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Research article

First published 2022-02

Genetic Modification of the AAV5 Capsid with Lysine Residues Results in a Lung-Tropic Liver-Detargeted Gene Transfer Vector

Katie M. Stiles, Esther Z. Frenk, Stephen M. Kaminsky [...]

Human Gene Therapy

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Brief report

First published 2011-09

Systemic Delivery of a Novel Liver-Detargeted Oncolytic Adenovirus Causes Reduced Liver Toxicity but Maintains the Antitumor Response in a Breast Cancer Bone Metastasis Model

Zhenwei Zhang, Jeffrey Krimmel, Zhiling Zhang [...]

Human Gene Therapy

Open access

Research article

First published 2013-04

Use of a Lower Dosage Liver-Detargeted AAV Vector to Prevent Hamster Muscular Dystrophy

Ida Luisa Rotundo, Alessio Lancioni, Marco Savarese [...]

Human Gene Therapy

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Research article

First published 2009-10

Replacement of Adenovirus Type 5 Fiber Shaft Heparan Sulfate Proteoglycan-Binding Domain with RGD for Improved Tumor Infectivity and Targeting

Neus Bayo-Puxan, Marta Gimenez-Alejandre, Sergio Lavilla-Alonso [...]

Human Gene Therapy

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Research article

First published 2003-11

Receptor Interactions Involved in Adenoviral-Mediated Gene Delivery After Systemic Administration in Non-Human Primates

Theodore A.G. Smith, Neeraja Idamakanti, Jennifer Marshall-Neff [...]

Human Gene Therapy

Open access

Research article

First published 2026-3

Systemic Administration of AAV9-G266A with Focused Ultrasound Enables Robust Brain Transduction with Minimal Liver Transduction

Andrew T. Nelson, Aidan Smith, Colleen T. Curley [...]

Human Gene Therapy

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Research article

First published 2009-02

Short-Term Rescue of Neonatal Lethality in a Mouse Model of Propionic Acidemia by Gene Therapy

Sean E. Hofherr, Julien S. Senac, Christopher Y. Chen [...]

Human Gene Therapy

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Research article

First published 2003-05

Adenovirus Serotype 5 Fiber Shaft Influences In Vivo Gene Transfer in Mice

Theodore A.G. Smith, Neeraja Idamakanti, Michele L. Rollence [...]

Human Gene Therapy

Retricted access

Research article

First published 2009-09

Chemical Modification with High Molecular Weight Polyethylene Glycol Reduces Transduction of Hepatocytes and Increases Efficacy of Intravenously Delivered Oncolytic Adenovirus

Konstantin Doronin, Elena V. Shashkova, Shannon M. May [...]

Human Gene Therapy

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