Sage Journals: Discover world-class research

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Research article

First published 2019-10

A novel,hybrid,single- and multi-site clinical trial design for CLN3 disease,an ultra-rare lysosomal storage disorder

Heather R Adams, Sara Defendorf, Amy Vierhile [...]

Clinical Trials

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Research article

First published 2001-11

Mass Preparation of Primary Porcine Hepatocytes and the Design of a Hybrid Artificial Liver Module using Spheroid Culture for a Clinical Trial

J. Fukuda, R. Sakiyama, K. Nakazawa [...]

The International Journal of Artificial Organs

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Research article

First published 2026-3

A hybrid prior Bayesian method for combining domestic real-world data and overseas data in global drug development

Keer Chen, Zengyue Zheng, Pengfei Zhu [...]

Statistical Methods in Medical Research

Open access

Research article

First published 2025-10

Hybrid sample size calculations for cluster randomised trials using assurance

S. Faye Williamson, Svetlana V Tishkovskaya, Kevin J Wilson

Clinical Trials

Open access

Research article

First published 2022-7

Hybrid Experimental Designs for Intervention Development: What,Why,and How

Inbal Nahum-Shani, John J. Dziak, Maureen A. Walton [...]

Advances in Methods and Practices in Psychological Science

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Research article

First published 2011-8

Cancer clinical trials in the era of genomic signatures: Biomedical innovation,clinical utility,and regulatory-scientific hybrids

Nina Kohli-Laven, Pascale Bourret, Peter Keating [...]

Social Studies of Science

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Research article

First published 2010-10

Predictive biomarker validation in practice: lessons from real trials

Sumithra J Mandrekar, Daniel J Sargent

Clinical Trials

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Research article

First published 2025-6

A multilevel framework for recruitment and retention in implementation trials: An illustrative example

Nathaniel J Williams, Alexandra E Gomes, Nallely R Vega [...]

Clinical Trials

Open access

Research article

First published 2026

Bayesian design and analysis of two-arm cluster randomised trials using assurance: Extension to binary outcomes and comparison of Markov chain Monte Carlo and Integrated Nested Laplace Approximations

Abdullah Aloufi, Kevin J Wilson, Nina Wilson [...]

Clinical Trials

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Research article

First published 2021-8

COVID-19 vaccine trials: The potential for “hybrid” analyses

Thomas R Fleming, Martha Nason, Philip R Krause [...]

Clinical Trials

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