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Research article

First published 2022-08

Enhanced Delivery of Ligand-Conjugated Antisense Oligonucleotides (C16-HA-ASO) Targeting Dystrophia Myotonica Protein Kinase Transcripts for the Treatment of Myotonic Dystrophy Type 1

Siham Ait Benichou, Dominic Jauvin, Thiéry De Serres-Bérard [...]

Human Gene Therapy

Open access

Research article

First published 2024-01

Isolectin B4 (IB4)-conjugated streptavidin for the selective knockdown of proteins in IB4-positive (+) nociceptors

Oliver Bogen, Dionéia Araldi, Anatol Sucher [...]

Molecular Pain

Open access

Research article

First published 2023-02

Integrated Assessment of Phase 2 Data on GalNAc 3 -Conjugated 2′- O -Methoxyethyl-Modified Antisense Oligonucleotides

Brenda F. Baker, Shuting Xia, Wesley Partridge [...]

Nucleic Acid Therapeutics

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Research article

First published 2018-02

Cholesterol–GalNAc Dual Conjugation Strategy for Reducing Renal Distribution of Antisense Oligonucleotides

Fumito Wada, Tsuyoshi Yamamoto, Tetsuya Ueda [...]

Nucleic Acid Therapeutics

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Research article

First published 1994-6

Specific Targeting of Antisense Oligonucleotides to Neutrophils

Terry Y.-K. Chow, Carol Juby, Roland Brousseau

Nucleic Acid Therapeutics

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Brief report

First published 2017-08

Gene Silencing Activity and Hepatic Accumulation of Antisense Oligonucleotides Bearing Cholesterol-Conjugated Thiono Triester at the Gap Region

Mado Nakajima, Takeshi Kasuya, Shinnichi Yokota [...]

Nucleic Acid Therapeutics

Open access

Research article

First published 2024-02

Safety and Tolerability of GalNAc 3 -Conjugated Antisense Drugs Compared to the Same-Sequence 2′- O -Methoxyethyl-Modified Antisense Drugs: Results from an Integrated Assessment of Phase 1 Clinical Trial Data

Brenda F. Baker, Shuting Xia, Wesley Partridge [...]

Nucleic Acid Therapeutics

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Research article

First published 1997-06

Tissue Distribution and Metabolism of the [ 32 P]-Labeled Oligodeoxynucleoside Methylphosphonate-Neoglycopeptide Conjugate,[YEE(ah-GalNAc) 3 ]-SMCC-AET-pU m p T 7,in the Mouse

Jon J. Hangeland, John E. Flesher, Scott F. Deamond [...]

Nucleic Acid Therapeutics

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Research article

First published 1997-08

The Sequence-Specific Cleavage of RNA by Artificial Chemical Ribonucleases

Robert HÄNER, Jonathan Hall

Nucleic Acid Therapeutics

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Brief report

First published 2010-04

The Biological Effect of an Antisense Oligonucleotide Depends on Its Route of Endocytosis and Trafficking

Md. Rowshon Alam, Xin Ming, Vidula Dixit [...]

Nucleic Acid Therapeutics

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