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translational medicine bench-to-bedside spinal fusion rhBMP-2 peptide amphiphile

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References

Bae

Zhao

Kanim

Wong

Delamarter

Dawson

Intervariability and intravariability of bone morphogenetic proteins in commercially available demineralized bone matrix products

Spine. 200631 121299–1306

10.1097/01.brs.0000218581.92992.b7

Boden

Schimandle

Hutton

An experimental lumbar intertransverse process spinal fusion model. Radiographic, histologic, and biomechanical healing characteristics

Spine. 199520 4412–420

10.1097/00007632-199502001-00003

Carragee

Hurwitz

Weiner

A critical review of recombinant human bone morphogenetic protein-2 trials in spinal surgery: emerging safety concerns and lessons learned

Spine J 201111 6471–491

10.1016/j.spinee.2011.04.023

Chang

McClendon

Driscoll

Friday, September 28, 2018 4:05–5:05 PM abstracts: basic science of spinal fusion: 235. Peptide amphiphile nanoscaffolds potentiates the delivery of rh-BMP2 in a rabbit spine fusion model

Spine J. 201818 8S116–S117

10.1016/j.spinee.2018.06.500

Deyo

Ching

Matsen

Use of bone morphogenetic proteins in spinal fusion surgery for older adults with lumbar stenosis: trends, complications, repeat surgery, and charges

Spine. 201237 3222–230

10.1097/BRS.0b013e31821bfa3a

Duda

Grainger

Frisk

Changing the mindset in life sciences toward translation: a consensus

Sci Transl Med 2014 6 264 264cm212

10.1126/scitranslmed.aaa0599

Edelman

LaMarco

William Heberden and reverse translation

Sci Transl Med 2015 7 287 287fs220

10.1126/scitranslmed.aaa2250

El Bialy

Jiskoot

Reza

Formulation, delivery and stability of bone morphogenetic proteins for effective bone regeneration

Pharm Res 201734 61152–1170

10.1007/s11095-017-2147-x

Selph

McDonagh

Effectiveness and harms of recombinant human bone morphogenetic protein-2 in spine fusion: a systematic review and meta-analysis

Ann Intern Med 2013158 12890–902

10.7326/0003-4819-158-12-201306180-00006

10.

Geiger

Friess

Collagen sponges for bone regeneration with rhBMP-2

Adv Drug Deliv Rev 200355 121613–1629

10.1016/j.addr.2003.08.010

11.

Hartgerink

Beniash

Stupp

Self-assembly and mineralization of peptide-amphiphile nanofibers

Science. 2001294 55471684–1688

10.1126/science.1063187

12.

Hobin

Deschamps

Bockman

Engaging basic scientists in translational research: identifying opportunities, overcoming obstacles

J Transl Med 2012 10 72

10.1186/1479-5876-10-72

13.

Hsu

Nickoli

Wang

Improving the clinical evidence of bone graft substitute technology in lumbar spine surgery

Global Spine J 20122 4239–248

10.1055/s-0032-1315454

14.

Hsu

Ghodasra

Ashtekar

A comparative evaluation of factors influencing osteoinductivity among scaffolds designed for bone regeneration

Tissue Eng Part A 201319 15–161764–1772

10.1089/ten.tea.2012.0711

15.

James

LaChaud

Shen

A review of the clinical side effects of bone morphogenetic protein-2

Tissue Eng Part B Rev 201622 4284–297

10.1089/ten.teb.2015.0357

16.

Kissling

Seidenstuecker

Pilz

Suedkamp

Mayr

Bernstein

Sustained release of rhBMP-2 from microporous tricalciumphosphate using hydrogels as a carrier

BMC Biotechnol 2016 16 1 44

10.1186/s12896-016-0275-8

17.

Kurpinski

Johnson

Kumar

Desai

Mastering translational medicine: interdisciplinary education for a new generation

Sci Transl Med 2014 6 218 218fs212

10.1126/scitranslmed.3006858

18.

Lee

Hsu

Mendoza

Gel scaffolds of BMP-2-binding peptide amphiphile nanofibers for spinal arthrodesis

Adv Healthc Mater 20154 1131–141

10.1002/adhm.201400129

19.

Lee

Fyrner

Chen

Sulfated glycopeptide nanostructures for multipotent protein activation

Nat Nanotechnol 201712 8821–829

10.1038/nnano.2017.109

20.

Wozney

Delivering on the promise of bone morphogenetic proteins

Trends Biotechnol 200119 7255–265

10.1016/S0167-7799(01)01665-1

21.

Johnson

Usas

Sustained release of bone morphogenetic protein 2 via coacervate improves the osteogenic potential of muscle-derived stem cells

Stem Cells Transl Med 20132 9667–677

10.5966/sctm.2013-0027

22.

Lian

Lim

The legacy of William Heberden the Elder (1710–1801)

Rheumatology. 200443 5664–665

10.1093/rheumatology/keg007

23.

Liu

W-C

Robu

Patel

Leu

Velez

Gabriel Chu

T-M

The effects of 3D bioactive glass scaffolds and BMP-2 on bone formation in rat femoral critical size defects and adjacent bones

Biomed Mater 2014 9 4

10.1088/1748-6041/9/4/045013

24.

Lobo

Ibanez

Take a deep (nitric oxide) breath and follow the reverse translational research pathway

Eur Heart J 201839 292726–2729

10.1093/eurheartj/ehy355

25.

Mapara

Thomas

Bhat

Rabbit as an animal model for experimental research

Dent Res J (Isfahan) 20129 1111–118

10.4103/1735-3327.92960

26.

Mata

Geng

Henrikson

Bone regeneration mediated by biomimetic mineralization of a nanofiber matrix

Biomaterials. 201031 236004–6012

10.1016/j.biomaterials.2010.04.013

27.

Schroeder

Hsu

Kepler

Use of recombinant human bone morphogenetic protein-2 in the treatment of degenerative spondylolisthesis

Spine. 201641 5445–449

10.1097/BRS.0000000000001228

28.

Simmonds

Brown

JVE

Heirs

Safety and effectiveness of recombinant human bone morphogenetic protein-2 for spinal fusion: a meta-analysis of individual-participant data

Ann Intern Med 2013158 12877–889

10.7326/0003-4819-158-12-201306180-00005

29.

Urist

Bone: formation by autoinduction

Clin Orthop Relat Res 19652002 3954–10

30.

Wancket

Animal models for evaluation of bone implants and devices: comparative bone structure and common model uses

Vet Pathol 201552 5842–850

10.1177/0300985815593124

31.

Xie

Sun

Zhong

Liu

Wei

Hydroxyapatite nanoparticles as a controlled-release carrier of BMP-2: absorption and release kinetics in vitro

J Mater Sci Mater Med 201021 61875–1880

10.1007/s10856-010-4038-0

Technologies to Enhance Spinal Fusion: Bench to Bedside

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