Tait RC, Walker ID, Perry DJ, et al.Prevalence of antithrombin deficiency in the healthy population. Br J Haematol. 1994;87:106-112.
18.
Tait RC, Walker ID, Reitsma PH, et al.Prevalence of protein C deficiency in the healthy population. Thromb Haemost. 1995;73:87-93.
19.
Sakata T, Kario K, Katayama Y, et al.Studies on congenital protein C deficiency in Japanese: prevalence, genetic analysis, and relevance to the onset of arterial occlusive diseases. Semin Thromb Hemost. 2000;26:11-16.
20.
Pabinger I, Brucker S, Kyrle PA, et al.Hereditary deficiency of antithrombin III, protein C and protein S: Prevalence in patients with a history of venous thrombosis and criteria for rational patient screening. Blood Coagul Fibrinolysis. 1992;3:547-553.
Dahlback B, Hildebrand B. Inherited resistance to activated protein C is corrected by anticoagulant cofactor activity found to be a property of factor V. Proc Natl Acad Sci USA. 1994;91:1396-1400.
23.
Rodeghiero F, Tosetto A. Activated protein C resistance and factor V Leiden mutation are independent risk factors for venous thromboembolism. Ann Intern Med. 1999;130:643-650.
24.
Cattaneo M. Hyperhomocysteinemia, atherosclerosis and thrombosis. Thromb Haemost. 1999;81:165-176.
25.
Ray JG. Meta-analysis of hyperhomocysteinemia as a risk factor for venous thromboembolic disease. Arch Intern Med. 1998;158:2101-2106.
26.
Kluijtmans LA, van den Heuvel LP, Boers GH, et al.Molecular genetic analysis in mild hyperhomocysteinemia: A common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease. Am J Hum Genet. 1996;58:35-41.
27.
Jacques PF, Bostom AG, Williams RR, et al.Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations. Circulation. 1996;93:7-9.
28.
van Guldener C, Stehouwer CD. Hyperhomocysteinemia, vascular pathology, and endothelial dysfunction. Semin Thromb Hemost. 2000;26:281-289.
29.
Werstuck GH, Lentz SR, Dayal S, et al.Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways. J Clin Invest. 2001;107:1263-1273.
30.
Tormene D, Simioni P, Prandoni P, et al.The incidence of venous thromboembolism in thrombophilic children: A prospective cohort study. Blood. 2002;100:2403-2405.
