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Retricted access

Research article

First published 2016-3

CBER’s Experience With Adaptive Design Clinical Trials

Min Lin, Shiowjen Lee, Boguang Zhen [...]

Therapeutic Innovation & Regulatory Science

Open access

Research article

First published 2026

A Pragmatic Bayesian Adaptive Trial Design Based on the Value of Information: The Value-Driven Adaptive Design

Michael Dymock, Julie A. Marsh, Mark Jones [...]

Medical Decision Making

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Research article

First published 2025-9

Efficient randomized adaptive designs for multi-arm clinical trials †

Norah Alkhnefr, Feifang Hu, Guannan Zhai

Statistical Methods in Medical Research

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Review article

First published 2019

Adaptive Design: A Review of the Technical,Statistical,and Regulatory Aspects of Implementation in a Clinical Trial

Franck Pires Cerqueira, Angelo Miguel Cardoso Jesus, Maria Dulce Cotrim

Therapeutic Innovation & Regulatory Science

Open access

Research article

First published 2017-12

Development of a Bayesian response-adaptive trial design for the Dexamethasone for Excessive Menstruation study

Christian Holm Hansen, Pamela Warner, Richard A Parker [...]

Statistical Methods in Medical Research

Open access

Research article

First published 2023-10

BASIC: A Bayesian adaptive synthetic-control design for phase II clinical trials

Liyun Jiang, Peter F Thall, Fangrong Yan [...]

Clinical Trials

Open access

Research article

First published 2021-3

Bayesian adaptive decision-theoretic designs for multi-arm multi-stage clinical trials

Andrea Bassi, Johannes Berkhof, Daphne de Jong [...]

Statistical Methods in Medical Research

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Research article

First published 2026-1

Adaptive sample size re-estimation designs for a two-stage randomized trial with binary outcome

Zhixin Tang, Guogen Shan

Statistical Methods in Medical Research

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Review article

First published 2019-11

Introducing the Leapfrog Design: A Simple Bayesian Adaptive Rolling Trial Design for Accelerated Treatment Development and Optimization

Simon E. Blackwell, Marcella L. Woud, Jürgen Margraf [...]

Clinical Psychological Science

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Research article

First published 2020-6

Adaptive designs in multi-reader multi-case clinical trials of imaging devices

Zhipeng Huang, Frank Samuelson, Lucas Tcheuko [...]

Statistical Methods in Medical Research

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