Molecular Testing for Indeterminate Nodules: Is It Necessary? Introduction

Abstract

Introduction:

Molecular testing for indeterminate thyroid nodules has gained popularity in the United States. The utility and cost-effectiveness of the current generations of molecular tests remain debated.

Materials and Methods:

This is a brief introduction to the Counterpoint Debate weighing the pros and cons of molecular testing for indeterminate thyroid nodules.

Results:

The current versions of Afirma Gene Sequencing Classifier and Thyroseq v3 have improved diagnostic performance compared with prior test versions. Their utility must be examined in each practice setting, considering factors such as the prevalence of malignancy. Molecular testing may also have a future role in prognosticating oncologic outcomes for thyroid cancer.

Conclusions:

Arguments can be made in favor of and against routine molecular testing for indeterminate thyroid nodules.

No competing financial interests exist.

Runtime of video: 2 mins 1 sec