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Research article

First published 2022-05

Neurotoxic 18-kDa apolipoprotein E fragment production contributes to anesthetic sevoflurane-induced tau phosphorylation and neuroinflammation in vitro

Yang Yu, M Yang, X Zhuang [...]

Human & Experimental Toxicology

Free access

Research article

First published 2009-1

APOE Genotype Affects Outcome in a Murine Model of Sepsis: Implications for a New Treatment Strategy

H. Wang, D. J. Christensen, M. P. Vitek [...]

Anaesthesia and Intensive Care

Retricted access

Research article

First published 2012-10-9

Combination of Apolipoprotein E4 and High Carbohydrate Diet Reduces Hippocampal BDNF and Arc Levels and Impairs Memory in Young Mice

Silvia Maioli, Elena Puerta, Paula Merino-Serrais [...]

Journal of Alzheimer’s Disease

Open access

Research article

First published 2017-11-16

Differential Effect of APOE Alleles on Brain Glucose Metabolism in Targeted Replacement Mice: An [ 18 F]FDG-μPET Study

Marcello Venzi, Miklós Tóth, Jenny Häggkvist [...]

Journal of Alzheimer's Disease Reports

Free access

Research article

First published 2015-1

Human Apolipoprotein E ε4 Expression Impairs Cerebral Vascularization and Blood—Brain Barrier Function in Mice

Wael Alata, Yue Ye, Isabelle St-Amour [...]

Journal of Cerebral Blood Flow & Metabolism

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Research article

First published 2016-10-4

ABCA1 Agonist Reverses the ApoE4-Driven Cognitive and Brain Pathologies

Anat Boehm-Cagan, Roni Bar, Ori Liraz [...]

Journal of Alzheimer’s Disease

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Research article

First published 2016-8-3

Human ApoE ɛ 2 Promotes Regulatory Mechanisms of Bioenergetic and Synaptic Function in Female Brain: A Focus on V-type H + -ATPase

Sarah K. Woody, Helen Zhou, Shaher Ibrahimi [...]

Journal of Alzheimer’s Disease

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Research article

First published 2021-09-28

Gene-Specific DNA Methylation Linked to Postoperative Cognitive Dysfunction in Apolipoprotein E3 and E4 Mice

Katie J. Schenning, Sarah Holden, Brett A. Davis [...]

Journal of Alzheimer’s Disease

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Research article

First published 2024-11

Suppression of CNS APOE4 Expression by miRNAs Delivered by the S2 AAVrh.10 Capsid-Modified AAV Vector

Kalpita R. Karan, Slawomir Andrzejewski, Katie M. Stiles [...]

Human Gene Therapy

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Research article

First published 2026-5

Prime Editing of Alzheimer’s Disease High-Risk APOE4 Allele by Brain-Directed Adeno-Associated Virus Vectors

Caner Günaydin, Neil R. Hackett, Victor Wakim [...]

Human Gene Therapy

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