Maternal Serum CA125 is Not a Second Trimester Marker for Down's Syndrome

Check JH Kosrow N Vaze M Wapner R Seefried L . Very high CA125 levels during early first trimester in three cases of spontaneous abortion with chromosomal abnormalities. Am J Obstet Gynecol 1990; 162: 674–5.

Wald NJ Cuckle HS Densem JW Maternal serum screening for Down's syndrome in early pregnancy. BMJ 1988; 297: 883–7.

Cuckle HS Wald NJ Goodburn SF Sneddon J Amess JAL Dunn SC . Measurement of activity of urea resistant neutrophil alkaline phosphatase as an antenatal screening test for Down's syndrome. BMJ 1990; 301: 1024–6.