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Research article

First published 1999-11

Determination of the Starting dose for Acute Oral Toxicity (LD50) Testing in the up and down Procedure (UDP) from Cytotoxicity Data

Horst Spielmann, Elke Genschow, Manfred Liebsch [...]

Alternatives to Laboratory Animals

Free access

Research article

First published 2012-5

Low dose chemotherapeutic drugs without overt cytotoxic effects decrease the secretion of VEGF by cultured human tumor cells: A tentative relationship between drug type and tumor cell type response

Sedef Hande Aktas, Hakan Akbulut, Nalan Akgun [...]

Cancer Biomarkers

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Research article

First published 2008-11

A Database of IC50 Values and Principal Component Analysis of Results from Six Basal Cytotoxicity Assays,for Use in the Modelling of the In Vivo and In Vitro Data of the EU ACuteTox Project a

Richard Clothier, Paul Dierickx, Thaly Lakhanisky [...]

Alternatives to Laboratory Animals

Free access

Research article

First published 2002-08

Optimizing Higher Throughput Methods to Assess Drug-Drug Interactions for CYP1A2,CYP2C9,CYP2C19,CYP2D6,rCYP2D6,and CYP3A4 In Vitro Using a Single Point IC50

Feng Gao, Diane L. Johnson, Sean Ekins [...]

Journal of Biomolecular Screening

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Note

First published 1993-4

A Multicentre Study of Acute In Vitro Cytotoxicity in Rat Hepatocytes: Tentative Correlation Between In Vitro Toxicities and In Vivo Data

Alain Fautrel, Christophe Chesné, André Guillouzo [...]

Alternatives to Laboratory Animals

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Research article

First published 2007-3

Conformational Changes in Proteins In Vitro as a Means of Predicting the Acute Toxicities of Chemicals

Anatoly S. Loukianov, Tatiana K. Syomina, Aleksander M. Korolev

Alternatives to Laboratory Animals

Open access

Research article

First published 2020

Hsa_Circ_0007841 Enhances Multiple Myeloma Chemotherapy Resistance Through Upregulating ABCG2

Yan Song, Ning Hu, Xiaowei Song [...]

Technology in Cancer Research & Treatment

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Research article

First published 1990-3

Hepatotoxicity of Opiates and Cocaine on Different Hepatic Cellular Systems

Ramiro Jover, Xavier Ponsoda, Jose Vicente Castell [...]

Alternatives to Laboratory Animals

Free access

Research article

First published 2013-1

Inhibition of In Vitro Leukotriene B 4 Biosynthesis in Human Neutrophil Granulocytes and Docking Studies of Natural Quinones

Premysl Landa, Zsofia Kutil, Veronika Temml [...]

Natural Product Communications

Free access

Research article

First published 2007-02

Optimizing Classification of Drug-Drug Interaction Potential for CYP450 Isoenzyme Inhibition Assays in Early Drug Discovery

Ben-Fillippo Krippendorff, Philip Lienau, Andreas Reichel [...]

Journal of Biomolecular Screening

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