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Research article

First published 2021-10-06

Inhibition of phase-1 biotransformation and cytostatic effects of diphenyleneiodonium on hepatoblastoma cell line HepG2 and a CYP3A4-overexpressing HepG2 cell clone

Christian Schulz, Friedrich Jung, Jan-Heiner Küpper

Clinical Hemorheology and Microcirculation

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Research article

First published 2001-3

Collagen Type I Gel Cultures of Adult Rat Hepatocytes as a Screening Induction Model for Cytochrome P450-dependent Enzymes

Karen De Smet, Christophe Cavin, Antoine Vercruysse [...]

Alternatives to Laboratory Animals

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Research article

First published 2014-10

High Performance Liquid Chromatography-Tandem Mass Spectrometry Method for Ex vivo Metabolic Studies of a Rhenium-Labeled Radiopharmaceutical for Liver Cancer

Wei-Hsi Chen, Chen-Wei Liao, Tsai-Yueh Luo [...]

European Journal of Mass Spectrometry

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Research article

First published 1993-1

Hepatic Drug Metabolism in Cystic Fibrosis: Recent Developments and Future Directions

Gregory L. Kearns

Annals of Pharmacotherapy

Free access

Research article

First published 2000-07

Effect of Melatonin on Phase I and II Biotransformation Enzymes in Streptozotocin-Induced Diabetic Rats

Alice C. Maritim, Brian H. Moore, Ruth A. Sanders [...]

International Journal of Toxicology

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Research article

First published 2009-12

Regulation of Phase II Enzymes by Genistein and Daidzein in Male and Female Swiss Webster Mice

Erik B. Froyen, Jaime L. Rudolf Reeves, Alyson E. Mitchell [...]

Journal of Medicinal Food

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Research article

First published 2002-10

Drug Metabolism Considerations in Patients With Chronic Kidney Disease

Thomas C. Dowling

Journal of Pharmacy Practice

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Research article

First published 1996-02

Effect of short-term dietary administration of eugenol in humans

Cjm Rompelberg, Jtwe Vogels, N. de Vogel [...]

Human & Experimental Toxicology

Free access

Research article

First published 2003-10

Pharmacokinetic Evaluation of 3′-Azido-2′,3′-Dideoxyuridine-5′- O -Valinate-Hydrochloride as a Prodrug of the Anti-HIV Nucleoside 3′-Azido-2′,3′-Dideoxyuridine

Linghui Kong, John S Cooperwood, Shu-Hui Christine Huang [...]

Antiviral Chemistry and Chemotherapy

Open access

Research article

First published 2019-11-13

NADPH-cytochrome P450 reductase expression and enzymatic activity in primary-like human hepatocytes and HepG2 cells for in vitro biotransformation studies

Christian Schulz, Sarah Kammerer, Jan-Heiner Küpper

Clinical Hemorheology and Microcirculation

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