Acupuncture is increasingly being used in the management of a wide range of symptoms. Despite decades of acupuncture research, a significant gap remains in translating evidence into specific and clear clinical guidelines for acupuncture practice. In this article, the authors discuss the gap between acupuncture research and clinical practice and exploring options to overcome the limitations of current clinical research of acupuncture.
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References
1.
ZiaFZ, OlakuO, BaoT, et al.The National Cancer Institute's Conference on acupuncture for symptom management in oncology: State of the science, evidence, and research gaps. J Natl Cancer Inst Monogr. 2017; 2017(52):lgx005.
2.
MaliakalP, LedfordA. Electrolyte and protein imbalance following anti-EGFR therapy in cancer patients: A comparative study. Exp Ther Med. 2010; 1(2):307–311.
3.
GarciaMK, Graham-GettyL, HaddadR, et al.Systematic review of acupuncture to control hot flashes in cancer patients. Cancer. 2015; 121(22):3948–3958.
4.
GarciaMK, McQuadeJ, LeeR, HaddadR, SpanoM, CohenL. Acupuncture for symptom management in cancer care: An update. Curr Oncol Rep. 2014; 16(12):418.
5.
MacPhersonH, AltmanDG, HammerschlagR, et al.Revised STandards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA): Extending the CONSORT statement. PLoS Med. 2010; 7(6):e1000261.
6.
BaoT, GoloubevaO, PelserC, et al.A pilot study of acupuncture in treating bortezomib-induced peripheral neuropathy in patients with multiple myeloma. Integr Cancer Ther. 2014; 13(5):396–404.
7.
RostockM, JaroslawskiK, GuethlinC, LudtkeR, SchroderS, BartschHH. Chemotherapy-induced peripheral neuropathy in cancer patients: A four-arm randomized trial on the effectiveness of electroacupuncture. Evid Based Complement Alternat Med. 2013; 2013:349653.
8.
ChoJH, ChungWK, KangW, ChoiSM, ChoCK, SonCG. Manual acupuncture improved quality of life in cancer patients with radiation-induced xerostomia. J Altern Complement Med. 2008; 14(5):523–526.
9.
MengZ, GarciaMK, HuC, et al.Randomized controlled trial of acupuncture for prevention of radiation-induced xerostomia among patients with nasopharyngeal carcinoma. Cancer. 2012; 118(3):3337–3344.
10.
SimcockR, FallowfieldL, MonsonK, et al.ARIX: A randomised trial of acupuncture v oral care sessions in patients with chronic xerostomia following treatment of head and neck cancer. Ann Oncol. 2013; 24(3):776–783.
11.
LiuW, QdaisatA, LopezG, et al.Association between acupoint selection, target symptoms, and traditional Chinese medicine diagnosis in real-time clinical practice in a comprehensive cancer center. Integr Cancer Ther. 2020; 19:1534735420928490.
12.
AvisNE, CoeytauxRR, LevineB, IsomS, MorganT. Trajectories of response to acupuncture for menopausal vasomotor symptoms: The Acupuncture in Menopause study. Menopause. 2017; 24(2):171–179.
13.
LiuW, QdaisatA, LopezG, et al.Acupuncture for hot flashes in cancer patients: Clinical characteristics and traditional Chinese medicine diagnosis as predictors of treatment response. Integr Cancer Ther. 2019; 18:1534735419848494.
14.
SchnyerRN, CitkovitzC. Inter-rater reliability in traditional Chinese medicine: Challenging paradigmatic assumptions. J Altern Complement Med. 2019; 25(11):1067–1073.
15.
CaiYH, ShenLS, HuangXL. Progress of the pulse analytical instruments. J Electr Meas Instrum. 2002; 16:55–59.
16.
Model. ZM-IIIC Intelligent TCM Pulse Apparatus Technical and Operating Manual. Shanghai Chinese Medicine Technology Development Company. 1998:1–6.
17.
ChiuCC, LinHS, LinSL. A structural texture recognition approach for medical diagnosis through tongue. Biomed Eng Appl Basis Commun. 1995; 7:143–148.
18.
ChiuCC. A novel approach based on computerized image analysis for traditional Chinese medical diagnosis of the tongue. Comput Methods Programs Biomed. 2000; 61(2):77–89.
19.
KimBH. On the Kyungrak system. Pyongyang, Korea: Foreign Languages Publishing House; 1964.
20.
KovacsFM, GarcíaA, MufraggiN, et al.Migration pathways of hypodermically injected technetium-99m in dogs. Eur Radiol. 2000; 10:1019–1025.
21.
LeeC, SeolSK, LeeBC, HongYK, JeJH, SohKS. Alcian blue staining method to visualize Bonghan threads inside large caliber lymphatic vessels and X-ray microtomography to reveal their microchannels. Lymphat Res Biol. 2006; 4(4):181–190.
22.
LangevinHM, ChurchillDL, CipollaMJ. Mechanical signaling through connective tissue: A mechanism for the therapeutic effect of acupuncture. FASEB J. 2001; 15(12):2275–2282.
23.
LangevinHM. Connective tissue: A body-wide signaling network?. Med Hypotheses. 2006; 66(6):1074–1077.
24.
KonofagouEE, LangevinHM. Using ultrasound to understand acupuncture. Acupuncture needle manipulation and its effect on connective tissue. IEEE Eng Med Biol Mag. 2005; 24(2):41–46.
25.
ZhuZX. The advances and prospect in physiological and biophysical approaches of acupuncture meridian system. Zhen Ci Yan Jiu. 1988; 13(2):81–89.
AhnAC, ParkM, ShawJR, McManusCA, KaptchukTJ, LangevinHM. Electrical impedance of acupuncture meridians: The relevance of subcutaneous collagenous bands. PLoS One. 2010; 5(7):e11907.
28.
LiA-H, ZhangJ-M, XieY-K. Human acupuncture points mapped in rats are associated with excitable muscle/skin–nerve complexes with enriched nerve endings. Brain Res. 2004; 1012(1–2):154–159.
29.
SilbersteinM. The cutaneous intrinsic visceral afferent nervous system: A new model for acupuncture analgesia. J Theor Biol. 2009; 261(4):637–642.
30.
XiangY, HeJY, LiR. Appropriateness of sham or placebo acupuncture for randomized controlled trials of acupuncture for nonspecific low back pain: A systematic review and meta-analysis. J Pain Res. 2018; 11:83–94.
31.
LundI, LundebergT. Are minimal, superficial or sham acupuncture procedures acceptable as inert placebo controls?. Acupunct Med. 2006; 24(1):13–15.
32.
WittCM, VertosickEA, FosterNE, et al.The Effect of Patient Characteristics on Acupuncture Treatment Outcomes: An Individual Patient Data Meta-Analysis of 20,827 Chronic Pain Patients in Randomized Controlled Trials. Clin J Pain. 2019; 35(5):428–434.
33.
LesiG, RazziniG, MustiMA, et al.Acupuncture as an integrative approach for the treatment of hot flashes in women with breast cancer: A prospective multicenter randomized controlled trial (AcCliMaT). J Clin Oncol. 2016; 34(15):1795–1802.
34.
WhiteA. Acupuncture and constitutional diagnosis: Where now?. Acupunct Med. 2011; 29(4):247–248.