Sage Journals: Discover world-class research

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Research article

First published 2011-03

Preclinical Efficacy Testing in Middle-Aged Rats: Nicotinamide,a Novel Neuroprotectant,Demonstrates Diminished Preclinical Efficacy after Controlled Cortical Impact

Alicia A. Swan, Rupa Chandrashekar, Jason Beare [...]

Journal of Neurotrauma

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Research article

First published 2017-12

When Enough Is Enough: Decision Criteria for Moving a Known Drug into Clinical Testing for a New Indication in the Absence of Preclinical Efficacy Data

Jill M. Pulley, Rebecca N. Jerome, Nicole M. Zaleski [...]

ASSAY and Drug Development Technologies

Free access

Research article

First published 2016-4

Tailored Pig Models for Preclinical Efficacy and Safety Testing of Targeted Therapies

Nikolai Klymiuk, Frank Seeliger, Mohammad Bohlooly-Y [...]

Toxicologic Pathology

Free access

Research article

First published 2004-1

Trials,Tribulations,and Trends in Tumor Modeling in Mice

Joann C.L. Schuh

Toxicologic Pathology

Open access

Research article

First published 2023-02

Consensus Guidelines for the Design and In Vitro Preclinical Efficacy Testing N-of-1 Exon Skipping Antisense Oligonucleotides

Annemieke Aartsma-Rus, Alejandro Garanto, Willeke van Roon-Mom [...]

Nucleic Acid Therapeutics

Free access

Research article

First published 2016-4

Miniature Swine for Preclinical Modeling of Complexities of Human Disease for Translational Scientific Discovery and Accelerated Development of Therapies and Medical Devices

Dominic T. Schomberg, Armando Tellez, Jennifer J. Meudt [...]

Toxicologic Pathology

Free access

Review article

First published 2014-12

The potential of panobinostat as a treatment option in patients with relapsed and refractory multiple myeloma

Claudia V. Andreu-Vieyra, James R. Berenson

Therapeutic Advances in Hematology

Open access

Research article

First published 2013-08

Regimen-Specific Effects of RNA-Modified Chimeric Antigen Receptor T Cells in Mice with Advanced Leukemia

David M. Barrett, Xiaojun Liu, Shuguang Jiang [...]

Human Gene Therapy

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Research article

First published 2010-02

New Challenges for Intervertebral Disc Treatment Using Regenerative Medicine

Koichi Masuda, Jeffrey C. Lotz

Tissue Engineering Part B: Reviews

Open access

Research article

First published 2018-8

Improved functional outcome after chronic stroke with delayed anti-Nogo-A therapy: A clinically relevant intention-to-treat analysis

Katherine M Podraza, Yasmin Mehta, Vicki A Husak [...]

Journal of Cerebral Blood Flow & Metabolism

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