Sage Journals: Discover world-class research

Free access

Research article

First published 1997-12

Synthesis and Evaluation of 5-Halo 2′,3′-Didehydro-2′,3′-Dideoxynucleosides and their Blocked Phosphoramidates as Potential Anti-Human Immunodeficiency virus Agents: An Example of ‘Kinase Bypass’

C Mcguigan, S Velázquez, E De Clercq [...]

Antiviral Chemistry and Chemotherapy

Free access

Research article

First published 1997-10

Lymphatic Targeting of Anti-Human Immunodeficiency Virus Nucleosides: Pharmacokinetics of G′-Deoxy-2′,3′-Didehydrothymidine after Intravenous and Oral Administration of Dipalmitoylphosphatidyl Prodrug to Mice

KK Manouilov, Z-S Xu, LS Manouilova [...]

Antiviral Chemistry and Chemotherapy

Retricted access

Research article

First published 2004-12

Short Communication: Benefits in the Lipid Profile after Substitution of Abacavir for Stavudine: A 48-Week Prospective Study

Teresa García-Benayas, Francisco Blanco, Antonio Alcolea [...]

AIDS Research and Human Retroviruses

Free access

Research article

First published 2000-12

Correlation between Intracellular Pharmacological Activation of Nucleoside Analogues and HIV Suppression in Vitro

PG Hoggard, SD Sales, S Kewn [...]

Antiviral Chemistry and Chemotherapy

Free access

Research article

First published 2005-8

Pointer 4'-Ethynylstavudine (4'-Ed4T) Has Potent Anti-HIV-1 Activity with Reduced Toxicity and Shows a Unique Activity Profile against Drug-Resistant Mutants

Hiromichi Tanaka, Kazuhiro Haraguchi, Hiroki Kumamoto [...]

Antiviral Chemistry and Chemotherapy

Free access

Research article

First published 2004-8

Interaction of Nucleoside Inhibitors of HIV-1 Reverse Transcriptase with the Concentrative Nucleoside Transporter-1 (Slc28A1)

Pedro Cano-Soldado, Ignacio M Larráyoz, Míriam Molina-Arcas [...]

Antiviral Therapy

Free access

Brief report

First published 1996-8

Novel Nucleoside Phosphoramidates as Inhibitors of HIV: Studies on the Stereochemical Requirements of the Phosphoramidate Amino Acid

C. McGuigan, A. Salgado, C. Yarnold [...]

Antiviral Chemistry and Chemotherapy

Free access

Research article

First published 2011-2

Synthesis and an Antiviral Activity Evaluation of Nucleoside 5′- O -( N -acyl) Phosphoramidates

Katarzyna Kulik, Ewa Radzikowska, Renata Kaczmarek [...]

Antiviral Chemistry and Chemotherapy

Free access

Research article

First published 2010-5

Pyrimidine deoxynucleoside and nucleoside reverse transcriptase inhibitor metabolism in the perfused heart and isolated mitochondria

Gerald W Morris, Darcy D LaClair, Edward E McKee

Antiviral Therapy

Free access

Research article

First published 1996-2

Phosphoramidates as Potent Prodrugs of anti-HIV Nucleotides: Studies in the Amino Region

C. McGuigan, D. Cahard, A. Salgado [...]

Antiviral Chemistry and Chemotherapy

Search results