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Open access

Research article

First published 2023

Selective Non-toxics Inhibitors Targeting DHFR for Tuberculosis and Cancer Therapy: Pharmacophore Generation and Molecular Dynamics Simulation

Ghyzlane EL Haddoumi, Mariam Mansouri, Houda Bendani [...]

Bioinformatics and Biology Insights

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Research article

First published 1988-11

DHFR Coamplification of t-PA in DHFR + Bovine Endothelial Cells: In Vitro Characterization of the Purified Serine Protease

Richard W. Connors, Raymond W. Sweet, James P. Noveral [...]

DNA and Cell Biology

Retricted access

Research article

First published 2021-01

Identification of Selective Inhibitors of Ld DHFR Enzyme Using Pharmacoinformatic Methods

Vishnu Kumar Sharma, Prasad V. Bharatam

Journal of Computational Biology

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Research article

First published 2025-12

DHFR-Driven Metabolic Memory Sustains Periodontal Tissue Destruction

L. Nie, Y. Sun, H. Dong [...]

Journal of Dental Research

Open access

Research article

First published 2019-3

miRNA-24 Gene Sequence,DHFR −829C-T Genotypes,and Methotrexate Response in Mexican Patients with Rheumatoid Arthritis

Martha Rocio Hernández-Preciado, María Cristina Morán-Moguel, Ingrid Patricia Dávalos-Rodríguez [...]

Genetic Testing and Molecular Biomarkers

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Research article

First published 2013-04

DHFR 19-bp Deletion and SHMT C1420T Polymorphisms and Metabolite Concentrations of the Folate Pathway in Individuals with Down Syndrome

Cristiani Cortez Mendes, Aline Maria Zanchetta de Aquino Raimundo, Luciana Dutra Oliveira [...]

Genetic Testing and Molecular Biomarkers

Free access

Research article

First published 2005-10

Experimental Screening of Dihydrofolate Reductase Yields a “Test Set” of 50,000 Small Molecules for a Computational Data-Mining and Docking Competition

Nadine H. Elowe, Jan E. Blanchard, Jonathan D. Cechetto [...]

Journal of Biomolecular Screening

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Research article

First published 2002-10

Development and Effects of Immunoliposomes Carrying an Antisense Oligonucleotide Against DHFR RNA and Directed Toward Human Breast Cancer Cells Overexpressing HER2

Mercè Rodríguez, Sílvia Coma, Véronique Noé [...]

Nucleic Acid Therapeutics

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Research article

First published 2011-10

Association of MTHFR,MTR,MTRR,RFC1,and DHFR Gene Polymorphisms with Susceptibility to Sporadic Colon Cancer

Mladen Jokić, Krunoslav Brčić-Kostić, Jasminka Stefulj [...]

DNA and Cell Biology

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Research article

First published 2017-06

The Transgenic Zebrafish Display Fluorescence Reflecting the Expressional Dynamics of Dihydrofolate Reductase

Wen-Ni Chang, Wan-Yu Chi, Tseng-Ting Kao [...]

Zebrafish

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