Order of Precedence and Age of Y-DNA Haplotypes

Abstract

A simple method, inspired by procedures used in the physics of nuclear multi-fragmentation, allows for establishing order of precedence and age of pairs of haplotypes separated by one mutation. For both haplotypes of the pair, searches for existing haplotypes, differing by increasing number of mutations, are carried out using a database. The resulting ratios of frequencies of haplotypes, found at given mutation distances, are compared to calculated probability ratios. The order of precedence and age of the pair of haplotypes can be deduced when the resulting ratios follow a hyperbolic dependence. The method can be used with relatively small and not necessarily complete samples, using publicly accessible databases.

Get full access to this article

View all access options for this article.

References

Gusmao

et al. 2005. Mutation rates at Y chromosome specific microsatellites. Hum. Mutat., 26:520–528.

Klyosov

A.A.

2009. DNA Genealogy, mutation rates, and some historical evidences written in Y-chromosome. I. Basic principles and the method. J. Genetic Genealogy, 5:186–216.

Klyosov

2010. Main puzzle on relations of Indo-European and Turkic language families and an attempt to solve it using DNA-genealogy: A view of non-linguist. Proceedings of Russian Academy of DNA genealogy 32–56 (in Russian).

Veselsky

2005. Isotopic trends in nuclear multi-fragmentation. Physics of Particles and Nuclei, 36:213–232.