The current report documents the rare clinical presentation of an imported acute and isolated glottic paracoccidioidomycosis. We discuss the diagnosis, pathogenesis, and treatment of this laryngeal disease, emphasizing the role of modern antifungal treatment, and review the relevant literature.
de AlmeidaOPJorgeJScullyCBozzoL. Oral manifestations of paracoccidioidomycosis (South American blastomycosis). Oral Surg Oral Med Oral Pathol Oral Radiol Endod1991;72:430–5.
2.
DelgadoWAguirreJM. Las micosis orales en la era del sida. Rev Iberoam Micol1997;14:14–22.
3.
Sant'AnnaGDMauriMArrarteJLCamargoHJr. Laryngeal manifestations of paracoccidioidomycosis (South American blastomycosis). Arch Otolaryngol Head Neck Surg1999;125:1375–8.
4.
SalazarMERestrepoAStevensDA. Inhibition by estrogens of conidium-to-yeast conversion in the fungus Paracoccidioides brasiliensis. Infect Immun1988;56:711–3.
5.
AjelloLPolonelliL. Imported paracoccidioidomycosis: A public health problem in non-endemic areas. Eur J Epidemiol1985;1:160–5. [Erratum in Eur J Epidemiol 1986;2:81.]
6.
PayneJKoopmannCFJr. Laryngeal carcinoma — Or is it laryngeal blastomycosis. Laryngoscope1984;94:608–11.
7.
ArgañarazM MaymóLuqueAGToselloMEAPerezJ. Paracoccidioidomycosis and larynx carcinoma. Mycoses2003;46:229–32.
8.
TristanoAGDíazL. A case of laryngeal paracoccidioidomycosis masquerading as chronic obstructive lung disease. South Med J2007;100:709–11.
9.
Del NegroGMBGarciaNMRodriguesEG. The sensitivity, specificity and efficiency values of some serological tests used in the diagnosis of paracoccidioidomycosis. Rev Inst Med Trop Sao Paulo1991;33:277–80.
10.
GomesGMCisalpinoPSTabordaCPde CamargoZP. PCR for diagnosis of paracoccidioidomycosis. J Clin Microbiol2000;38:3478–80.
11.
LoehrlTASmithTL. Inflammatory and granulomatous lesions of the larynx and pharynx. Am J Med2001;111 (suppl 8A):113S–117S.
12.
VrabecDP. Fungal infections of the larynx. Otolaryngol Clin North Am1993;26:1091–114.
13.
ComoJADismukesWE. Oral azole drugs as systemic antifungal therapy. N Engl J Med1994;330:263–72.
