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Research article

First published 2023-12

Failure of the dual orexin receptor antagonist suvorexant to engender drug discrimination in rats

Michel A Steiner, Michael Toeroek-Schafroth, Lisa Dacome [...]

Journal of Psychopharmacology

Open access

Research article

First published 2023-12

Abuse potential assessment of the dual orexin receptor antagonist daridorexant in rats

Michel A Steiner, Michael Toeroek-Schafroth, Maria Elena Giusepponi [...]

Journal of Psychopharmacology

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Review article

First published 2022-10

Daridorexant: A New Dual Orexin Receptor Antagonist for Insomnia

Erin St. Onge, Bradley Phillips, Casey Rowe

Journal of Pharmacy Technology

Open access

Research article

First published 2021-06-01

Evaluation of SAMP8 Mice as a Model for Sleep-Wake and Rhythm Disturbances Associated with Alzheimer’s Disease: Impact of Treatment with the Dual Orexin (Hypocretin) Receptor Antagonist Lemborexant

Carsten T. Beuckmann, Hiroyuki Suzuki, Erik S. Musiek [...]

Journal of Alzheimer’s Disease

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Research article

First published 2012-8

Phase I studies on the safety,tolerability,pharmacokinetics and pharmacodynamics of SB-649868,a novel dual orexin receptor antagonist

Paolo Bettica, Gianluca Nucci, Caroline Pyke [...]

Journal of Psychopharmacology

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Review article

First published 2025-11

Rapid eye movement sleep: Who needs it? Creativity mechanisms and psychiatric applications of REM sleep enhancement

Jamie G Elliott, Jeremy A Metha, Daniel Hoyer [...]

Journal of Psychopharmacology

Free access

Review article

First published 2015-10

Suvorexant in insomnia: efficacy,safety and place in therapy

Danielle N. Rhyne, Sarah L. Anderson

Therapeutic Advances in Drug Safety

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Research article

First published 2020-3

Clinical pharmacology of the dual orexin receptor antagonist ACT-541468 in elderly subjects: Exploration of pharmacokinetics,pharmacodynamics and tolerability following single-dose morning and repeated-dose evening administration

Clemens Muehlan, Margaux Boehler, Sander Brooks [...]

Journal of Psychopharmacology

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Review article

First published 2022-2

Review of the Efficacy and Safety of Lemborexant,a Dual Receptor Orexin Antagonist (DORA),in the Treatment of Adults With Insomnia Disorder

Kristin Waters

Annals of Pharmacotherapy

Open access

Review article

First published 2018

Pharmacotherapy of Insomnia

David N Neubauer, Seithikurippu R Pandi-Perumal, David Warren Spence [...]

Journal of Central Nervous System Disease

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