Letters to the Editor

Allaben WT , Chou MW , Pegram RA (1991). Dietary restriction and toxicological endpoints: An historical overview. In: Biological Effects of Dietary Restriction . Fishbein L (ed). Springer-Verlag, New York, pp 27 —41.

Hayashi Y. (1995). The merits and demerits of dietary restriction in animal carcinogenicity tests. In: Dietary Restriction: Implications for the Design and Interpretation of Toxicity and Carcinogenicity Studies . Hart RW , Neumann DA , Robertson RT (eds). ILSI Press, Washington, DC.

Kemi M. , Keenan KP , McCoy C. , Hoe C-M. , Soper KA , Ballam GC , van Zwieten MJ (2000). The relative protective effects of moderate dietary restriction versus dietary modifi cation on spontaneou s cardiomyopathy in male Sprague—Dawley rats. Toxicol Pathol 28: 285—296.

Keenan KP , Smith PF , Hertzog P. , Soper KA , Ballam GC , Clark RL (1994). The effects of overfeeding and dietary restriction on Sprague—Dawley rat survival and early pathology biomarkers of aging . Toxicol Pathol 22: 300— 315.

Kemi M. , Keenan KP , McCoy C. , Hoe CM , Soper KA , Ballam GC , vanZwieten MJ (2000). The relative protective effects of moderate dietary restriction versus dietary modifi cation on spontaneous cardiomyopathy in male Sprague—Dawley rats. Toxicol Pathol 28: 285—296.

Keenan KP , Laroque P. , Ballam GC , Soper KA , Dixit R. , Mattson BA , Adams SP , Coleman JB (1996). The effects of diet, ad libitum overfeeding, and moderate dietary restriction on the rodent bioassay: The uncontrolled variable in safety assessment. Toxicol Pathol 24: 757—768.

Keenan KP , Smith PF , Hertzog P. , Soper KA , Ballam GC , Clark RL (1994). The effects of overfeeding and dietary restriction on Sprague—Dawley rat survival and early pathology biomarkers of aging . Toxicol Pathol 22: 300— 315.

Keenan KP , Soper KA , Smith PF , Ballam GC , Clark RL (1995). Diet, overfeeding and moderate dietary restriction in control Sprague—Dawley rats: I. Effects on spontaneous neoplasms . Toxicol Pathol 23: 269—286.

Keenan KP , Soper KA , Hertzog PR , Gumprecht LA , Smith PF , Mattson BA , Ballam GC , Clark RL (1995). Diet, overfeeding and moderate dietary restriction in control Sprague—Dawley rats. II. Effects on age-related proliferative and degenerative lesions. Toxicol Pathol 23: 287—302.

National Research Council, Subcommittee of Laboratory Animal Nutrition (1995). Nutrient requirements of the laboratory rat. In: Nutrient Requirements of Laboratory Animals, 4th ed., pp 11—79. National Academy Press, Washington, DC.

Keenan KP , Ballam GC , Soper KA , Laroque P. , Coleman JB , Dixit R. (1999). Diet, caloric restriction, and the rodent bioassay . Toxicol Sci 52: 24—34.

Giknis ML , Clifford CB (1998). Spontaneous Neoplastic Lesions and Survival in Crl: CD®(SD) BR Rats Maintained on Dietary Restriction. Monograph. Charles River Laboratories, Wilmington , MA.

Masoro EJ (1996). Possible mechanisms underlying the antiaging actions of caloric restriction. Toxicol Pathol 24: 738—741.

Weindruch R. , Walford RL (1988). The Retardation of Aging and Disease by Dietary Restriction. Charles C. Thomas, Springfi eld, IL.

Yu BP (ed) (1994). Modulation of Aging Processes by Dietary Restriction. CRC Press, Boca Raton, FL.