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Research article

First published 2016-2

Tankyrase Inhibition Causes Reversible Intestinal Toxicity in Mice with a Therapeutic Index < 1

Yu Zhong, Paula Katavolos, Trung Nguyen [...]

Toxicologic Pathology

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Research article

First published 2006-2

Expanding the Therapeutic Index of Radiation Therapy by Combining In Situ Gene Therapy in the Treatment of Prostate Cancer

Michael T. Tetzlaff, Bin S. Teh, Terry L. Timme [...]

Technology in Cancer Research & Treatment

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Research article

First published 2015-7

Therapeutic futility in cancer patients at the time of palliative care transition: An analysis with a modified version of the Medication Appropriateness Index

Duarte Domingues, Rui Carneiro, Isabel Costa [...]

Palliative Medicine

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Research article

First published 2023-12

Assessment of drug-related problems associated with narrow therapeutic index drugs: A prospective cohort study

Charmi Manoj Chhatrala, Bhanu Kumar M, Ramesh Madhan [...]

Journal of Patient Safety and Risk Management

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Research article

First published 2022-02

Evaluation of Phosphorus and Non-Phosphorus Neutral Oligonucleotide Backbones for Enhancing Therapeutic Index of Gapmer Antisense Oligonucleotides

Guillermo Vasquez, Michael T. Migawa, W. Brad Wan [...]

Nucleic Acid Therapeutics

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Research article

First published 2012-12

Deficiencies of the FDA in Evaluating Generic Formulations: Addressing Narrow Therapeutic Index Drugs

Michelle Hottinger, Bryan A. Liang

American Journal of Law & Medicine

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Research article

First published 1926-1

Emetic dose of digitalis in pigeons as an index of the therapeutic dose in man.

P. J. Hanzlik, H. A. Shoemaker

Experimental Biology and Medicine

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Research article

First published 2009-05

Bioengineered Factor IX Molecules with Increased Catalytic Activity Improve the Therapeutic Index of Gene Therapy Vectors for Hemophilia B

Nicola Brunetti-Pierri, Nathan C. Grove, Yu Zuo [...]

Human Gene Therapy

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Research article

First published 2014-7

Ligand exchange on gold nanoparticles for drug delivery and enhanced therapeutic index evaluated in acute myeloid leukemia models

Shunji Egusa, Quteba Ebrahem, Reda Z Mahfouz [...]

Experimental Biology and Medicine

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Research article

First published 1995-7

Current Issues of Individual Bioequivalence

Sharon Anderson

Therapeutic Innovation & Regulatory Science

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