Session 8: Stem Cells

Capecchi, M.R. (2001). Generating mice with targeted mutations. Nature Medicine 7, 1086—90.

Pardal, R. , Clarke, M.F. , and Morrison, S.J. (2003). Applying the principles of stem-cell biology to cancer. Nature Reviews Cancer 3, 895—902.

Reya, T. , Morrison S.J. , Clarke, M.F. , and Weissman, I.L. (2001). Stem cells, cancer and cancer stem cells. Nature 414, 105—11.

Rosenthal, N. (2003). Medical progress Prometheus's vulture and the stem-cell promise. The New England Journal of Medicine 349, 267—74.

Wagers, A.J. , and Weissman, I.L. (2004). Plasticity of adult stem cells. Cell 116, 639—48.

Waikel, R. , Kawachi, Y. , Waikel, P.A. , Wang, X.-J. , and Roop, D.R. (2001). Deregulated Expression of c-Myc Depletes Epidermal Stem Cells. Nature Genetics 28, 165—8.

Koster, M.I. , Kim, S. , Mills, A.A. , DeMayo, F. J., and Roop, D. R. (2004). p63 is the molecular switch for initiation of an epithelial stratification program. Genes Dev. 18, 126—31.

Dontu, G. , Abdallah, W. , Foley, J. , Jackson, K. , Kawamura, M. , Clarke, M. , and Wicha, M. (2003). In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes and Development 17, 1253— 70.

Al-Hajj, M. , Wicha, M. , Morrison, S. , and Clarke, M. (2003). Prospective identification and isolation of breast cancer tumorigenic cells. PNAS 100(7), 3983—8.

Dontu, G. , Al-Hajj, M. , Abdallah, W. , Clarke, M. , Wicha, M. (2003). Stem cells in normal breast development and breast cancer. Cell Proliferation 36(Suppl. 1), 59—72.

Dontu, G. , El-Ashry, D. , Wicha, M. (2004). Breast stem/progenitor cells and the estrogen receptor. Trends in Endocrinology and Metabolism, in press.

Al-Hajj, M. , Becker, M. , Wicha, M. , Weissman, I. , Clarke, M. (2004). Therapeutic implications of cancer stem cells. Current Opinion in Genetics and Development 14, 43—7.