The alpha rhythm of 18 patients with classical migraine (migraine with aura) was studied by EEG spectrum analysis for evidence of neural abnormalities during the asymptomatic period. The temporal relationship of the findings to attacks was studied by serial records in 11 cases. Increased frequency dispersion and frequency asymmetries of the alpha rhythm were found. The records were, however, mostly normal when separated from attacks by at least 10 asymptomatic days. The abnormalities increased significantly before the onset of prodromal symptoms and clearly outlasted the headache phase. The results give evidence of a fluctuating asymmetric neural disorder in classical migraine.
SelbyGLanceJW.Observations on 500 cases of migraine and allied vascular headache.J Neurol Neurosurg Psychiat1960;23:23–32.
2.
SmythVOGWinterAL.The EEG in migraine.Electroencephalogr Clin Neurophysiol1964;16:194–202.
3.
KooiKARajputAHDe JongRN.Significance of the paroxysmal electroencephalogram in the patient with migraine. In:WernerE edProceedings of the 6th International Congress on Electroencephalography and Clinical Neurophysiology.Vienna:Verlag der Wiener Medizinischen Academie,1965:263–5.
4.
SlatterKH.Some clinical and EEG findings in patients with migraine.Brain1968;81:85–98.
5.
HockadayJMWhittyCWM.Factors determining the electroencephalogram in migraine: A study of 560 patients, according to clinical type of migraine.Brain1969;92:769–88.
6.
BarolinGS.Das elektroenzephalogramm beim kopfschmerz.EEG EMG1974;5:67–75.
7.
WesselyPMayrNGoldenbergG.EEG-Befunde bei komplizierter Migräne.EEG EMG1985;16:221–6.
8.
LauritzenMTrojaborgWOlesenJ.EEG during attacks of common and classical migraine.Cephalalgia1981;1:63–6.
9.
SlevinJTFaughtEHannaGRLeeSI.Temporal relationship of EEG abnormalities in migraine to headache and medication.Headache1981;21:251–4.
10.
WesselyPMayrNGoldenbergG.EEG-befunde be komplizierter migräne.EEG EMG1985;16:221–6.
11.
SchlackICourtJ.Das EEG bei vasomotorischen Zephalgien und beim Spannungskopfschmerz.EEG EMG1983;14:17–21.
12.
JonkmanEJLelieveldMHJ.EEG computer analysis in patients with migraine.Electroencephalogr Clin Neurophysiol1981;52:652–5.
13.
PolichJEhlersCLDalessioDJ.Pattern-shift visual evoked reponses and EEG in migraine.Headache1986;26:451–6.
14.
JonkmanEJPoortvlietDCJ.The use of neurometrics in the study of patients with migraine. Abstracts and invited papers, 4th European Congress of EEG and Clinical Neurophysiology.Clin Neurol Neurosurg1987;89--2(suppl I):148.
15.
SchoenenJJamartBDelwaidePJ.Cartographie electroencephalographique dans les migraines en periodes critique et intercritique.Rev EEG Neurophysiol Clin1987;17:289–99.
16.
SchoenenJJamartBDelwaidePJ.Topographic EEG mapping in common and classic migraine during and between attacks. In:Clifford RoseF edAdvances in headache research.John Libbey & Co1987;25–33.
DelmerCSamson-DollfusDMihoutBVaschaldeYParainDFodilDBlasquezR.Topographic spectral EEG analysis in Headache.Cephalalgia1987;7:53.
19.
Ad Hoc Committee on the Classification of Headache.Classification of headache.JAMA1962;179:717–18.
20.
SAS Institute Inc.SAS guides for personal computers,version 6 edition.Cary NC:SAS Institute Inc1985.
21.
NyrkeTKangasniemiPLangAH.Difference of steady-state visual evoked potentials in classic and common migraine.Electroencephalogr Clin Neurophysiol1989;73:285–94.
22.
BlauJN.Migraine: A vasomotor instability of the meningeal circulation.Lancet1978:1136–9.
23.
LevineSRWelchKMAEwingJRRobertsonWM.Asymmetric cerebral blood flow patterns in migraine.Cephalalgia1987;7:245–8.
