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Research article

First published 2023-11

Targeting BACE1-mediated production of amyloid beta improves hippocampal synaptic function in an experimental model of ischemic stroke

Jacob M Basak, Macy Falk, Danae N Mitchell [...]

Journal of Cerebral Blood Flow & Metabolism

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Research article

First published 2022-04-05

BACE1 Overexpression Reduces SH-SY5Y Cell Viability Through a Mechanism Distinct from Amyloid-β Peptide Accumulation: Beta Prime-Mediated Competitive Depletion of sAβPP α

Lauren Owens, Joshua Bracewell, Alexandre Benedetto [...]

Journal of Alzheimer’s Disease

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Research article

First published 2012-2-7

The BACE1-PSEN-AβPP Regulatory Axis has an Ancient Role in Response to Low Oxygen/Oxidative Stress

Seyyed Hani Moussavi Nik, Lachlan Wilson, Morgan Newman [...]

Journal of Alzheimer’s Disease

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Research article

First published 2015-3-18

Luteolin Reduces BACE1 Expression through NF-κB and Estrogen Receptor Mediated Pathways in HEK293 and SH-SY5Y Cells

Nan Zheng, Peng Yuan, Changhao Li [...]

Journal of Alzheimer’s Disease

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Research article

First published 2016-11-1

Cyclic cis -Locked Phospho-Dipeptides Reduce Entry of AβPP into Amyloidogenic Processing Pathway

Carolyn L. Fisher, Ross J. Resnick, Soumya De [...]

Journal of Alzheimer’s Disease

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Research article

First published 2020-08-18

New BACE1 Chimeric Peptide Inhibitors Selectively Prevent AβPP-β Cleavage Decreasing Amyloid-β Production and Accumulation in Alzheimer’s Disease Models

Rosa Resende, Marisa Ferreira-Marques, Patrícia Moreira [...]

Journal of Alzheimer’s Disease

Open access

Research article

First published 2022-01-11

Robust Pharmacodynamic Effect of LY3202626,a Central Nervous System Penetrant,Low Dose BACE1 Inhibitor,in Humans and Nonclinical Species

Brian A. Willis, Stephen L. Lowe, Scott A. Monk [...]

Journal of Alzheimer's Disease Reports

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Research article

First published 2022-01-18

α-Lipoic Acid Has the Potential to Normalize Copper Metabolism,Which Is Dysregulated in Alzheimer’s Disease

Kristel Metsla, Sigrid Kirss, Katrina Laks [...]

Journal of Alzheimer’s Disease

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Research article

First published 2021-09-14

Novel Plasma miRNAs as Biomarkers and Therapeutic Targets of Alzheimer’s Disease at the Prodromal Stage

Haining He, An Liu, Wei Zhang [...]

Journal of Alzheimer’s Disease

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