Malignant mesotheliomas are aggressive neoplasms, which are rare, especially in the pediatric population. Unlike malignant mesotheliomas most commonly seen in adults, those of the peritoneum and testicle in children do not appear to be as strongly associated with direct asbestos exposure and have an unpredictable biologic behavior requiring individual treatment strategies. There may, however, be an association between children with malignant mesothelioma and asbestos-exposed household members. Herein, we report a very rare case of a 15-year-old male adolescent who presented with testicular pain, redness, and swelling and was found to have testicular malignant mesothelioma with retroperitoneal nodal and peritoneal metastases.
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