Abstract
Quantitative measurement of sound-induced discomfort and pain thresholds showed mat migraineurs (n = 65) were significantly more sensitive than headache-free controls (n = 80), both during and outside attack (p <0.0001). Patients tested with head pain had lower thresholds than those tested without pain (p <0.01). Migraine with and without aura did not differ as to sound sensitivity. There were no significant differences in thresholds between the symptomatic and nonsymptomatic sides (p ≥ 0.78). Patients with unilateral headache or pain of pulsating character were more sensitive than those with bilateral headache or pressing pain (p <0.05). Phonophobia did not correlate significantly with duration, frequency, or severity of attacks. The main results were in accordance with a questionnaire study concerning subjective evaluation of sound sensitivity. Similarities between phonophobia and photophobia in migraine provide evidence mat both phenomena share a common pathophysiological mechanism in this condition.
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