Sage Journals: Discover world-class research

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Research article

First published 2011-03

Preclinical Efficacy Testing in Middle-Aged Rats: Nicotinamide,a Novel Neuroprotectant,Demonstrates Diminished Preclinical Efficacy after Controlled Cortical Impact

Alicia A. Swan, Rupa Chandrashekar, Jason Beare [...]

Journal of Neurotrauma

Open access

Review article

First published 2023

Correlation of preclinical and clinical biomarkers with efficacy and toxicity of cancer immunotherapy

Lin-Peng Zheng, Jing Yang, Xie-Wan Chen [...]

Therapeutic Advances in Medical Oncology

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Research article

First published 2000-7

Preclinical Evidence for Therapeutic Efficacy of Selective Estrogen receptor Modulators for Uterine Leiomyoma

Cheryl Lyn Walker, Kevin D. Burroughs, Barbara Davis [...]

Reproductive Sciences

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Brief report

First published 2013-11

An Independent Study of the Preclinical Efficacy of C2-8 in the R6/2 Transgenic Mouse Model of Huntington's Disease

Nan Wang, Xiao-Hong Lu, Susana V. Sandoval [...]

Journal of Huntington's Disease

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Other

First published 1994-1

What Use is Toxicokinetics?

A. D. Dayan

Therapeutic Innovation & Regulatory Science

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Review article

First published 2019-04

Meta-Analysis of the Safety and Efficacy of Stem Cell Therapies for Ischemic Stroke in Preclinical and Clinical Studies

Qian Ouyang, Feng Li, Yu Xie [...]

Stem Cells and Development

Open access

Review article

First published 2025

Efficacy of Saffron ( Crocus sativus L.) and Its Constituents on Breast Cancer,a Systematic Review of Preclinical Studies and Potential Therapeutic Mechanisms

Fatemeh Sadat Hasheminasab, Maryam Azimi

Integrative Cancer Therapies

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Research article

First published 1997-1

Specialized ANTI-HIV Testing: Expediting Preclinical Drug Development

Robert W. Buckheit

Therapeutic Innovation & Regulatory Science

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Research article

First published 2017-12

When Enough Is Enough: Decision Criteria for Moving a Known Drug into Clinical Testing for a New Indication in the Absence of Preclinical Efficacy Data

Jill M. Pulley, Rebecca N. Jerome, Nicole M. Zaleski [...]

ASSAY and Drug Development Technologies

Free access

Review article

First published 2020-12

A Review of the Preclinical and Clinical Efficacy of Remdesivir,Hydroxychloroquine,and Lopinavir-Ritonavir Treatments against COVID-19

Dawid Maciorowski, Samir Z. El Idrissi, Yash Gupta [...]

Journal of Biomolecular Screening

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