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Research article

First published 2023-6

Over-accrual in Bayesian adaptive trials with continuous futility stopping

Leandro Garcia Barrado, Tomasz Burzykowski

Clinical Trials

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Research article

First published 2022-12

A Bayesian adaptive design for clinical trials of rare efficacy outcomes with multiple definitions

Shirin Golchi, James J Willard, Eleanor Pullenayegum [...]

Clinical Trials

Open access

Research article

First published 2018-5

Continuously updated network meta-analysis and statistical monitoring for timely decision-making

Adriani Nikolakopoulou, Dimitris Mavridis, Matthias Egger [...]

Statistical Methods in Medical Research

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Other

First published 2010-6

A flexible futility monitoring method with time-varying conditional power boundary

Ying Zhang, William R Clarke

Clinical Trials

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Other

First published 2009-12

Futility interim monitoring with control of type I and II error probabilities using the interim Z-value or confidence limit

John M Lachin

Clinical Trials

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Other

First published 2008-02

Interim futility analysis with intermediate endpoints

Bryan Goldman, Michael LeBlanc, John Crowley

Clinical Trials

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Research article

First published 2017-2

Comparison of futility monitoring guidelines using completed phase III oncology trials

Qiang Zhang, Boris Freidlin, Edward L Korn [...]

Clinical Trials

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Research article

First published 2025-9

Bayesian sequential decision-making for rare disease clinical trials

Yuan Gao, Jianling Bai, Feng Chen

Technology and Health Care

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Research article

First published 2013-4

Monitoring futility in a two-by-two factorial design: The SPS3 experience

Leslie A McClure, Christopher S Coffey, George Howard

Clinical Trials

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Research article

First published 2024-12

Comparison of Bayesian and frequentist monitoring boundaries motivated by the Multiplatform Randomized Clinical Trial

Jungnam Joo, Eric S Leifer, Michael A Proschan [...]

Clinical Trials

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