Sage Journals: Discover world-class research

Retricted access

Case report

First published 2022-4

5-Fluorouracil Neurotoxicity in the Absence of Dihydropyrimidine Dehydrogenase Deficiency Case Report

Rebecca Jules, Arushi Thaper, Ryan Foster [...]

The Neurohospitalist

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Case report

First published 2026

5-Fluorouracil-induced acute leukoencephalopathy in the absence of dihydropyrimidine dehydrogenase deficiency: A case report

Murrah Sabouni, Kristen Peterson, Audrey Kam

Journal of Oncology Pharmacy Practice

Free access

Research article

First published 2003-6

Intratumoural Thymidylate Synthase and Dihydropyrimidine Dehydrogenase Activities are Good Predictors of 5-Fluorouracil Sensitivity in Colorectal Cancer

Y Ishibiki, M Kitajima, K Sakamoto [...]

Journal of International Medical Research

Free access

Research article

First published 2012-7

Tegafur–uracil is a safe alternative for the treatment of colorectal cancer in patients with partial dihydropyrimidine dehydrogenase deficiency: a proof of principle

Daniel I.G. Cubero, Felipe Melo Cruz, Patrícia Santi [...]

Therapeutic Advances in Medical Oncology

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Research article

First published 2010-6

Variants in the Dihydropyrimidine Dehydrogenase,Methylenetetrahydrofolate Reductase and Thymidylate Synthase Genes Predict Early Toxicity of 5-Fluorouracil in Colorectal Cancer Patients

MH Kristensen, PL Pedersen, GV Melsen [...]

Journal of International Medical Research

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Review article

First published 2003-01

Pharmacogenetic and clinical aspects of dihydropyrimidine dehydrogenase deficiency

Annals of Clinical Biochemistry: International Journal of Laboratory Medicine

Open access

Research article

First published 2023-1

Potential added value of combined DPYD/DPD genotyping and phenotyping to prevent severe toxicity in patients with a DPYD variant and decreased dihydropyrimidine dehydrogenase enzyme activity

Charlotte W Ockeloen, Aron Raaijmakers, Manon Hijmans-van der Vegt [...]

Journal of Oncology Pharmacy Practice

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Case report

First published 2019-1

Successful use of uridine triacetate (Vistogard) three weeks after capecitabine in a patient with homozygous dihydropyrimidine dehydrogenase mutation: A case report and review of the literature

Mira Zurayk, Yi-Kong Keung, David Yu [...]

Journal of Oncology Pharmacy Practice

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Research article

First published 2003-06

Mutational Analysis of the Human Dihydropyrimidine Dehydrogenase Gene by Denaturing High-Performance Liquid Chromatography

Joachim Fischer, Matthias Schwab, Michel Eichelbaum [...]

Genetic Testing and Molecular Biomarkers

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Research article

First published 1995-01

Human Polymorphism in Drug Metabolism: Mutation in the Dihydropyrimidine Dehydrogenase Gene Results in Exon Skipping and Thymine Uracilurea

R. Meinsma, P. Fernandez-Salguero, A.B.P. van Kuilenburg [...]

DNA and Cell Biology

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