Abstract

Get full access to this article
View all access options for this article.
References
1.
Szarka
N.
,
Pabbidi
M.R.
,
Amrein
K.
,
Czeiter
E.
,
Berta
G.
,
Pohoczky
K.
,
Helyes
Z.
,
Ungvari
Z.
,
Koller
A.
,
Buki
A.
, and
Toth
P.
(2018 ). Traumatic brain injury impairs myogenic constriction of cerebral arteries: role of mitochondria-derived H2O2 and TRPV4-dependent activation of BKCa channels . J Neurotrauma , 35 , 930 –939 .
2.
Suresh
K.
,
Servinsky
L.
,
Jiang
H.
,
Bigham
Z.
,
Yun
X.
,
Kliment
C.
,
Huetsch
J.C.
,
Damarla
M.
, and
Shimoda
L.A.
(2018 ). Reactive oxygen species induced Ca2+ influx via TRPV4 and microvascular endothelial dysfunction in the SU5416/hypoxia model of pulmonary arterial hypertension . Am. J. Physiol. Lung. Cell. Mol. Physiol. , 5 , 893 –907 .
3.
Suresh
K.
,
Servinsky
L.
,
Reyes
J.
,
Baksh
S.
,
Undem
C.
,
Caterina
M.
,
Pearse
D.B.
, and
Shimoda
L.A.
(2015 ). Hydrogen peroxide-induced calcium influx in lung microvascular endothelial cells involves TRPV4 . Am. J. Physiol. Lung Cell Mol. Physiol. , 309 , L1467 –L1477 .
4.
Thorneloe
K.S.
,
Cheung
M.
,
Bao
W.
,
Alsaid
H.
,
Lenhard
S.
,
Jian
M.Y.
,
Costell
M.
,
Maniscalco-Hauk
K.
,
Krawiec
J.A.
,
Olzinski
A.
,
Gordon
E.
,
Lozinskaya
I.
,
Elefante
L.
,
Qin
P.
,
Matasic
D.S.
,
James
C.
,
Tunstead
J.
,
Donovan
B.
,
Kallal
L.
,
Waszkiewicz
A.
,
Vaidya
K.
,
Davenport
E.A.
,
Larkin
J.
,
Burgert
M.
,
Casillas
L.N.
,
Marquis
R.W.
,
Ye
G.
,
Eidam
H.S.
,
Goodman
K.B.
,
Toomey
J.R.
,
Roethke
T.J.
,
Jucker
B.M.
,
Schnackenberg
C.G.
,
Townsley
M.I.
,
Lepore
J.J.
, and
Willette
R.N.
An orally active TRPV4 channel blocker prevents and resolves pulmonary edema induced by heart failure . Sci. Transl. Med. , 4 , 159ra148.
5.
Dong
Q.
,
Li
J.
,
Wu
Q.F.
,
Zhao
N.
,
Qian
C.
,
Ding
D.
,
Wang
B.B.
,
Chen
L.
,
Guo
K.F.
,
Fu
D.
,
Han
B.
,
Liao
Y.H.
, and
Du
Y.M.
(2017 ). Blockage of transient receptor potential vanilloid 4 alleviates myocardial ischemia/reperfusion injury in mice . Sci. Rep. , 7 , 42678 .
