KyrilisFL, SemchonokDA, SkalidisI, et al.Integrative structure of a 10-megadalton eukaryotic pyruvate dehydrogenase complex from native cell extracts. Cell Rep., 2021; 34: 108727. DOI: 10.1016/j.celrep.2021.108727.
2.
SkalidisI, TütingC, KastritisPL. Unstructured regions of large enzymatic complexes control the availability of metabolites with signaling functions. Cell Commun. Signal. 2020; 18(1): 136. DOI: 10.1186/s12964-020-00631-9
3.
KyrilisFL, BelapureJ, KastritisPL. Detecting Protein Communities in Native Cell Extracts by Machine Learning: A Structural Biologist's Perspective. Front. Mol. Biosci., 2021; 8: 660542. DOI: 10.3389/fmolb.2021.660542.
4.
TütingC, KyrilisFL, MüllerJ, et al.Cryo-EM snapshots of a native lysate provide structural insights into a metabolon-embedded transacetylase reaction. Nat. Commun. 2021; 12: 6933. DOI: 10.1038/s41467-021-27287-4.