A new membrane–based device is described for the quantitative separation of plasma from blood cells using neither centrifugation nor pipetting. The concentration of cholesterol in the isolated plasma was determined using a newly developed instrument, the Primetest. The results were in good agreement with those obtained in the hospital laboratory.
US Patent 4.798.845 (17 January 1989), HDW Roesink, DM Koenhen, MHV Mulder and CA Smolders (assigned to X-FLOW BV, Enschede, The Netherlands).
3.
AllainCPoonLSChanCSGRichmondWFuPC. Enzymatic determination of total serum cholesterol. Clin Chem1974; 20: 470–5.
4.
PassingHBablokW. A new biometrical procedure for testing the equality of measurements from two different analytical methods. J Clin Chem Clin Biochem1983; 21: 709–20.
5.
FraserCGFogartyY. Interpreting laboratory results. Br Med J1989; 298: 1659–60.
6.
LilfordRJ. Interpreting laboratory results. Br Med J1989; 299: 322–3.
7.
FordRP. Essential data derived from biological variation for establishment and use of lipid analyses. Ann Clin Biochem1989; 26: 281–5.
8.
KochTRMahtaULeeH. Bias and precision of cholesterol analysis by physician's office analyzers. Clin Chem1987; 33: 2262–70.
9.
BoydJC. Accuracy in cholesterol assays. Clin Chem1988; 34: 2194–5.
10.
BroughtonPMGBullockDGCrambR. Quality of plasma cholesterol measurements in primary care. Br Med J1989; 298: 297–8.
