Platelet serotonin uptake characm, max, y) were determined in platelet-rich plasma for 11 common migraineurs and 15 healthy volunteers. All three parameters decreased only for the three patients having a migraine collection. Migrainous platelets isolated on dextran or resuspended in control plasma exhibited normal serotonin uptake. This finding suggests that plasmatic factor(s) may be responsible for the decrease of platelet serotonin uptake observed during migraine attack.
MalmgrenROlssonPTornlingGUngeG.The 5-hydroxytryptamine take up mechanism platelets and platelets from migraine and asthmatic patients.Thromb Res1980;18:733–.
5.
Ad hoc Committee on the classification of headache.Classification of headache.J1962;179:717–18.
6.
AsterRHJandlJH.Platelet sequestration in man. I. Methods.J clin Invest1964;4.
7.
GrafMLaubscherARichardsJGPletscherA.Blood platelets isolated by polysacc reaction to 5-hydroxytryptamine.J Lab Clin Med1979;93:257–65.
8.
GaddREA.ClaymanSA reassessment of the use of modified Tyrode's solution as a medium for suspension of isolated platelets.Experientia1972;28:719–20.
9.
TuomistoJ.Anew modification for studying 5-HT uptake by blood platelets: a reeva antidepressants as uptake inhibitors.J Pharm Pharmacol1974;26:92–100.
10.
CostaJLMurphyDL.Platelet 5-HT uptake and release stopped rapidly by formald1975;255:315–8.
11.
DvilanskyARishporSNathanIZolotowZKorczynAD.Release of platelet 5-hydr plasma taken from patients during and between migraine attacks.Pain1976;2:315–18.
12.
Mück-SelerDDeanovicZDupelyM.Platelet serotonin (5-HT) an 5-HT releasing fact migrainous patientsHeadache1979;19:14–17.
13.
SandlerM.Transitory platelet monoamine oxidase deficit in migraine: some reflect1977;17:153–8.
14.
GloverVSandlerMGrantECliford RoseFOrtonDWilkinsonMStevensD.Trans in platelet monoamine oxidase activity during migraine attacks.Lancet1977;i:391–3.
15.
HaningtonEJonesRJAgmessJALWacho-wiczB.Migraine: a platelet diso1981;ii:720–3.
16.
HockadayJMWilliamsonDHWhittyCWM.Blood glucose levels and fatty acid m migraine related to fasting.Lancet1971;i:1153–6.
17.
HsuLKGCrispAHKalucyRSKovalJChenCNCarruthersMZieklaKJ. migraine-Nocturnal plasma levels of catecholamines, tryptophan, glucose and free f sleep encephalographs.Lancet1977;i:447–51.
18.
LordGDDuckworthJWCharlesworthJA.Complement activation in migraine.Lancet.
19.
HiltonBPCummingsJN.5-hydroxytryptamine levels and platelet aggregation respon with acute migraine headache.J Neurol Neurosurg Psychiatry1972;35:505–9.
20.
DaPradaMRichardsJGKettlerR.Amine storage organelles in platelets. In: Platelets in biology and pathology.Amsterdam/New York/Oxford:Elsevier/North-Hollan Press,1981:107–45.
21.
CostaJLStarkHShaferBCorashLSmithMAMurphyDL.Maximal packer size f storage vesicles of intact human platelets.Life Sci1978;23:2193–8.
22.
LaubscherAPletscherA.Uptake of 5-hydroxytryptamine in blood platelets and its in role of plasma membrane and granular storage.J Pharm Pharmacol1979;31:284–9.
