This work demonstrates the principle of a novel cancer therapeutic method using magnetic fluids to block the blood supply to a tumor in order to starve it. Plastic tubes are used to simulate the simplest blood network. The sealing effect to the fluid flow is easily achieved at low particle concentrations with strong pressure resistance and reasonable sealing times at low flow rate (Q = 0.078 ml/min). At high flow rate (Q > 0.62 ml/min), oscillations in pressure and step increases in weight of the fluid are found.
Get full access to this article
View all access options for this article.
References
1.
1. U. Hdfeli, W. SchUtt, J. Teller and M. Zborowski (Eds), Scientific and Clinical Applications of Magnetic Carriers (Plenum Press, New York and London, 1997).
2.
2. Long Beach, CA Press-Telegram, May 5, 1998; also "Angiogenesis and Metastatic Growth,"Advances in Oncology, August 1996, Vol. 12No. 3.
3.
3. Y. Zhu, M. McNeary, and N. Breslin, Proc. 6th Int'l Conf. on Electrorheological Fluids, Magnetorheological Suspensions and Their Applications, Yonezawa, Japan, July 22-25, 1997, K. Koyama and M. Nakano eds. (World Scientific, Singapore, 1998).
4.
4. R. Sheng, G. A. Flores, and J. Liu.J. Magnetism and Mag. Mat., 194:167-175 (1999).
5.
5. R. L. Whitmore. Rheology of the Circulation, Pergamon Press, Oxford, 1968.
6.
6. C. L. Schauf, D. F. Moffett, and S. B. Moffett. Human Physiology: Foundations and Frontiers, (Times-Mirror/Mosby Coll. Publ. St. Louis, 1990).
7.
7. M. Chaker, N. Breslin and J. Liu, "Influence on Rheology of Static and Dynamic Structures in Model Magnetorheological Fluids."
8.
8. G. A. Flores, J. Liu, M. Mohebi and N. Jamasbi, "Magnetic-Field Induced Non-Equilibrium Structures in a Ferrofluid Emulsion,"Phys. Rev. E., 59:751-762 (1999).
