Abstract
Background
There are differing results in the literature regarding the relationship between atopic dermatitis (AD) and peripheral blood leukocyte profiles.
Objective
The aim of the study was to investigate the relationship between AD, blood immune cell profiles, and disease severity.
Methods
One hundred AD patients aged 1 month to 18 years without any history of infection or systemic disease were enrolled as the study group. Serum concentration levels of total immunoglobulin E, calculated blood leukocyte profiles, and AD index severity scoring were calculated for statistical comparison.
Results
The differences between the groups for neutrophil-lymphocyte ratio and eosinophil-lymphocyte ratio were statistically different. However, there was no statistically significant correlation between the investigated parameters and AD index severity scoring.
Conclusions
Although significant differences were found in some of the parameters between the groups, unfortunately, the lack of correlation between the parameters investigated and the disease severity index restricts their use in clinical practice.
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