Studies here and abroad are stockpiling evidence that immunoglobulin E explains only a small part of food allergy. Involvement of the entire immune system is evident if the more prevalent delayed-type food allergy is to be explained. To adequately diagnose food hypersensitivity a testing technique must be used that identifies delayed food allergy, such as the patch test here described, along with a test that diagnoses immediate immunoglobulin E-mediated food allergy.
Get full access to this article
View all access options for this article.
References
1.
BrenemanJC.Basics of food allergy. 2nd ed.Springfield, 111.: Charles C. Thomas, 1986.
2.
BrenemanJC.Handbook of food allergies. New York: Marcel Dekker, 1987.
3.
BrenemanJCSweeneyMRobertAPatch tests demonstrating immune reaction to foods. Ann Allergy1989; 62: 461–9.
4.
BrenemanJCSweeneyMRobertAImmunology of delayed type food allergy. Immunology and Allergy Practice1994;13(6):230–4.
5.
NomaTYoshizawaIMaedaKBabaMYataJ.Initial events and T cells activation in lymphokine mediated allergic responses in patients with hen egg allergy. Ann Allergy1994; 73:76–84.
6.
NomaTKawanoYYoshizawaIOvalbumin-specific induction of IL, responsiveness in lymphocytes from patients with hen egg allergy and its regulation by the culture supernatant of normal lymphocytes. Ann Allergy1990;64:33–41.
7.
KuwabaraNKondoNFukutomiOAgataHOriiT.Evaluation of patch test with dimethylsulfoxide in association with lymphocyte proliferation in food sensitive atopic dermatitis. Pediatric Asthma Allergy & Immunology1993; 7: 173–8.
8.
GellPGHCoombsRRA.Clinical aspects of immunology. 3rd ed.Philadelphia: JB Lippincott, 1975.
