Prevention of Ischemic Stroke by Vaccination: A Missed Challenge?

1 European Stroke Organisation (ESO) Executive Committee; ESO Writing Committee. Guidelines for management of ischaemic stroke and transient ischaemic attack 2008. Cerebrovasc Dis 2008; 25:457–507.

2 Small DL Morley P Buchan AM . Current and experimental treatment of stroke; in Davis KL Charney D Coyle JT Nemeroff C (eds): Neuropsychopharmacology: The Fifth Generation of Progress. USA: American College of Neuropsychopharmacology, 2002: 1327–38.

3 Caligiuri G Khallou-Laschet J Vandaele M . Phosphorylcholine-targeting immunization reduces atherosclerosis. J Am Coll Cardiol 2007; 50:540–6.

4 During MT Symes CW Lawlor PA . An oral vaccine against NMDAR1 with efficacy in experimental stroke and epilepsy. Science 2000; 25:1453–60.

5 Abciximab Emergent Stroke Treatment Trial (AbESTT) Investigators. Emergency administration of abciximab for treatment of patients with acute ischemic stroke: results of a randomized phase 2 trial. Stroke 2005; 36:880–90.

6 Bang D Kent SB . His6 tag-assisted chemical protein synthesis. Proc Natl Acad Sci USA 2005; 102:5014–9.

7 Dawson PE Kent SB . Synthesis of native proteins by chemical ligation. Annu Rev Biochem 2000; 69:923–60.

8 Blank M Barzilai O Shoenfeld Y . Molecular mimicry and autoimmunity. Clin Rev Allergy Immunol 2007; 32:111–8.