Eosinophilic ulcer of the tongue is a rarely reported clinical entity characterized histologically by a dense inflammatory infiltrate with extensive tissue eosinophilia. Clinically, this lesion can mimic squamous cell carcinoma, lymphoma, and other malignancies, as well as inflammatory or infectious processes, including Langerhans' cell histiocytosis and polymorphic reticulosis. Eosinophilic ulcers of the tongue have a benign, self-limited course; accurate histopathologic evaluation is needed to prevent unnecessary treatment.
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