Sage Journals: Discover world-class research

Abstract

Objective:

To assess the effects of psychological, psychosocial, educational and alternative interventions on mental health outcomes of Indigenous adult populations in Australia, Canada, New Zealand and the United States and the Indigenous involvement and content in each study.

Methods:

We systematically searched databases, key journals and gray literature, for records until June 2020. Eligible studies were in English or French and examined the impact of interventions on mental health outcomes including anxiety disorders, posttraumatic stress disorder, depression, psychological distress or stress for Indigenous adults (⩾16 years). Data were extracted using a modified Cochrane Data Extraction Form and the Template for Intervention Description and Replication. Quality was evaluated using the Effective Public Health Practice Project quality assessment form.

Results:

In total, 21 studies were eligible, comprising 8 randomized controlled trials, 10 single-group pre–post studies and 3 pre–post studies with comparison groups. Twenty studies had Indigenous individuals or organizations involved in some decision-making capacity, though extent of involvement varied widely. In total, 9 studies were rated moderate and 12 weak in the Effective Public Health Practice Project quality assessment. Eight studies measuring depression, three measuring posttraumatic stress disorder, three measuring psychological distress and two measuring stress showed statistically significant improvements following the intervention.

Conclusion:

A wide range of interventions demonstrated mental health improvements. However, it is difficult to draw generalizable conclusions on intervention effectiveness, given heterogeneity among studies. Studies should employ a thorough assessment of the Indigenous involvement and content of their interventions for reporting and for critical consideration of the implications of their research and whether they address Indigenous determinants of mental health.

Keywords

Indigenous peoples mental health systematic review

Introduction

Indigenous peoples have been displaced from their ancestral lands (United Nations, 2009). Vital cultural connections to the land were and continue to be disrupted, creating ‘near total psychological, physical and financial dependency on the state’ (Alfred, 2009: 42), inhibiting Indigenous self-governance, as well as creating an experience of collective, historical and intergenerational trauma which contribute to adverse health outcomes (Alfred, 2009; Kirmayer et al., 2000; Nielsen and Robyn, 2003; O’Neill et al., 2018). Consequently, Indigenous populations in colonial states such as Canada, the United States, Australia and New Zealand often have disproportionately high rates of mental illnesses. Off-reserve First Nations and Métis populations have a higher prevalence of mood and anxiety disorders compared to non-Indigenous populations (Rotenberg, 2016; Statistics Canada, 2016) which has also been observed in American Indian and Alaska Native populations (Bassett et al., 2014; Beals et al., 2005). Māori adults in New Zealand also have a higher prevalence of anxiety and mood disorders and an increased likelihood of psychological distress compared to non-Māori adults (Baxter et al., 2006; Ministry of Health—Manatu Hauora, 2020a) similar to Aboriginal and Torres Strait Islander People in Australia (Calma et al., 2017; Markwick et al., 2014). In turn, calls for political changes have been made, including the return of Indigenous lands, self-determination, self-governance and community development for the improvement of mental, physical, spiritual health and the economic well-being of Indigenous peoples (Alfred, 2009; Kirmayer et al., 2000; Tuck and Yang, 2012).

Despite calls for structural changes to address root causes of mental health disparities between Indigenous and non-Indigenous populations (Australian Government, 2019; Ministry of Health—Manatu Hauora, 2020b; Public Health Agency of Canada, 2020; US Department of Health and Human Services, 2020), programs have focused on ameliorating individual symptoms using psychological, psychosocial, educational or alternative interventions. Such approaches to mental health have then been critiqued for their harmful colonial perspectives or cultural ‘inappropriateness’, so instead, culturally sensitive, culturally competent, to culturally safe approaches have been developed (Brascoupé and Waters, 2009; Curtis et al., 2019; Wilson et al., 2013). Furthermore, cultural healing and continuity, connection to land, inclusion of community strengths and leadership are known to be protective and promotive elements of mental health for Indigenous peoples (Auger, 2016; First Nations Health Authority, 2018; Kelly et al., 2009; MacDonald et al., 2013). As a wide array of mental health interventions exist, it is important to summarize information and identify strengths and limitations of current research to inform future program and intervention planning.

While existing systematic reviews have examined mental health interventions for Indigenous populations, the most recent publications in these reviews are from 2015 (Antonio and Chung-Do, 2015; Leske et al., 2016; Pollok et al., 2018; Pomerville et al., 2016). Furthermore, none have conducted an extensive assessment to examine Indigenous involvement and content. Therefore, our review examines (1) the effect of psychological, psychosocial, educational and alternative interventions on mental health outcomes for adult Indigenous populations and (2) the cultural content and Indigenous involvement in the research and intervention processes. Our review leads to a discussion on considerations for research on mental health interventions for Indigenous populations.

Methods

Information sources and search strategy

The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines (Liberati et al., 2009) and the protocol (PROSPERO registration # CRD42018087994) were followed. A systematic search was conducted in MEDLINE, Embase, PsycINFO, CINAHL, Cochrane and Scopus as well as in the Bibliography of Native North Americans and Native Health Database. Gray literature was identified through Grey Matters and additional articles from a manual search of the International Journal of Indigenous Health, Journal of Indigenous Wellbeing, Journal of Indigenous Research, AlterNative: An International Journal of Indigenous Peoples and American Indian Quarterly. Controlled vocabulary was identified along with keywords to search for mental health outcomes of interest AND interventions AND Indigenous populations (Supplemental Table S1). After consulting a librarian, the search was completed on 1 June 2020.

Screening and eligibility

Covidence was used to screen titles and abstracts, and for the full-text review, successively. Screening was done independently by two reviewers, and conflicts were resolved by a third reviewer and through discussions. If the full text of an eligible abstract could not be located, its authors were contacted to confirm whether an article was published. If authors did not respond within 2 weeks, the abstract was excluded.

Titles and abstracts were excluded if they did not include (1) Indigenous people from Canada, the United States, New Zealand or Australia; (2) a mental health intervention; and (3) mental health outcome(s). Eligible studies for full-text screening were experimental, quasi-experimental or observational; written in English or French; and examined how an intervention impacted the following mental health outcomes: anxiety disorders, posttraumatic stress disorder (PTSD), depression, psychological distress or stress. If these studies also included general and strength-based mental health outcomes, these were extracted. Study participants’ age were greater or equal to 16 years or 16 years on average. The research setting was limited to Canada, the United States, New Zealand or Australia which share similar histories of colonization and racism against Indigenous peoples (Paradies, 2016). Studies employing psychological, psychosocial, educational, alternative interventions or cultural interventions were included. Solely pharmacological interventions were excluded.

Data collection

Data were extracted by two authors independently using the Cochrane data collection form for randomized controlled trials (RCTs) and non-RCTs (Higgins and Green, 2011). Discrepancies were resolved by a third reviewer and through discussions. Bibliographic information, study design, setting and study period, recruitment, eligibility criteria, sample size, and response and follow-up rates were collected. The outcomes, measurement tools and relevant details of the analysis were extracted. The interventions were described using the Template for Intervention Description and Replication (TIDieR) checklist (Hoffmann et al., 2014). The intervention name; descriptions of the rationale, materials and procedures used; intervention facilitators and research training; how and where the intervention was executed; and its duration and frequency were extracted. Additionally, intervention tailoring and modification as well as fidelity and adherence were summarized.

Risk of bias assessment

The studies were appraised using the Effective Public Health Practice Project (EPHPP) quality assessment tool (Armijo-Olivo et al., 2012) by two independent reviewers, and conflicts were resolved with a third reviewer and through discussions (Supplemental Table S2). Assessment criteria were selection bias, study design, confounding, blinding, data collection, and withdrawal and dropouts. Sex, age, socio-economic status and co-morbidities were defined a priori as confounders. Each criterion was rated weak, moderate or strong. For the global rating, studies were weak if they had two or more criteria rated weak, they were rated moderate if they had one weak rating, or strong if they had no weak ratings.

Results synthesis

Qualitative synthesis was used to report the findings of the studies.

Assessment of Indigenous involvement and content

An assessment of Indigenous involvement and content in the studies was completed independently by two authors and information extracted was supported by prior literature (Huria et al., 2019). We assessed whether Indigenous individuals or groups had decision-making responsibilities at the study design level and were involved in conducting research activities or implementing the intervention. We also assessed whether the studies were specific to an Indigenous population(s) and had considered the population’s diversity and had general or localized Indigenous knowledge included in the intervention or research processes.

Results

Study selection

The search resulted in 67,207 articles and after removing duplicates, 57,826 articles remained. A total of 57,523 articles were excluded based on title and abstract review, and 303 full-text articles were assessed for eligibility. Of these, 283 articles were excluded based on the eligibility criteria (Figure 1) resulting in 21 articles for our review.

Figure 1.

PRISMA flow diagram of the study selection.

Characteristics of included studies

Study characteristics are described in Table 1. Of the 21 studies included, there were 8 RCTs, 10 single-group pre–post designs and 3 pre–post designs with comparison groups. Studies were conducted in the United States (n = 9), Australia (n = 6), Canada (n = 3) and New Zealand (n = 3) and were published between 2009 and 2020. Sample sizes ranged from 10 to 365. Only nine studies reported response rates ranging from 9% to 97% and 19 studies had follow-up rates between 16% and 100%.

Table 1.

Characteristics of included studies.

Author	Study design	Study location, period	Recruitment	Eligibility criteria	Sample size	Outcomes	Response rate	Follow-up rate
Beckstead et al. (2015)	Pre–post	Phoenix, US 2010–2013	Residential treatment center	AI/AN, admitted and discharged from youth center for substance use disorders	N = 229	Psychological distress	NR	211/229 = 92%
Bennett et al. (2014)	Pre–post	New Zealand Period NR	Case managers provided study information	Māori, aged ⩾18 years, with depressive symptoms as primary presenting issue	N = 16	Depression	NR	Post-Tx: 14/16 = 88%, 6-month FU: 15/16 = 94%
Bowen et al. (2020)	Pre–post^a	Rocky Mountain West, upper Great Plains and Alaska, Western US Period NR	NA Participants were primary care clinic patients	AI/AN, aged ⩾18 years, untreated active depressive episode; no bipolar disorder, psychosis or moderate to severe cognitive impairment, set for depression Tx	N = 345	Depression	NA	First FU ⩽ 4 weeks = 54.4%, FU ⩾ 2 contacts = 59.7%
Brave Heart et al. (2020)	Pilot clinical trial, RCT	US Period NR	Participants approached at two tribal sites	AI, aged ⩾18 years, positive screen for depression, no serious mental disorders or impaired cognitive ability or acute suicidal/homicidal risk or severe substance use disorder	N = 52 IPT = 23, HTUG + IPT = 29	Depression, PTSD	NR	37/52 = 71% IPT: 15/23 = 65%, HTUG + IPT: 22/29 = 76%
Dickerson et al. (2014)	Pre–post	Los Angeles County, US 2011–2012	Flyers in clinics and organizations serving AI/AN	AI/AN, aged ⩾18 years, meet current or past substance use disorder DSM criteria, no psychiatric or medical conditions preventing participation	N = 10	Psychiatric symptoms, psychiatric status	NR	Mid-point FU: 8/10 = 80%, Post-Tx: 5/10 = 50%
Gray et al. (2010)	RCT	Southwestern US 2002–2004	Announcements, flyers on community bulletin board, tribal newspaper, wellness fair booth, door-to-door, word of mouth	Female tribal members, aged 18–50 years; regardless of health status, substance use or depression status	N = 268 Tx group = 126, Ctrl group = 142	Depression, self-esteem	268/764 = 35%	6-month FU: 89/126 = 71% Tx group, 92/142 = 65% Ctrl group
Hatcher et al. (2016)	Double consent Zelen RCT	New Zealand 2009–2012	Hospital emergency department patients	Māori, aged ⩾18 years, emergency visit after episode of self-harm	N = 365 Tx group = 182, Ctrl group = 183	Anxiety, depression, sense of belonging, hopelessness	167/497 = 34%	1-year FU: 66/95 = 69% Tx group, 48/72 = 67% Ctrl group
Korn et al. (2009)	RCT	Western Washington State, US Period NR	AI/AN tribal liaison and clinical coordinator in tribal health program, health fairs, word-of-mouth	AI/AN, phone access, primary caregiver of family member with dementia for ⩾6 months ⩾4 hours care/day, in community for ⩾6 months	1.3 N = 42 Tx group = 21, Ctrl group = 21	Depressive symptoms, stress, mental health	42/54 = 78%	38/42 = 90%
Mathieson et al. (2012)	Pre–post	New Zealand Period NR	Clinical judgment, case-finding Help Assessment Tool	Māori, aged 18–65 years, K10 score ⩽ 35, distressed but not suicidal	N = 16	Psychological distress	NR	7/16 = 44%
Nagel et al. (2009)	RCT	Three remote island communities, Northern Territory, Australia 2004–2007	Referred by local mental health workers	Patients of health center with chronic mental illness ⩾6 months or ⩾1 relapse	1.4 N = 49 Tx group = 24, Ctrl group = 25	Psychological distress, mental illness	49/79 = 62%	6-, 12- and 18-month FU: 22/24 = 92%, 21/24 = 88%, 17/24 = 71% Tx group 22/25 = 88%, 21/25 = 84%, 18/25 = 72% Ctrl group
Pearson et al. (2019)	RCT	Pacific Northwest, US Period NR	Recruitment material in tribal service centers, colleges, fairs, churches, powwows	Female AI/AN, aged ⩾18 years, ⩾2 days heavy drinking in past year or use of illicit drugs in past 3 months, willingness to abstain during therapy, PTSD symptoms, self-reported sexual activity in past year	1.5 N = 73 Tx group = 37, Ctrl group = 36	PTSD symptoms	73/87 = 84%	Immediate post-Tx: 6/37 = 16% Tx group, 12/36 = 33% Ctrl group 3-month post-Tx: 21/37 = 57% Tx group, 19/36 = 53% Ctrl group
Sabbioni et al. (2018)	Pre–post	Perth, Western Australia 2014–2016	Existing clients of mental health Tx program for young people	Aboriginal and Torres Strait Islander, aged 13–24 years, attended ⩾2 sessions	N = 40	Mental health, well-being	NR	NR
Sun and Buys (2013a)	Pre–post with comparison	Queensland, Australia 2009–2011	Aboriginal CCHSs during health check consultations in ‘taster’ sessions	Aboriginal and Torres Strait Islanders, aged ⩾18 years, able to complete intervention and assessments Control: unable to attend intervention	1.6 N = 241 Tx group = 114, Ctrl group = 127	Resilience, stress, emotional well-being	241/291 = 83%	12-month FU: 56/114 = 49% Tx group; 54/127 = 42.5% Ctrl group
Sun and Buys (2013b)	Pre–post with comparison	Southeast Queensland, Australia Period NR	Aboriginal CCHSs during health check consultations	Aboriginal or Torres Strait Islander Australians, aged ⩾18 years, ⩾2 chronic diseases	N = 133 Tx group = 62, Ctrl group = 71	Stress, resilience, depression	NR	12-month FU: 45/62 = 73% Tx group; 27/71 = 38% Ctrl group
Tighe et al. (2017)	RCT	Broome, Derby, Fitzroy Crossing, Ringer’s Soak, Djarindjin, Lombadina, Mowanjum, Wangkatjungka, Kimberley region, Northwestern Australia 2013–2015	Men’s Outreach Service, Facebook, posters, flyers in medical centers and to health professionals, information sessions with health professionals	Indigenous Australians, aged ⩾18 years, PHQ-9 score ⩾10 or ⩾25 on K10, with or without suicide ideation in last 2 weeks	1.7N = 61 Tx group = 31, Waitlist group = 30	Depression, psychological distress	61/63 = 97%	29/31 = 93.5% Tx group; 30/30 = 100% waitlist group
Titov (2019)	Pre–post	Australia 2015–2016	Self-referral through website and website promoted via links from health websites and paid online ads	Aboriginal or Torres Strait Islander, aged ⩾18 years, registered with MindSpot from 1 January 2015–31 December 2016, born in Australia, eligible for publicly funded health services, not acutely suicidal or on psychotherapy	N = 70	Psychological distress, depression, generalized anxiety disorder/PTSD	70/780 = 9%	Post-Tx: 49/70 = 70% well-being course 21/70 = 30% Indigenous well-being course
Tosa et al. (2018)	Pre–post with comparison	New Mexico, United States 2012–2015	Tribal PI presenting study at two local high schools to parents of interested youth and in a local newsletter for youth in schools outside community	AI youth, grades 8–11, living within community borders, have parental consent	N = 55 Tx group = 30, Ctrl group = 25	Depression/sadness, stress (and coping), positive motivational states	NR	NR
Tsosie et al. (2011)	RCT	Seattle, Washington, United States 2009–2010	AI/AN recruiters approached hospital ward patients	AI/AN, aged ⩾18 years, with physical injury but not head, spinal, or self-inflicted; no active psychosis, mania or severe violence history	N = 30	PTSD symptoms, depression symptoms	30/36 = 83%	3- and 6-month FU: 25/30 = 83%
Tu et al. (2019)	Pre–post^b	Inner-city, Western Canada Period NR	Posters at clinic and reception staff introduced study to patients	Indigenous adult, clinic patient, no prior visits to the clinic-based Elders program, interest in program	N = 45	Depressive symptoms	NA	1-, 3- and 6-month FU: 41/45 = 91%
Varcoe et al. (2017)	Pre–post	Inner-city, Canada Period NR	Elder-led information circle at partner agency, word-of-mouth	Indigenous women, faced IPV, speak English, living in the study community	N = 21	Depression, trauma symptoms, mastery	NR	Post-intervention FU: 12/21 = 57%
Varcoe et al. (2021)	Pre–post	Suburban city and inner-city urban center, Western Canada Period NR	Local health and social service agencies, ads on community boards, presentations, word-of-mouth	Indigenous women, aged ⩾18 years, faced IPV, living in area adjacent to study site	N = 152	Depressive symptoms, Trauma symptoms, mastery	NR	Post-Tx FU: 88/152 = 58% 6-month FU: 79/152 = 52%

AI: American Indian; AN: Alaska Native; CCHSs: community controlled health services; Ctrl: control; DSM: Diagnostic and Statistical Manual of Mental Disorders; FU: follow-up; HTUG: historical trauma and unresolved grief intervention; IPV: intimate partner violence; IPT: interpersonal group psychotherapy; NA: not applicable; NR: not reported; PHQ: Patient Health Questionnaire; PI: principal investigator; PTSD: posttraumatic stress disorder; RCT: randomized controlled trial; Tx: treatment.

This observational study included Indigenous and non-Indigenous participants. We only described study characteristics as they related to the Indigenous participants reflecting a pre–post study design, measuring outcomes before and after the intervention for the same group of participants.

The authors described this study as having a prospective cohort design. For our review, we described this study as having a pre–post study design, as outcomes were measured before and after the intervention for the same group of participants.

Table 1 also includes the types of study participants and recruitment strategies. Some studies exclusively included women, patients enrolled in or frequenting health institutions, high school students and community event attendees. Recruitment strategies included flyers or posters, social media, websites and online ads and in-person approaches such as through community events, service providers or spaces, and door-to-door or word-of-mouth. One study did not recruit participants and instead used patient data from a clinical database (Bowen et al., 2020).

Description of studies

Supplemental Tables S3 and S4 describe the studies according to the TIDieR checklist and guide (Hoffmann et al., 2014).

Randomized controlled trials

The eight RCTs varied in treatment approaches. Brave Heart et al. (2020) incorporated psychoeducation on trauma and grief, and cultural healing practices with interpersonal group therapy. Tsosie et al. (2011) used individually tailored collaborative care management. Hatcher et al.’s (2016) intervention was based on problem-solving therapy. Another intervention used brief motivational care planning with principles of problem-solving therapy, motivational therapy and self-management (Nagel et al., 2009). Pearson et al. (2019) used trauma-informed cognitive processing therapy, and Korn et al. (2009) used polarity therapy. Tighe et al.’s (2017) trial delivered educational modules based on acceptance-based therapies delivered through an app (Shand et al., 2013). Gray et al. (2010) used cognitive-behavioral skills building with a culturally focused wellness intervention.

Pre–post studies

Ten single-group pre–post studies included diverse therapeutic approaches. Beckstead et al. (2015) incorporated dialectical behavior therapy with cultural complements. Two were based on cognitive behavioral therapy (CBT); Bennett et al. (2014) adapted CBT to Māori values and another used a culturally adapted ultra-brief CBT intervention with problem solving (Mathieson et al., 2012). Sabbioni et al. (2018) used a mental health service model incorporating culturally appropriate strategies and care. One study included online assessments and treatment courses on well-being and CBT (Titov et al., 2017, 2019). Varcoe et al. (2017, 2021) used teaching circles with Elders and cultural activities. Drumming was at the core of Dickerson et al.’s (2014) intervention for healing and community cohesion. Tu et al. (2019) partnered with Elders as part of routine primary care. Bowen et al. (2020) studied the integration of collaborative care management in primary care. Among three pre–post studies with comparison groups, Tosa et al. (2018) used extreme sports as place-based teachings aligned with the sacred water cycle, and Sun and Buys (2013a, 2013b) used a community singing program with culturally relevant songs.

Quality assessments

Quality was appraised using the EPHPP Quality Assessment Tool (Table 2). A total of 8 studies had a moderate global rating and 13 a weak global rating. For selection bias, 12 were rated weak as participants were unlikely to be representative of the target population or had a response rates less than 60%. Nine studies were moderate as participants were somewhat likely to be representative of the target population and had a 60–79% response rate, or were representative of the target population with no information on response rates. In total, 8 RCTs received strong ratings for study design and 13 pre–post studies were rated moderate. Ten studies were given a ‘N/A’ for confounders as they were single-group pre–post studies, two were weak for controlling for less than 60% of confounders and eight were strong for controlling all confounders in either the design (e.g. RCT) or analysis. All studies were rated strong for data collection as they employed validated and reliable measures. Three studies were rated strong for withdrawals and dropouts, with follow-up rates 80% or higher and describing reasons for withdrawals and dropouts. Six were rated moderate, meaning a 60–79% follow-up rate or non-applicability due to study design, and the remaining 12 were weak as they provided no reasons for their withdrawals and dropouts or because follow-up rates were less than 60%.

Table 2.

Quality of included studies.

Author	Selection bias	Study design	Confounders	Blinding	Data collection method	Withdrawals and dropouts	Global rating
Beckstead et al. (2015)	Moderate	Moderate	N/A	Weak	Strong	Moderate	Moderate
Bennett et al. (2014)	Moderate	Moderate	N/A	Weak	Strong	Moderate	Moderate
Bowen et al. (2020)	Moderate	Moderate	N/A	Weak	Strong	Weak	Weak
Brave Heart et al. (2020)	Moderate	Strong	Strong	Weak	Strong	Moderate	Moderate
Dickerson et al. (2014)	Weak	Moderate	N/A	Weak	Strong	Weak	Weak
Hatcher et al. (2016)	Weak	Strong	Strong	Moderate	Strong	Moderate	Moderate
Gray et al. (2010)	Weak	Strong	Strong	Strong	Strong	Moderate	Moderate
Korn et al. (2009)	Weak	Strong	Strong	Moderate	Strong	Strong	Moderate
Mathieson et al. (2012)	Moderate	Moderate	N/A	Weak	Strong	Weak	Weak
Nagel et al. (2009)	Moderate	Strong	Strong	Weak	Strong	Moderate	Moderate
Pearson et al. (2019)	Weak	Strong	Strong	Weak	Strong	Weak	Weak
Sabbioni et al. (2018)	Moderate	Moderate	N/A	Weak	Strong	Weak	Weak
Sun and Buys (2013a)	Weak	Moderate	Weak	Weak	Strong	Weak	Weak
Sun and Buys (2013b)	Weak	Moderate	Strong	Weak	Strong	Weak	Weak
Tighe et al. (2017)	Weak	Strong	Strong	Weak	Strong	Strong	Weak
Titov et al. (2019)	Weak	Moderate	N/A	Weak	Strong	Weak	Weak
Tosa et al. (2018)	Weak	Moderate	Weak	Weak	Strong	Weak	Weak
Tsosie et al. (2011)	Moderate	Strong	Strong	Moderate	Strong	Weak	Moderate
Tu et al. (2019)	Moderate	Moderate	N/A	Weak	Strong	Strong	Moderate
Varcoe et al. (2017)	Weak	Moderate	N/A	Weak	Strong	Weak	Weak
Varcoe et al. (2021)	Weak	Moderate	N/A	Weak	Strong	Weak	Weak

Indigenous individuals or groups with decision-making responsibilities at the study design level

Indigenous individuals or groups with decision-making responsibilities were described at the study design level (Supplemental Table S5). Decision-making at the design level occurred in Indigenous health settings and by Indigenous service providers (Beckstead et al., 2015; Bennett, 2009; Bennett et al., 2014; Dickerson et al., 2014; Korn et al., 2009; Mathieson et al., 2012; Nagel et al., 2009; Pearson et al., 2019; Sabbioni et al., 2018; Sun and Buys, 2013a, 2013b; Tighe et al., 2017; Titov et al., 2019; Tu et al., 2019), cultural leaders (e.g. Elders, Medicine Man, spiritual counselor) (Beckstead et al., 2015; Bennett, 2009; Bennett et al., 2014; Sabbioni et al., 2018; Sun and Buys, 2013a, 2013b; Tsosie et al., 2011; Tu et al., 2019; Varcoe et al., 2017, 2021), Indigenous community members (Dickerson et al., 2014; Gray et al., 2010; Mathieson et al., 2012; Nagel et al., 2009; Pearson et al., 2019; Tighe et al., 2017; Titov et al., 2019; Tosa et al., 2018) and research team members (Dickerson et al., 2014; Mathieson et al., 2012; Nagel et al., 2009; Titov et al., 2019; Tosa et al., 2018; Varcoe et al., 2017, 2021). Decision-making also involved Indigenous research ethics boards (Beckstead et al., 2015; Brave Heart et al., 2020; Pearson et al., 2019; Tighe et al., 2017; Tu et al., 2019) and other groups (e.g. governing or tribal bodies; advisory, consultation, steering, and reference groups, committees, or boards) (Beckstead et al., 2015; Bennett, 2009; Bennett et al., 2014; Brave Heart et al., 2020; Dickerson et al., 2014; Gray et al., 2010; Hatcher et al., 2011, 2016; Mathieson et al., 2012; Pearson et al., 2019; Titov et al., 2019; Tu et al., 2019; Varcoe et al., 2017, 2021). Decision-making by Indigenous individuals or groups was not reported in one study (Bowen et al., 2020).

Involvement in the study design included adapting or determining the intervention content in all but seven studies (Bowen et al., 2020; Hatcher et al., 2011, 2016; Korn et al., 2009; Sabbioni et al., 2018; Sun and Buys, 2013a, 2013b; Tu et al., 2019), approving, endorsing or informing the study proposal or protocol (Bennett, 2009; Bennett et al., 2014; Brave Heart et al., 2020; Dickerson et al., 2014; Gray et al., 2010; Mathieson et al., 2012; Pearson et al., 2019; Sabbioni et al., 2018; Sun and Buys, 2013a, 2013b; Tosa et al., 2018; Tu et al., 2019; Varcoe et al., 2017, 2021), and implementing or overseeing implementation of the intervention (Gray et al., 2010; Sun and Buys, 2013a, 2013b; Varcoe et al., 2017, 2021).

Specificity and diversity of Indigenous population and Indigenous-specific content in the intervention and research process

The specificity of the studies to Indigenous populations is described in Supplemental Table S6. All studies were specific to Indigenous populations, but only two studies considered the populations’ diversity by engaging specific communities (Nagel et al., 2009; Tighe et al., 2017). Indigenous-specific content (e.g. ceremonies, oral and musical traditions, and weaving and crafting) was described in all but two studies (Bowen et al., 2020; Sun and Buys, 2013b). Nine studies explicitly included Indigenous worldviews or values into the intervention (Bennett et al., 2014; Brave Heart et al., 2020; Hatcher et al., 2011, 2016; Mathieson et al., 2012; Nagel et al., 2009; Pearson et al., 2019; Sabbioni et al., 2018; Varcoe et al., 2017, 2021). Five studies used Indigenous-specific measures or measures validated for use in Indigenous peoples (Brave Heart et al., 2020; Dickerson et al., 2014; Hatcher et al., 2011, 2016; Pearson et al., 2019; Sun and Buys, 2013b) (Supplemental Table S6).

Indigenous peoples’ involvement in conducting research activities and implementing the intervention

We identified five potential study stages for Indigenous involvement (Supplemental Table S7). Indigenous people set the study aims in four studies (Bennett et al., 2014; Hatcher et al., 2016; Tosa et al., 2018; Tu et al., 2019). Six studies had Indigenous involvement in recruitment (Gray et al., 2010; Korn et al., 2009; Tighe et al., 2017; Tosa et al., 2018; Tsosie et al., 2011; Varcoe et al., 2017). Indigenous health service providers and personnel (Gray et al., 2010; Korn et al., 2009; Tighe et al., 2017), research team and administrative personnel (Tosa et al., 2018; Tsosie et al., 2011), and cultural leaders (Korn et al., 2009; Varcoe et al., 2017) were involved in recruitment. In five studies, recruitment took place in Indigenous settings (e.g. clinics, service centers, pow wows, tribal health programs, health fairs) (Korn et al., 2009; Pearson et al., 2019; Sun and Buys, 2013a, 2013b; Tu et al., 2019). Only eight studies involved Indigenous peoples in the data collection (Mathieson et al., 2012; Sabbioni et al., 2018; Tighe et al., 2017; Tosa et al., 2018; Tsosie et al., 2011), analysis (Tosa et al., 2018; Tu et al., 2019) or sharing (Dickerson et al., 2014; Tosa et al., 2018; Tu et al., 2019) stages. Fifteen studies had Indigenous service providers delivering the intervention (Beckstead et al., 2015; Brave Heart et al., 2020; Dickerson et al., 2014; Gray et al., 2010; Hatcher et al., 2016; Nagel et al., 2009; Sabbioni et al., 2018; Sun and Buys, 2013a, 2013b; Tighe et al., 2017; Tosa et al., 2018; Tu et al., 2019; Varcoe et al., 2017, 2021) and Indigenous staff coordinating and administering the intervention (Hatcher et al., 2016; Sun and Buys, 2013a, 2013b; Tsosie et al., 2011). Six studies included research training opportunities exclusively for Indigenous persons on facilitating the intervention (Beckstead et al., 2015; Brave Heart et al., 2020; Gray et al., 2010; Tosa et al., 2018), data collection and analysis (Tosa et al., 2018) and on trauma (Varcoe et al., 2017, 2021).

Synthesis of mental health outcomes

The mental health outcomes measured included mood and anxiety disorders, PTSD and trauma symptoms, and general mental health measures (Table 3).

Table 3.

Summary of findings.

Author	Outcome and measure	Analysis	Intervention group finding	Control group finding	Unadjusted measure of association	Adjusted measure of association
Beckstead et al. (2015)	Psychological distress, Youth Outcome Questionnaire Self-Report Edition	Pre/post mean (SD), p value, Cohen’s d	Pre: 50.78 (32.14), Post: 12.04 (26.50), p < 0.0001, 1.315 (large)	NA	NA	NA
		n (%) of clinical range sample meeting criteria for clinically significant change at termination	Deteriorated: 0 (0.0)No change: 10 (9.8)Reliable change: 2 (2.0)Clinically significant change: 90 (88.2)	NA	NA	NA
		n (%) of below clinical range sample meeting criteria for clinically significant change at termination	Deteriorated: 0 (0.0)No change: 0 (0.0)Reliable change: 109 (100)Clinically significant change: 0 (0.0)	NA	NA	NA
Bennett et al. (2014)	Depression, BDI-II	Pre/post/6-mo mean (SD), p value	Pre: 28.69 (11.15)Post: 10.71 (13.86), p < 0.016-mo. post: 10.93 (14.81),p < 0.01	NA	NA	NA
Bowen et al. (2020)	Depression, PHQ-9	Baseline/Last PHQ-9 scores, mean (SD)	Pre: 13.9 (6.2)Post: 10.0 (6.6)	NA	NA	NA
Brave Heart et al. (2020)	Depression, Hamilton Depression Scale-24	Baseline/4-, 8-, 12-week (end of Tx), 20-week (follow-up)mean (SD)	Baseline: 30.2 (8.1)4-week: 21.0 (8.2)8-week: 23.2 (8.9)12-week: 18.1 (11.9)20-week: 19.9 (8.8)	Baseline: 30.2 (6.4)4-week: 22.6 (13.5)8-week: 18.5 (12.4)12-week: 14.1 (12.1)20-week: 16.7 (12.1)	NR	NR
		Within condition, slope for time [95% CI]	−2.60 [−3.75, −1.45]	−3.07 [−4.44, −1.69]	NR	NR
	Depression,PHQ-9	NR	NR	NR	NR	NR
	Depression, CESD	Administered before intervention as part of IPS	NR	NR	NR	NR
	PTSD, PCL-C	Baseline/12 (end of Tx), 20-week (follow-up), mean (SD)	Baseline: 49.2 (18.0)12-week: 51.7 (13.9)20-week: 51.9 (16.4)	Baseline: 50.3 (17.4)12-week: 41.1 (19.7)20-week: 39.8 (18.0)	NR	NR
		Within condition slope for time [95% CI]	0.09 [−1.39, 1.57]	−2.29 [−4.03, −0.56]	NR	NR
Dickerson et al. (2014)	Psychiatric symptoms, Brief Symptom Inventory	Baseline/6-, 12-weekmean (SD N/R)	Baseline: 31.86-week: 14.212-week: 20.4	NA	NA	NA
	Psychiatric status, Addiction Severity Index, Native American Version	Baseline/6-, 12-weekmean (SD N/R), (n)	Baseline: 0.18 (n = 8)6-week: 0.10, p < 0.05 (n = 8)12-week: 0.09 (n = 5)	NA	NA	NA
Gray et al. (2010)	Depression, BDI	Slope [95% CI] of regression line from baseline to 6 months, p value	1.11 b = 0.42 [0.25, 0.58]p < 0.001	1.13 b = 0.29 [0.14, 0.43]p < 0.001	NA	NA
	Self-esteem,Rosenberg Self-Esteem Scale	Slope [95% CI] of regression line from baseline to 6 months, p value	b = 0.60 [0.45, 0.74]p < 0.001	b = 0.52 [0.36, 0.68]p < 0.001	NA	NA
Hatcher et al. (2016)	Anxiety*, HADS	Baseline score, mean (SD)*Measured also at 3 months, 1 year but not reported	13.4 (4.5)	12.0 (N/R)	NR	NR
	Depression*, HADS	Baseline score, mean (SD)*Measured at 3 months, 1 year but not reported	9.7 (4.0)	8.7 (4.1)	N/R	NR
	Hopelessness, Beck Hopelessness Scale	3 months, 1 year mean (SD), % score < 9	3 months: 6.6 (5.8), 66.1%1 year: 5.0 (4.4), 80.3%	3 months: 7.4 (5.8), 64.6%1 year: 5.7 (4.8), 74.4%	NR	NA
		Baseline to 3-month and 1-year change mean (SD); Estimate of the difference, SE, 95% CI, p value	3 months: −4.5 (5.6)1 year: −6.6 (6.0)	3 months: −1.3 (7.1)1 year: −2.8 (5)	3 months: −1.7 (0.5), [−3.4, −0.01] p = 0.05;1 year: −1.6 (1.0), [−3.4, 0.3], p = 0.11	NR
	Sense of belonging*, Sense of Belonging Instrument-P	Baseline score, mean (SD)*Measured also at 3 months, 1 year but not reported	47.6 (11.7)	45.7 (11.9)	NA	NA
Korn et al. (2009)	Depression, CESD	Mean (SD) change from baseline, p value; β (SE) for treatment effect, p value	−7.9 (8.25)p = 0.045	−1.9 (9.5)	−6.0 (2.9),p = 0.045	−6.4 (2.5),p = 0.015
	Stress, Perceived Stress Scale	Mean (SD) change from baseline, p value;β (SE) for treatment effect, p value	−8.3 (7.54)p = 0.01	−2.5 (6.2)	−5.8 (2.3),p = 0.014	−5.7 (1.9),p = 0.006
	Mental health, SF-36	Mean (SD) change from baseline, p value	14.2 (15.4)p = 0.27	6.7 (25.2)	NR	NR
	Mental component summary, SF-36	Mean (SD) change from baseline, p value	4.9 (7.9)p = 0.76	4.0 (9.1)	NR	NR
Mathieson et al. (2012)	Psychological distress, K10	Mean [95% CI] improvement 2-, 6-, 12-week post-intervention	2-week: 5.2 [1.5, 8.8], p = 0.0096-week: 5.1 [0.9, 9.3], p = 0.02012-week: 4.2 [−0.5, 8.96], p = 0.077	NA	NA	NA
Nagel et al. (2009)	Psychological distress, K10	NR	NR	NR	NR	NR
	Severity of mental illness, HoNOS	Change in mean health at 6, 12, 18 months, p value	6 months: 18.09, p = 0.06812 months: N/R18 months: N/R	6 months: 20.6812 months: 16.1518 months: 16.72	NA	NR
Pearson et al. (2019)	PTSD, PTSD Symptom Scale Self-Report Version	Pre/immediate post/3-month post-intervention mean (SD), intervention effect d, p value	Pre: 27.1 (10.8)Post: 14.7 (8.4)3-month post: 19.0 (9.7)d = 1.03, p < 0.001	Pre: 30.1 (11.7)Post: 22.5 (14.4)3-month post: 20.0 (13.0)	NR	NR
		Reduction in symptoms associated with additional sessions, Estimate [95% CI]	NA	NA	−1.32 [−1.93, −0.70]	NA
Sabbioni et al. (2018)	Mental health, HoNOS	Pre/post-intervention mean (SD), range	Pre: 17.3 (6.4), 4–29Post: 14.4 (6.7), 0–25	NA	NA	NA
	Well-being, Outcome rating scale	Pre/post-intervention mean (SD), range	Pre: 19.7 (9.1), 3.6–40.0Post: 27.0 (10.5), 1.1–40.0	NA	NA	NA
		Within-group difference between first and last ORS session score, paired t test, effect size	t[39]= 4.0, p < 0.001;0.69	NA	NA	NA
		ORS changes	65% improved (35% achieved clinical recovery, 30% clinical cut-off) 25% no change, 10% deteriorated	NA	NA	NA
Sun and Buys (2013a)	Stress, Stressful life events	Post-interventionn (%), difference between intervention and control groups, chi-square test	No stress: 14 (25.0)1 event: 14 (25.0)2 events: 9 (16.1)3 events: 19 (33.9)	No stress: 9 (16.6)1 event: 24 (44.4)2 events: 9 (16.6)3 events: 22 (4.7)	5.56, p < 0.05	NA
	Resilience, Questionnaire (6 resilience dimensions)	Pre/post-intervention,F [Group × time interaction]	Pre: 3.25 (1.49)Post: 3.77 (1.78)	Pre: 3.48 (1.43)Post: 3.65 (1.47)	0.82	NA
	Emotional well-being, Singing Activity Participation Questionnaire	Pre/post-intervention,F [Group × time interaction]	Pre: 22.49 (18.61)Post: 38.28 (5.42)	Pre: 6.89 (13.58)Post: 2.10 (0.39)	25.40(p < 0.001)
Sun and Buys (2013b)	Stress, Stressful life events questions	Mean score at baseline (SD), mean change from baseline to 12 months (SE), within-group pre/post change p value, mean change between singing and control post-intervention p value	2.45 (2.64), 0.48 (0.47), within group p = 0.32Mean change p = 0.11	2.97 (2.16), −0.31 (0.74), within group p = 0.67	NA	NA
	Depression, N/R	Mean score at baseline (SD), mean change from baseline to 12 months (SE), within-group pre/post change p value, mean change between singing and control post-intervention p value	5.19 (3.09), 0.85 (0.57), Within group p = 0.14Mean change p = 0.23	5.40 (3.27), 0.11 (0.98), Within group p = 0.91	NA	NA
	Resilience, N/R	Mean score at baseline (SD), mean change from baseline to 12 months (SE), within-group pre/post change p value, mean change between singing and control post-intervention p value	3.28 (1.52), −0.20 (0.27), Within group p = 0.47Mean change p = 0.42	2.97 (2.16), −0.84 (0.43),Within group p = 0.56	NA	NA
Tighe et al. (2017)	Depression, PHQ-9	Post-intervention mean (SD), p value	8.9 (5.4), p ⩽ 0.05	12.8 (5.5)	NA	NA
	Distress, K10	Post-intervention mean (SD), p value	22.7 (7.4), p ⩽ 0.01	27.9 (8.0)	NA	NA
Titov et al. (2019)	Psychological distress, K10	Pre/post treatment mean (SD), effect sizes	Pre: 31.6 (7.2)Post: 20.7 (6.7),1.57 (1.18–1.94)	NA	NA	NA
		Pre/post mean (SD), effect sizes for Indigenous well-being course Cohen’s d	Pre: 32.3 (9.0)Post: 21.1 (7.6),1.34 (0.65–1.99)	NA	NA	NA
	Depression symptoms, PHQ-9	Pre/post mean (SD), effect sizes	Pre: 15.2 (6.2)Post: 6.8 (4.0),1.60 (1.21, 1.97)	NA	NA	NA
		Pre/post mean (SD), effect sizes for Indigenous wellbeing course Cohen’s d	Pre: 15.0 (7.3)Post: 6.9 (5.5),1.25 (0.57, 1.89)	NA	NA	NA
	Anxiety symptoms,Generalized anxiety disorder scale 7	Pre/post mean (SD), effect size	Pre: 12.8 (4.8)Post: 6.2 (3.4),1.57 (1.18–1.94)	NA	NA	NA
		Pre/post mean (SD), effect sizes for Indigenous well-being course Cohen’s d	Pre: 13.0 (5.1)Post: 6.6 (4.6),1.32 (0.63–1.96)	NA	NA	NA
Tosa et al. (2018)	Depression, New Mexico Youth Risk and Resiliency Surveillance Survey	Maximum exposure group mean (SD)Minimum exposure group mean (SD)	Max: 0.00 (0.00),Min: 0.18 (0.39), Max. significantly different from control and not min.	No exposure0.44 (0.51)	NA	NA
		Effect for program exposure on depression at p < 0.05 for three group conditions	F(2, 52) = 5.44, p = 0.007	NA	NA	NA
	Stress and coping, Brief Coping Scale	Maximum exposure group mean (SD)Minimum exposure group mean (SD)	Max: 2.54 (0.89),Min: 2.69 (0.95), Max. significantly different from control and not min.	No exposure3.5 (1.2)	NA	NA
	Positive motivational states, Hope Scale	Mean (SD), Cronbach’s alpha, paired-sample t-test	Pre: 44.69 (6.28), α= 0.31Post: 49.23 (7.18), α= 0.65t = 3.65, p = 0.003	NA	NA	NA
Tsosie et al. (2011)	PTSD, PCL-C	3-, 6-month post-intervention mean (SD)	3 months: 39.8 (16.6)6 months: 35.5 (15.7)	3 months: 35.2 (12.2)6 months: 32.5 (12.2)	NA	NA
	Depression, PHQ-9	3-, 6-month post-intervention mean (SD)	3 months: 12.2 (7.4)6 months: 8.4 (7.2)	3 months: 11.3 (6.2)6 months: 9.0 (6.6)	NA	NA
Tu et al. (2019)	Depression, PHQ-9	1-, 3-, 6-month post-intervention mean, mean change from baseline, p value in those score ⩾10	1 month: 10.8, −4.9, p = 0.0023 months: 9.6, −6.2, p < 0.0016 months: 10.8, −4.5, p = 0.001	NA	NA	NA
Varcoe et al. (2017)	Depression, CESD-R	Pre/post-intervention mean (SD)	Pre: 28.8 (13.6)Post: 23.4 (16.9)	NA	NA	NA
	Trauma, PCL-C	Pre/post-intervention mean (SD)	Pre: 50.6 (11.0)Post: 41.4 (15.1)	NA	NA	NA
	Mastery, PMS	Pre/post-intervention mean (SD)	Pre: 24.3 (6.0)Post: 25.0 (6.0)	NA	NA	NA
Varcoe et al. (2021)	Depression, CESD-R	Pre/post/6-month post-intervention mean	Pre: 28.25Post: 22.856 months: 23.94	NA	NA	NA
		Effect size, p value	Pre/post: −0.34, p < 0.001Pre/6 months: −0.28, p = 0.001	NA	NA	NA
	Trauma symptoms, PCL-C	Pre/Post/6-month post-intervention mean	Pre: 49.05Post: 43.866 months: 42.49	NA	NA	NA
		Effect size, p value	Pre/post: −0.32, p = 0.001Pre/6 months: −0.40, p < 0.001	NA	NA	NA
	Mastery, PMS	Pre/post/6-month post-intervention mean (SD)	Pre: 23.56Post: 25.036 months: 25.72	NA	NA	NA
		Effect size, p value	Pre/post: 0.27, p = 0.011Pre/6 month: 0.40, p < 0.001	NA	NA	NA

BDI: Beck Depression Inventory; CESD: Center for Epidemiological Studies Depression scale, R: Revised; CI: confidence interval; IPS: Indigenous Peoples Survey; HADS: Hospital Anxiety and Depression Scale; HoNOS: Health of the Nation Outcome Scale; K10: Kessler psychological distress scale 10; NA: not applicable; NR: not reported; ORS: outcome rating scale; PCL-C: PTSD Checklist for civilians; PHQ-9: Patient Health Questionnaire-9; PMS: Pearlin Mastery Scale; PTSD: posttraumatic stress disorder; SD: standard deviation; SE: standard error; SF-36: 36-Item short form survey.

Mood and anxiety disorders

Among six RCTs evaluating depressive symptoms, two measured statistically significant reduced symptoms immediately post-intervention (Korn et al., 2009; Tighe et al., 2017) and one at 6 months after baseline in both arms (Gray et al., 2010). One trial measured statistically significant lower depression scores at 20 weeks after baseline (Brave Heart et al., 2020). Depression scores were not reduced in one RCT (Tsosie et al., 2011) and one trial did not report their scores (Hatcher et al., 2016). Among six single-group pre–post studies assessing depression, three studies showed statistically significant reductions in depression immediately post-intervention and at 6-month follow-up (Bennett et al., 2014; Tu et al., 2019; Varcoe et al., 2021) as well as at 1- and 3-month post-intervention (Tu et al., 2019). In the three remaining pre–post studies, depression was reduced immediately post-intervention, but statistical significance was not provided (Bowen et al., 2020; Titov et al., 2019; Varcoe et al., 2017). One pre–post study with comparison group showed statistically significant lower depression scores immediately post-intervention (Tosa et al., 2018), but the other study did not (Sun and Buys, 2013b).

Anxiety was measured in an RCT and a pre–post study. In the RCT, anxiety scores were not reported (Hatcher et al., 2016). The pre–post study measured a statistically significant decrease in scores immediately post-intervention using a measure for anxiety, panic and PTSD (Titov et al., 2019).

Psychological distress was assessed in two RCTs and three pre–post studies. One RCT had a statistically significant lower mean distress score post-intervention (Tighe et al., 2017), and the second RCT did not report their results (Nagel et al., 2009). In two pre–post studies, lower mean distress scores were statistically significant immediately post-intervention (Beckstead et al., 2015) and at 2- and 6-week post-intervention (Mathieson et al., 2012). In the third study, distress was lower immediately post-intervention, but statistical significance was not calculated (Titov et al., 2019).

PTSD or trauma symptoms

Three RCTs examined PTSD symptoms. One trial had a statistically significant reduction in mean PTSD symptom scores immediately and 3 months post-intervention (Pearson et al., 2019), and in the intervention arm for two RCTs, symptoms were not reduced (Brave Heart et al., 2020; Tsosie et al., 2011). Among three pre–post studies, one study had a statistically significant reduction in PTSD (Titov et al., 2019), and a second study showed decreased trauma symptoms at post-intervention, but statistical significance was not calculated (Varcoe et al., 2017). In a third study, trauma symptoms were statistically significantly lower immediately post-intervention and at 6 months (Varcoe et al., 2021).

General mental health measures

In one RCT, mental health score changes were not statistically significant (Korn et al., 2009). A pre–post study found reduced mental health scores immediately post-intervention, but statistical significance was not calculated (Sabbioni et al., 2018).

A measure of well-being showed statistically significant improvements immediately post-intervention in one pre–post study (Sabbioni et al., 2018). Social and emotional well-being measured in two pre–post studies with comparison groups using the same intervention (Sun and Buys, 2013a, 2013b) showed statistically significant improvement in well-being in only one of the studies (Sun and Buys, 2013a).

One RCT measured a statistically significant reduction in perceived stress scores in the intervention arm (Korn et al., 2009). Among three pre–post studies with comparison groups, two studies using the same intervention measured fewer stressful events in the intervention group (Sun and Buys, 2013a, 2013b), but statistical significance was only measured in one of the studies (Sun and Buys, 2013a). In the third study, stress and coping scores were statistically significantly improved in the intervention group (Tosa et al., 2018).

Psychiatric symptoms and status were assessed in one pre–post study and statistically significant reduction in status only was observed at 6 and 12 weeks (Dickerson et al., 2014).

Other strength-based mental health outcomes

One RCT saw a statistically significant reduction in hopelessness in the intervention at 3-month follow-up, and although it measured sense of belonging only, the baseline measure was reported (Hatcher et al., 2016). Another RCT demonstrated statistically significant improvements in self-esteem at 14-week follow-up in both arms (Gray et al., 2010). Two pre–post studies of the same intervention observed increased mastery (Varcoe et al., 2017, 2021), but statistically significant improvements immediately post-intervention and at 6-month follow-up were only measured in one study (Varcoe et al., 2021). Two pre–post studies of the same intervention with comparison groups measured resilience and did not show statistically significant changes in the intervention group (Sun and Buys, 2013a, 2013b). Another pre–post study with comparison showed a statistically significant improvement in positive motivational state immediately post-intervention (Tosa et al., 2018).

Discussion

Summary of results

This is one of the largest systematic reviews to date on mental health interventions for Indigenous populations. It demonstrates that interventions are mostly effective in improving mental health outcomes in the short term, but the extent to which they engage communities in the research and intervention can vary widely. Meta-analysis could not be conducted due to the heterogeneity of the study designs. Depression was the most frequently examined outcome and 8 of 14 studies observed statistically significant improvements. Three of the six studies that assessed PTSD symptoms showed statistically significant improvements. Three of five studies examining psychological distress and two of four studies on the impact on stress showed statistically significant improvements. Only two studies looked at anxiety and one showed a statistically significant decrease. Six of the fourteen other studies all examining various general mental health or related outcomes (e.g. resilience, mastery) reported statistically significant positive results associated with the interventions.

Comparisons to other systematic reviews

Four similar systematic reviews have been published between 2015 and 2018 (Antonio and Chung-Do, 2015; Leske et al., 2016; Pollok et al., 2018; Pomerville et al., 2016) with the latest article being from 2015. Articles in our review were published between 2009 and 2020 and 11 of 21 between 2016 and 2020. Among the four reviews, four unique articles overlapped (Beckstead et al., 2015; Dickerson et al., 2014; Mathieson et al., 2012; Nagel et al., 2009).

Pollok et al. (2018) evaluated experimental studies of behavioral and pharmacological interventions for depression in any setting, whereas Leske et al. (2016) examined pharmacological, psychological and educational interventions for both mental and substance use disorders in Australia, Canada, New Zealand and the United States. Pomerville et al. (2016) aimed to understand the landscape of empirical work on psychotherapies for Indigenous populations in Australia, Canada, New Zealand and the United States, specifically understanding how much research exists, the types of research and their key findings. Antonio and Chung-Do (2015) examined mental health and substance use disorder interventions for Indigenous adolescents and assessed the degree to which an intervention was culturally tailored. Articles in these reviews were ineligible for our review as they were pharmacological interventions or had qualitative designs, irrelevant outcomes (e.g. tobacco and alcohol dependence) or no/lower age requirements. Our review builds on these efforts and few existing reviews have completed such a systematic, extensive examination of Indigenous involvement or content of interventions.

Indigenous involvement in interventions and research

Assessment and reporting of Indigenous involvement and content, whether in the context of original research or reviews, is important for many reasons. As observed in this review, studies varied greatly in this regard and perhaps most apparently so, in the reporting. Not only were actual involvement of Indigenous peoples and organizations and their roles often unclear, wording to describe involvement also varied greatly. Thus, conducting such assessments and reporting the results in original research can encourage accountability throughout the research process and transparency for readers. Researchers can consider using tools such as the CONSolIDated critERtia for strengthening the reporting of health research involving Indigenous Peoples (CONSIDER) statement to strengthen their reporting of health research involving Indigenous Peoples (Huria et al., 2019) or the Aboriginal and Torres Strait Islander Quality Appraisal Tool, a research assessment tool from Indigenous perspectives (Harfield et al., 2020).

Of course, these are only aides for researchers to critically reflect on the purpose and implications of their research beyond the ‘outcomes of interest’. Also, assessing Indigenous involvement can speak to the quality of the intervention and study, their effectiveness and feasibility (e.g. improved health outcomes, study participant recruitment, community engagement, uptake of research activities, self-determination, data sovereignty). In terms of quality, all the studies had either a weak (n = 12) or moderate (n = 9) global rating. Increased engagement of Indigenous people throughout the research process may have improved several quality assessment domains such as selection bias (i.e. response rate and recruitment) and withdrawals/dropouts. Our findings showed limited Indigenous involvement in recruitment which could have impacted the sample size to detect clinically or statistically significant outcomes (Faber and Fonseca, 2014). Also, perhaps greater involvement would have led to the collection of more information on reasons for dropouts and withdrawals important factors in determining the rating of this domain. Understanding the motivation of Indigenous people to participate in research has been shown to differ from non-Indigenous people and can largely be met by engaging Indigenous people. For example, the motivations for Indigenous people to participate in research included benefits to the community, the expression of specific values (e.g. reciprocity, respect, honesty) in the research process, as well as the selection of meaningful outcomes and research interests (Guillemin et al., 2016; Nadalin et al., 2010). Finally, Indigenous involvement in capacity building activities such as conducting the research and implementing interventions may sustain positive mental health outcomes beyond the duration of the research. Trained Indigenous persons living in the community may integrate intervention activities and skills acquired into programming or services. CONSIDER and the Aboriginal and Torres Strait Islander quality appraisal tool speak to outcomes that are beneficial at a community level versus solely individual level measures (Harfield et al., 2020; Huria et al., 2019). They also consider the use of Indigenous methodologies in contrast to western research principles (Harfield et al., 2020; Huria et al., 2019). We have developed an exploratory table (Supplemental Table S8) which should be reviewed cautiously given that future studies should conduct in-depth investigations into the level and duration of Indigenous involvement for example, as well as other yet to be identified factors that may be more meaningful to Indigenous peoples and communities. In fact, our supplementary Tables S5–S7 are important Indigenous-specific outcomes that only arise through Indigenous involvement that are as equally meaningful as improved mental health outcomes (Harding and Oetzel, 2019; Harfield et al., 2020; Huria et al., 2019).

With a(n) (ongoing) history of medicine and research being used as tools of continued colonial violence (Hawkes et al., 2017; Hyett et al., 2018; Smylie, 2005; Tuck, 2009), it is imperative that non-Indigenous researchers consider and address implications of their research given their positionality and answer whether the research should be conducted in the first place (Kwaymullina, 2016). Also whether institutionalized research ethics frameworks and practices of universities and colonial state governments agencies are truly aligned with reciprocity and respect within Indigenous epistemologies (Hawkes et al., 2017). In addition, it is important to consider whether these frameworks and practices are aligned with national and local Indigenous-defined research ethics for each country (Canadian Institutes of Health Research, Natural Sciences and Engineering Research Council of Canada and Social Sciences and Humanities Research Council, 2018; Hayward et al., 2021; National Health and Medical Research Council, 2018).

Limitations

There are several limitations in our review. First, mental health is also encompassed by and conceptualized through the term ‘social and emotional wellbeing (SEWB)’ in Australia. Aboriginal and Torres Strait Islander Peoples’ concept of SEWB emphasizes connections to family, kin, community, land, spirituality and health and is contextualized in the broader sociopolitical context in which these connections have been disrupted (Gee et al., 2014). As our search terms did not include ‘social and emotional wellbeing’, relevant studies from Australia may have been missed. However, it is important to note that we did include other terms such as ‘wholeness, wellness, wellbeing’ that may have been keywords or MeSH terms of articles of interest in our search strategy (Supplemental Table S1). Also, ‘mental health and mental disorder’, keywords in our search strategy, were keywords in articles on SEWB (Calma et al., 2017; Gee et al., 2014). As in the systematic reviews described above on similar topics, we have included Indigenous peoples from Canada, the United States, Australia and New Zealand. Therefore, our findings cannot be generalized across Indigenous populations in different countries and within the Indigenous populations of a country which is why we have ensured that our review specifies the Indigenous populations and their communities if reported (Supplemental Table S6).

Second, our assessment of Indigenous involvement and content was restricted to the information written in the articles. It is not yet commonplace to describe Indigenous relationships or involvement in research in journal articles. Authors make subjective decisions on what to include or exclude and are limited by academic journals’ publication requirements like word counts or editing processes. We did not conduct external searches to investigate the studies, unless the article in our review directed readers to another publication to increase information on the protocol. We noted whether there were Indigenous primary authors/investigators, but if this was not explicitly described in the articles (Brave Heart et al., 2020), they were not recorded.

One final limitation may be that our review lacks more ‘rigorous’ studies, as indicated by the lack of ‘strong’ quality studies. However, as discussed above, there are legitimate questions around whether existing, non-Indigenous assessment tools are appropriate as standalone tools for evaluating ‘quality’ of research involving Indigenous peoples. Furthermore, we recognize the challenges in implementing more resource-intensive and rigid RCT designs.

Implications and recommendations

The observations in our review support the establishment and uptake of reporting guidelines for Indigenous health research to improve both the implementation and description of research. It is particularly important to understand power relations, accountability and reciprocity in Indigenous health research in the context of colonial states, where medicine, public health and ‘knowledge production’ more generally have facilitated and reinforced colonial systems (Schnarch, 2004).

Through the cultural assessment, we learned that six interventions trained community members (Beckstead et al., 2015; Brave Heart et al., 2020; Gray et al., 2010; Tosa et al., 2018; Varcoe et al., 2017, 2021) (where applicable, given some were retrospective or observational), extending the impact of the intervention beyond the study period. Hiring and training community members can be beneficial since clinical skills are transferrable beyond the duration of the intervention and financial resources are directed to the community. Funding and resources are integral to supporting self-determination and cultural continuity in many Indigenous communities (Auger et al., 2016; First Nations Health Authority, 2018). Any positive impacts of interventions may be better sustained if researchers were committed to also providing a plan for what happens after the ‘completion’ of the intervention and research. To the best of our knowledge, most of the studies did not report a plan to follow-up with the community after the intervention, ways to disseminate findings, or plans to apply findings to future program or policy.

Cultural continuity, understood as intergenerational cultural connectedness, is a determinant of Indigenous health (Auger, 2016). Self-determination and governance are crucial in improving Indigenous health at the population level (Alfred, 2009; Auger et al., 2016; Chandler and Lalonde, 1998). Therefore, interventions and policy changes for improving Indigenous mental health should aim to promote cultural continuity, self-determination and self-governance. Most studies in this review addressed cultural continuity by facilitating the transmission of cultural knowledge or incorporating Indigenous values and healing practices as part of the intervention. Self-governance and self-determination were rarely the goal for these interventions, likely because mental health interventions tend to focus on treating or improving an individual’s symptoms. One study (Tosa et al., 2018) had participating youth lead a project to address an issue from their community as part of the intervention, which could potentially address self-determination to some degree.

Cultural continuity and self-determination also have micro- and macro-level dimensions (Auger, 2016; Auger et al., 2016) and therefore their operationalization may differ vastly. Interventions here do not address self-determination and self-governance in the macro-, structural sense. Here, we recognize the challenges in that public health ‘interventions’ are questionable instruments to address deeply embedded structural injustices. In turn, there are tensions in how public health is implicated in this context—as colonial governments continue to invest in public health research and interventions, they simultaneously continue to disregard and actively preserve root causes of health inequities.

Conclusion

A wide range of interventions identified in our review demonstrated mental health improvements. However, it is difficult to draw generalizable conclusions on intervention effectiveness, given study heterogeneity. Future studies should first consider the appropriateness of actually conducting their research and intervention. Then, researchers should thoroughly assess the Indigenous involvement and content of their interventions throughout the research process. Finally, it is important to consider the implications of the research, whether and how they address important social and structural determinants of mental health for Indigenous peoples.

Supplemental Material

sj-docx-1-anp-10.1177_00048674221089837 – Supplemental material for Systematic review of Indigenous involvement and content in mental health interventions and their effectiveness for Indigenous populations

Supplemental material, sj-docx-1-anp-10.1177_00048674221089837 for Systematic review of Indigenous involvement and content in mental health interventions and their effectiveness for Indigenous populations by Rachel Seungyun Lee, Hilary K Brown, Sarah Salih and Anita C Benoit in Australian & New Zealand Journal of Psychiatry

Footnotes

Acknowledgements

We would like to thank Vincci Lui, Librarian from the University of Toronto, for contributing to the development of our search strategy as well as Catherine Moses and Priya Prabhakar who contributed to developing the search strategy and for screening titles and abstracts. Nadine Eltayeb also screened titles and abstracts.

Author Contributions

A.C.B. and H.K.B. developed the study concept. S.S. contributed to developing and conducting the database search and coordinated the screening of titles and abstracts. A.C.B. and R.S.L. also screened titles and abstracts. All authors conducted the full-text screening and data extraction. A.C.B., H.K.B. and R.S.L. conducted the data analyses and contributed to the write-up and review of the manuscript. S.S. provided feedback on the manuscripts. The funders had no involvement in the data extraction, analysis and writing of the manuscript.

Declaration of Conflicting Interests

The author(s) declared no potential conflicts of interest with respect to the research, authorship and/or publication of this article.

Funding

The author(s) disclosed receipt of the following financial support for the research, authorship and/or publication of this article: A.C.B. is supported by a Canadian Institutes for Health Research (CIHR) Ontario HIV Treatment Network (OHTN) New Investigator Award; Rachel S. Lee, Catherine Moses and Priya Prabhakar are supported by a CIHR Operating Grant (CBA 144834); H.K.B. is supported by a Tier 2 Canada Research Chair; S.S. is supported by a Canadian Institutes for Health Research (CIHR) Operating Grant (CBA 144384) and from Dr Brown’s Canada Research Chair.

ORCID iD

Anita C Benoit

Supplemental Material

Supplemental material for this article is available online.

References

Alfred

(2009) Colonialism and state dependency. International Journal of Indigenous Health 5: 42–60.

Antonio

Chung-Do

(2015) Systematic review of interventions focusing on Indigenous adolescent mental health and substance use. American Indian and Alaska Native Mental Health Research 22: 36–56.

Armijo-Olivo

Stiles

Hagen

, et al. (2012) Assessment of study quality for systematic reviews: A comparison of the Cochrane Collaboration Risk of Bias Tool and the Effective Public Health Practice Project Quality Assessment Tool: Methodological research. Journal of Evaluation Clinical Practice 18: 12–18.

Auger

Howell

Gomes

(2016) Moving toward holistic wellness, empowerment and self-determination for Indigenous peoples in Canada: Can traditional Indigenous health care practices increase ownership over health and health care decisions? Canadian Journal of Public Health 107: e393–e398.

Auger

(2016) Cultural continuity as a determinant of Indigenous peoples’ health: A metasynthesis of qualitative research in Canada and the United States. The International Indigenous Policy Journal 7: 7500.

Australian Government (2019) Australia’s long term national health plan to build the world’s best health system. Report, Department of Health, Canberra, ACT, Australia, August. Available at: www.health.gov.au/sites/default/files/australia-s-long-term-national-health-plan_0.pdf (accessed 17 May 2021).

Bassett

Buchwald

Manson

(2014) Posttraumatic stress disorder and symptoms among American Indians and Alaska Natives: A review of the literature. Social Psychiatry and Psychiatric Epidemiology 49: 417–433.

Baxter

Kokaua

Wells

, et al. (2006) Ethnic comparisons of the 12 month prevalence of mental disorders and treatment contact in Te Rau Hinengaro: The New Zealand Mental Health Survey. Australian and New Zealand Journal of Psychiatry 40: 905–913.

Beals

Novins

Whitesell

, et al. (2005) Prevalence of mental disorders and utilization of mental health services in two American Indian reservation populations: Mental health disparities in a national context. American Journal of Psychiatry 162: 1723–1732.

10.

Beckstead

Lambert

DuBose

, et al. (2015) Dialectical behavior therapy with American Indian/Alaska Native adolescents diagnosed with substance use disorders: Combining an evidence based treatment with cultural, traditional, and spiritual beliefs. Addictive Behaviors 51: 84–87.

11.

Bennett

(2009) Te huanga o te ao Maori: Cognitive behavioural therapy for Maori clients with depression: Development and evaluation of a culturally adapted treatment programme. PhD, Massey University, Wellington, New Zealand.

12.

Bennett

Flett

Babbage

(2014) Culturally adapted cognitive behaviour therapy for Māori with major depression. The Cognitive Behaviour Therapist 7: e20.

13.

Bowen

Powers

Russo

, et al. (2020) Implementing collaborative care to reduce depression for rural native American/Alaska native people. BMC Health Services Research 20: 34.

14.

Brascoupé

Waters

(2009) Cultural safety: Exploring the applicability of the concept of cultural safety to Aboriginal health and community wellness. International Journal of Indigenous Health 5: 6–41.

15.

Brave Heart

MYH

Chase

Myers

, et al. (2020) Iwankapiya American Indian pilot clinical trial: Historical trauma and group interpersonal psychotherapy. Psychotherapy 57: 184–196.

16.

Calma

Dudgeon

Bray

(2017) Aboriginal and Torres Strait Islander social and emotional wellbeing and mental health. Australian Psychologist 52: 255–260.

17.

Canadian Institutes of Health Research, Natural Sciences and Engineering Research Council of Canada and Social Sciences and Humanities Research Council (2018) Chapter 9: Research involving the First Nations, Inuit and Métis Peoples of Canada. Ottawa, ON, Canada. Available at: https://ethics.gc.ca/eng/documents/tcps2-2018-en-interactive-final.pdf (accessed 7 November 2021).

18.

Chandler

Lalonde

(1998) Cultural continuity as a hedge against suicide in Canada’s First Nations. Transcultural Psychiatry 35: 191–219.

19.

Curtis

Jones

Tipene-Leach

, et al. (2019) Why cultural safety rather than cultural competency is required to achieve health equity: A literature review and recommended definition. International Journal for Equity in Health 18: 174.

20.

Dickerson

Venner

Duran

, et al. (2014) Drum-assisted recovery therapy for Native Americans (DARTNA): Results from a pretest and focus groups. American Indian and Alaska Native Mental Health Research 21: 35–58.

21.

Faber

Fonseca

(2014) How sample size influences research outcomes. Dental Press Journal of Orthodontics 19: 27–29.

22.

First Nations Health Authority (2018) FNHA’s policy on mental health and wellness. Report, Vancouver, BC, Canada. Available at: www.fnha.ca/WellnessSite/WellnessDocuments/FNHA-Policy-on-Mental-Health-and-Wellness.pdf (accessed 1 May 2021).

23.

Gee

Dudgeon

Schultz

, et al. (2014) Part 1: Historical Contexts—Aboriginal and Torres Strait Islander Social and Emotional Wellbeing. Commonwealth of Australia. Available at: www.telethonkids.org.au/globalassets/media/documents/aboriginal-health/working-together-second-edition/working-together-aboriginal-and-wellbeing-2014.pdf (accessed 1 May 2021).

24.

Gray

Mays

Wolf

, et al. (2010) A culturally focused wellness intervention for American Indian women of a small southwest community: Associations with alcohol use, abstinence self-efficacy, symptoms of depression, and self-esteem. American Journal of Health Promotion 25: e1–e10.

25.

Guillemin

Gillam

Barnard

, et al. (2016) ‘We’re checking them out’: Indigenous and non-Indigenous research participants’ accounts of deciding to be involved in research. International Journal for Equity in Health 15: 8.

26.

Harding

Oetzel

(2019) Implementation effectiveness of health interventions for indigenous communities: A systematic review. Implementation Science 14: 76.

27.

Harfield

Pearson

Morey

, et al. (2020) Assessing the quality of health research from an Indigenous perspective: The Aboriginal and Torres Strait Islander quality appraisal tool. BMC Medical Research Methodology 20: 79.

28.

Hatcher

Coupe

Durie

, et al. (2011) Te Ira Tangata: A zelen randomised controlled trial of a treatment package including problem solving therapy compared to treatment as usual in Maori who present to hospital after self harm. Trials 12: 117.

29.

Hatcher

Coupe

Wikiriwhi

, et al. (2016) Te Ira Tangata: A Zelen randomised controlled trial of a culturally informed treatment compared to treatment as usual in Māori who present to hospital after self-harm. Social Psychiatry and Psychiatric Epidemiology 51: 885–894.

30.

Hawkes

Pollock

Judd

, et al. (2017) Ngapartji Ngapartji: Finding ethical approaches to research involving Indigenous Peoples, Australian perspectives. ab-Original: Journal of Indigenous Studies and First Nations and First Peoples’ Cultures 1: 17–41.

31.

Hayward

Sjoblom

Sinclair

, et al. (2021) A new era of Indigenous research: Community-based Indigenous research ethics protocols in Canada. Journal of Empirical Research on Human Research Ethics 16: 403–417.

32.

Higgins

JPT

Green

(2011) Cochrane Handbook for Systematic Reviews of Interventions. Version 5.1.0 (Updated March 2011). The Cochrane Collaboration. Available at: https://handbook-5-1.cochrane.org/ (accessed 1 May 2021).

33.

Hoffmann

Glasziou

Boutron

, et al. (2014) Better reporting of interventions: Template for intervention description and replication (TIDieR) checklist and guide. British Medical Journal 348: g1687.

34.

Huria

Palmer

Pitama

, et al. (2019) Consolidated criteria for strengthening reporting of health research involving Indigenous Peoples: The CONSIDER statement. BMC Medical Research Methodology 19: 173.

35.

Hyett

Marjerrison

Gabel

(2018) Improving health research among Indigenous Peoples in Canada. Canadian Medical Association Journal (CMAJ) 190: E616–E621.

36.

Kelly

Dudgeon

Gee

, et al. (2009) Living on the Edge: Social and Emotional Wellbeing and Risk and Protective Factors for Serious Psychological Distress among Aboriginal and Torres Strait Islander People. Cooperative Research Centre for Aboriginal Health. Available at: www.indigenouspsychology.com.au/Assets/Files/AIPA-Living-on-the-Edge-web.pdf (accessed 17 May 2021).

37.

Kirmayer

Brass

Tait

(2000) The mental health of Aboriginal Peoples: Transformations of identity and community. The Canadian Journal of Psychiatry 45: 607–616.

38.

Korn

Logsdon

Polissar

, et al. (2009) A randomized trial of a CAM therapy for stress reduction in American Indian and Alaskan Native family caregivers. Gerontologist 49: 368–377.

39.

Kwaymullina

(2016) Research, ethics and Indigenous Peoples: An Australian Indigenous perspective on three threshold considerations for respectful engagement. AlterNative: An International Journal of Indigenous Peoples 12: 437–449.

40.

Leske

Harris

Charlson

, et al. (2016) Systematic review of interventions for Indigenous adults with mental and substance use disorders in Australia, Canada, New Zealand and the United States. Australian and New Zealand Journal of Psychiatry 50: 1040–1054.

41.

Liberati

Altman

Tetzlaff

, et al. (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: Explanation and elaboration. Journal of Clinical Epidemiology 62: e1–e34.

42.

MacDonald

Ford

Cunsolo Willox

, et al. (2013) A review of protective factors and causal mechanisms that enhance the mental health of Indigenous circumpolar youth. International Journal of Circumpolar Health 72: 1–18.

43.

Markwick

Ansari

Sullivan

, et al. (2014) Inequalities in the social determinants of health of Aboriginal and Torres Strait Islander People: A cross-sectional population-based study in the Australian state of Victoria. International Journal for Equity in Health 13: 91–103.

44.

Mathieson

Mihaere

Collings

, et al. (2012) Maori cultural adaptation of a brief mental health intervention in primary care. Journal of Primary Health Care 4: 231–238.

45.

Ministry of Health—Manatu Hauora (2020a) Annual update of key results 2019/20: New Zealand health survey. Available at: www.health.govt.nz/publication/annual-update-key-results-2019-20-new-zealand-health-survey (accessed 17 May 2021).

46.

Ministry of Health—Manatu Hauora (2020b) Work programme 2019/20. Available at: www.health.govt.nz/about-ministry/what-we-do/work-programme-2019-20 (accessed 17 May 2021).

47.

Nadalin

Maar

Ashbury

, et al. (2010) Issues in the recruitment and retention of Aboriginal health research participants in Canada. Aboriginal Policy Research Consortium International 40: 143–160.

48.

Nagel

Robinson

Condon

, et al. (2009) Approach to treatment of mental illness and substance dependence in remote Indigenous communities: Results of a mixed methods study. Australian Journal of Rural Health 17: 174–182.

49.

National Health and Medical Research Council (2018) Ethical conduct in research with Aboriginal and Torres Strait Islander Peoples and communities: Guidelines for researchers and stakeholders. Canberra, ACT, Australia. Available at: https://www.nhmrc.gov.au/about-us/resources/ethical-conduct-research-aboriginal-and-torres-strait-islander-peoples-and-communities# (accessed 7 November 2021).

50.

Nielsen

Robyn

(2003) Colonialism and criminal justice for Indigenous Peoples in Australia, Canada, New Zealand and the United States of America. Indigenous Nations Journal 4: 29–45.

51.

O’Neill

Fraser

Kitchenham

, et al. (2018) Hidden burdens: A review of intergenerational, historical and complex trauma, implications for Indigenous families. Journal of Child & Adolescent Trauma 11: 173–186.

52.

Paradies

(2016) Colonisation, racism and Indigenous health. Journal of Population Research 33: 83–96.

53.

Pearson

Kaysen

Huh

, et al. (2019) Randomized control trial of culturally adapted cognitive processing therapy for PTSD substance misuse and HIV sexual risk behavior for Native American women. AIDS and Behavior 23: 695–706.

54.

Pollok

van Agteren

Chong

, et al. (2018) Evaluation of existing experimental evidence for treatment of depression in Indigenous populations: A systematic review. Australian Journal of Psychology 70: 305–317.

55.

Pomerville

Burrage

Gone

(2016) Empirical findings from psychotherapy research with Indigenous populations: A systematic review. Journal of Consulting and Clinical Psychology 84: 1023–1038.

56.

Public Health Agency of Canada (2020) Public Health Agency of Canada’s departmental plan 2020-2021. Report, Ottawa, ON, Canada. Report no. HP2-26E-PDF. Available at: www.canada.ca/content/dam/phac-aspc/documents/corporate/transparency/corporate-management-reporting/reports-plans-priorities/2020-2021-departmental-plan/phac_2020-21_dp_main_report-eng.pdf (accessed 17 May 2021).

57.

Rotenberg

(2016) Aboriginal Peoples Survey: Social determinants of health for the off-reserve First Nations population, 15 years of age and older, 2012. Report, Ottawa, ON, Canada. Report no. 978-0-660-04308-1. Available at: www150.statcan.gc.ca/n1/en/pub/89-653-x/89-653-x2016010-eng.pdf?st=VDH3rLnu (accessed 17 May 2021).

58.

Sabbioni

Feehan

Nicholls

, et al. (2018) Providing culturally informed mental health services to Aboriginal youth: The YouthLink model in Western Australia. Early Intervention in Psychiatry 12: 987–994.

59.

Schnarch

(2004) Ownership, control, access and possession (OCAP) or self-determination applied to research. International Journal of Indigenous Health 1: 80–95.

60.

Shand

Ridani

Tighe

, et al. (2013) The effectiveness of a suicide prevention app for Indigenous Australian youths: Study protocol for a randomized controlled trial. Trials 14: 396.

61.

Smylie

(2005) The ethics of research involving Canada’s Aboriginal populations. Canadian Medical Association Journal (CMAJ) 172: 977–979.

62.

Statistics Canada (2016) Table 13-10-0099-01. Health indicator profile, by Aboriginal identity and sex, age-standardized rate, four year estimates. Available at: www150.statcan.gc.ca/t1/tbl1/en/tv.action?pid=1310009901 (accessed 17 May 2021).

63.

Sun

Buys

(2013a) Improving Aboriginal and Torres Strait Islander Australians’ well-being using participatory community singing approach. International Journal on Disability and Human Development 12: 305–316.

64.

Sun

Buys

(2013b) Participatory community singing program to enhance quality of life and social and emotional well-being in Aboriginal and Torres Strait Islander Australians with chronic diseases. International Journal on Disability and Human Development 12: 317–323.

65.

Tighe

Shand

Ridani

, et al. (2017) Ibobbly mobile health intervention for suicide prevention in Australian Indigenous youth: A pilot randomised controlled trial. BMJ Open 7: e013518.

66.

Titov

Dear

Staples

, et al. (2017) The first 30 months of the MindSpot Clinic: Evaluation of a national e-mental health service against project objectives. Australian and New Zealand Journal of Psychiatry 51: 1227–1239.

67.

Titov

Schofield

Staples

, et al. (2019) A comparison of Indigenous and non-Indigenous users of MindSpot: An Australian digital mental health service. Australasian Psychiatry 27: 352–357.

68.

Tosa

Tafoya

Sando

, et al. (2018) RezRIDERS: A tribally-driven, extreme sport intervention and outcomes. Journal of Indigenous Social Development 7: 20–41.

69.

Tsosie

Nannauck

Buchwald

, et al. (2011) Staying connected: A feasibility study linking American Indian and Alaska Native trauma survivors to their tribal communities. Psychiatry 74: 349–361.

70.

Hadjipavlou

Dehoney

, et al. (2019) Partnering with Indigenous Elders in primary care improves mental health outcomes of inner-city Indigenous patients: Prospective cohort study. Canadian Family Physician 65: 274–281.

71.

Tuck

(2009) Suspending damage: A letter to communities. Harvard Education Review 79: 409–428.

72.

Tuck

Yang

(2012) Decolonization is not a metaphor. Decolonization: Indigeneity, Education & Society 1: 1–40.

73.

United Nations (2009) State of the World’s Indigenous Peoples. New York: Department of Economic and Social Affairs. Available at: www.un.org/esa/socdev/unpfii/documents/SOWIP/en/SOWIP_web.pdf (accessed 17 May 2021).

74.

US Department of Health and Human Services (2020) HHS action plan to reduce racial and ethnic health disparities: A nation free of disparities in health and health care. Report, Rockville, MD. Available at: www.minorityhealth.hhs.gov/assets/pdf/hhs/HHS_Plan_complete.pdf (accessed 17 May 2021).

75.

Varcoe

Browne

Ford-Gilboe

, et al. (2017) Reclaiming our spirits: Development and pilot testing of a health promotion intervention for Indigenous women who have experienced intimate partner violence. Research in Nursing & Health 40: 237–254.

76.

Varcoe

Ford-Gilboe

Browne

, et al. (2021) The efficacy of a health promotion intervention for Indigenous women: Reclaiming our spirits. Journal of Interpersonal Violence 36: 1–31.

77.

Wilson

de la Ronde

Brascoupé

, et al. (2013) Chapter 8: Changing outcomes through culturally competent care. The Society of Obstetricians and Gynaecologists of Canada. Journal of Obstetrics and Gynaecology Canada 35: S38–S41.

Supplementary Material

Please find the following supplemental material available below.

For Open Access articles published under a Creative Commons License, all supplemental material carries the same license as the article it is associated with.

For non-Open Access articles published, all supplemental material carries a non-exclusive license, and permission requests for re-use of supplemental material or any part of supplemental material shall be sent directly to the copyright owner as specified in the copyright notice associated with the article.

0.00 MB

0.09 MB