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Review article

First published 2008-8

Combining Proof-of-Concept With Dose-Finding: Utilization of Adaptive Designs in Migraine Clinical Trials

A Sagkriotis, J Scholpp

Cephalalgia

Free access

Meeting report

First published 2012-11

An Adaptive,Dose-Finding,Seamless Phase 2/3 Study of a Long-Acting Glucagon-like Peptide-1 Analog (Dulaglutide): Trial Design and Baseline Characteristics

Mary Jane Geiger, Zachary Skrivanek, Brenda Gaydos [...]

Journal of Diabetes Science and Technology

Retricted access

Research article

First published 2014-3

A Continual Reassessment Method With Cohort Size Adaptation Based on Bayesian Posterior Probabilities in Phase I Dose-Finding Studies

Tomoyuki Kakizume, Satoshi Morita

Therapeutic Innovation & Regulatory Science

Retricted access

Research article

First published 2015-9

Evaluation of an Adaptive Maximizing Design Study Based on Clinical Utility Versus Morphine for TRV130 Proof-of-Concept and Dose-Regimen Finding in Patients With Postoperative Pain After Bunionectomy

James A. Bolognese, Ruth Ann Subach, Franck Skobieranda

Therapeutic Innovation & Regulatory Science

Retricted access

Research article

First published 2021-2

A Bayesian response-adaptive dose-finding and comparative effectiveness trial

Anna Heath, Maryna Yaskina, Petros Pechlivanoglou [...]

Clinical Trials

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Research article

First published 2020-4

Adaptive dose-finding based on safety and feasibility in early-phase clinical trials of adoptive cell immunotherapy

Nolan A Wages, Camilo E Fadul

Clinical Trials

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Research article

First published 2021-6

Adapting isotonic dose-finding to a dynamic set of drug combinations with application to a phase I leukemia trial

Nolan A Wages, Daniel R Reed, Michael K Keng [...]

Clinical Trials

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Research article

First published 2018-2

Phase I/II dose-finding design for molecularly targeted agent: Plateau determination using adaptive randomization

Marie-Karelle Riviere, Ying Yuan, Jacques-Henri Jourdan [...]

Statistical Methods in Medical Research

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Other

First published 2008-12

Adaptive designs for dose-finding in non-cancer phase II trials: influence of early unexpected outcomes

Matthieu Resche-Rigon, Sarah Zohar, Sylvie Chevret

Clinical Trials

Free access

Meeting report

First published 2012-11

Operational Challenges and Solutions with Implementation of an Adaptive Seamless Phase 2/3 Study

Kimberly Spencer, Kelly Colvin, Brad Braunecker [...]

Journal of Diabetes Science and Technology

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