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Articles (34)

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1-10 of 34 results for BACE-1

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Select article: Development and Characterization of a Novel Membrane Assay for Full-Length BACE-1 at pH 6.0

Free access

Research article

First published 2013-3

Development and Characterization of a Novel Membrane Assay for Full-Length BACE-1 at pH 6.0

Arman Saric, Lars zur Brügge, Dirk Müller-Pompalla [...]

Journal of Biomolecular Screening

Select article: BACE-1 is expressed in the blood–brain barrier endothelium and is upregulated in a murine model of Alzheimer’s disease

Free access

Research article

First published 2016-7

BACE-1 is expressed in the blood–brain barrier endothelium and is upregulated in a murine model of Alzheimer’s disease

Kavi Devraj, Slobodan Poznanovic, Christoph Spahn [...]

Journal of Cerebral Blood Flow & Metabolism

Select article: A new insight into computational molecular design: A case study on BACE-1 inhibitors

Retricted access

Research article

First published 2014-7

A new insight into computational molecular design: A case study on BACE-1 inhibitors

Nima Razzaghi-Asl, Bahram Hemmateenejad, Ahmad Ebadi [...]

Journal of Computational Methods in Sciences and Engineering

Select article: Accumulation of Insoluble Amyloid-β in Down's Syndrome is Associated with Increased BACE-1 and Neprilysin Activities

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Research article

First published 2011-1-7

Accumulation of Insoluble Amyloid-β in Down's Syndrome is Associated with Increased BACE-1 and Neprilysin Activities

James Scott Miners, Sean Morris, Seth Love [...]

Journal of Alzheimer’s Disease

Select article: Identification of Putative Molecular Imaging Probes for BACE-1 by Accounting for Protein Flexibility in Virtual Screening

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Research article

First published 2012-3-20

Identification of Putative Molecular Imaging Probes for BACE-1 by Accounting for Protein Flexibility in Virtual Screening

Haijing Lang, Xudong Huang, Yongliang Yang

Journal of Alzheimer’s Disease

Select article: BACE1 Dynamics Upon Inhibition with a BACE Inhibitor and Correlation to Downstream Alzheimer’s Disease Markers in Elderly Healthy Participants

Open access

Research article

First published 2017-2-20

BACE1 Dynamics Upon Inhibition with a BACE Inhibitor and Correlation to Downstream Alzheimer’s Disease Markers in Elderly Healthy Participants

Maarten Timmers, Soraia Barão, Bianca Van Broeck [...]

Journal of Alzheimer’s Disease

Select article: Kainic Acid Impairs the Memory Behavior of APP23 Mice by Increasing Brain Amyloid Load through a Tumor Necrosis Factor-α-Dependent Mechanism

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Research article

First published 2018-6-8

Kainic Acid Impairs the Memory Behavior of APP23 Mice by Increasing Brain Amyloid Load through a Tumor Necrosis Factor-α-Dependent Mechanism

Yang Ruan, Shi-Jie Guo, Xu Wang [...]

Journal of Alzheimer’s Disease

Select article: Leptin Reduces the Accumulation of Aβ and Phosphorylated Tau Induced by 27-Hydroxycholesterol in Rabbit Organotypic Slices

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Research article

First published 2010-1-28

Leptin Reduces the Accumulation of Aβ and Phosphorylated Tau Induced by 27-Hydroxycholesterol in Rabbit Organotypic Slices

Gurdeep Marwarha, Bhanu Dasari, Jaya R.P. Prasanthi [...]

Journal of Alzheimer’s Disease

Select article: The Amyloid-β 42 Proxy,Amyloid-β 25-35,Induces Normal Human Cerebral Astrocytes to Produce Amyloid-β 42

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Research article

First published 2011-4-11

The Amyloid-β 42 Proxy,Amyloid-β 25-35,Induces Normal Human Cerebral Astrocytes to Produce Amyloid-β 42

Ilaria Dal Prà, James F. Whitfileld, Raffaella Pacchiana [...]

Journal of Alzheimer’s Disease

Select article: Soluble BACE-1 Activity and sAβPPβ Concentrations in Alzheimer’s Disease and Age-Matched Healthy Control Cerebrospinal Fluid from the Alzheimer’s Disease Neuroimaging Initiative-1 Baseline Cohort

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Research article

First published

Soluble BACE-1 Activity and sAβPPβ Concentrations in Alzheimer’s Disease and Age-Matched Healthy Control Cerebrospinal Fluid from the Alzheimer’s Disease Neuroimaging Initiative-1 Baseline Cohort

Mary J. Savage, Daniel J. Holder, Guoxin Wu [...]

Journal of Alzheimer’s Disease

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