Background:

23:T51b,

Ameloblastoma is a benign but locally aggressive neoplasm of the odontogenic epithelium, the treatment of which is controversial. A review was made of 22 patients treated for histologically diagnosed ameloblastoma between January 1975 and January 2000. We recorded data relating to patient sex, age, site of involvement, histologic type, surgical treatment, and number of recurrences. All ameloblastomas were located in the mandible. The most common histologic patterns were follicular and plexiform lesions. A total of 22.7% of the tumors were unicystic ameloblastomas. Unicystic lesions were seen to affect younger patients than the rest of the histologic types. Eighteen patients were initially treated in our center, and 4 cases were referred to our center for secondary treatment. The number of recurrences was significantly lower in patients initially treated in our center. Primary treatment comprised enucleation and bone curettage in 10 cases and radical surgery in 7. Forty percent of the unicystic lesions and 53.3% of the non-unicystic ameloblastomas of our study presented at least 1 recurrence. Ameloblastoma is a polymorphic neoplasm for which the treatment is conditioned by a number of clinical and histologic factors. An individualized preoperative study is essential for treatment.

24:T540, Background:

Ameloblastomas are a rare type of benign neoplastic tumors that are locally invasive and make up around 1% of all head-and-neck tumors. Mostly diagnosed in people between the ages of 30 and 60 years, it has a global incidence of about 0.5% of cases per million person years. Ameloblastomas are classified as multicystic, unicystic, peripheral, and desmoplastic variants. Unicystic ameloblastomas (UAs), accounting for about 6% of the cases, have a high recurrence rate. It is histologically divided into luminal, intraluminal, and mural types. As the mural variant is aggressive and has the highest chance of recurrence, radical resection of tumor is required. Case Presentation: A case of 47-year-old patient, diagnosed as unicystic mural variant of ameloblastoma presented to us in March 2023 at the department of head-and-neck surgery at a tertiary care setup in Karachi, Pakistan. Postoperatively, the patient is now on 6-month follow-up with no residual or recurrence report as of yet. Conclusion: We report a rare case of UA mural variant in the right mandible, which highlights the importance of prompt diagnosis and treatment of this type of ameloblastoma, particularly in a location where they can cause significant damage.

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Ameloblastoma Revisited

Unicystic Ameloblastoma Mural Variant: A Case Report