Management of Hypercalcemic Crisis due to Primary Hyperparathyroidism During Pregnancy

Abstract

Primary hyperparathyroidism is the third most common endocrine disorder following diabetes and thyroid disease. Women are affected by primary hyperparathyroidism twice as often as men. The first reported case of hyperparathyroidism during pregnancy was in 1931. More recent data suggests that hyperparathyroidism during pregnancy is diagnosed in .5-1.4% of women. Symptoms of primary hyperparathyroidism, such as fatigue, lethargy, and proximal muscle weakness are nonspecific and could be mistaken as complaints naturally present during pregnancy; however, maternal complications in patients with hyperparathyroidism can be as high as 67%. We present a case of a pregnant patient who presented in hypercalcemic crisis with a concomitant diagnosis of primary hyperparathyroidism.